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NCT00611767 · ClinicalTrials.gov registry record · NA
GABA Mechanisms Underlying the Vulnerability to Alcohol Dependence
A NA study of Alcoholism, sponsored by Yale University.
- Completed
- Registry status
- NA
- Development phase
- 73
- Enrollment target
- 1
- Study location
NCT00611767: Completed NA study of Alcoholism, sponsored by Yale University.
NCT00611767 is a NA study of Alcoholism that has completed, run by Yale University. The registered enrollment target is 73 participants, below the 374-participant average among 65 other Alcoholism trials with a reported enrollment target (80% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00611767, a NA study of Alcoholism, has completed, sponsored by Yale University.
- COMPLETED
- Registry status
- NA
- Development phase
- 73 participants
- Enrollment target
- 1
- Study location
Study Summary
This Project will explore the hypothesis that individuals with a family history positive for alcohol dependence (without any current Axis I disorder, except nicotine dependence), experience an alteration in the reward "valence" (balance of positive and negative effects) of the GABAA receptor agonist barbiturate (thiopental) compared to family history negative age-matched subjects. Further, variation in genes involved in brain GABA function may influence the risk for alcoholism by altering a component of the discriminative stimulus effects of ethanol.
Primary Outcome
Visual Analog Scale of Similarity to Alcohol data using the Likert scale (0 Not at all similar to alcohol - 7 Extremely similar to alcohol) evaluating the similarity of drug effects to alcohol
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Thiopental
Study Locations (1)
Connecticut
- VA Connecticut Healthcare System - West Haven
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 73 participants |
| Start Date | 2005-11 |
| Est. Completion | 2012-04 |
| Phase | NA |
What the finished NCT00611767 record still lists
NCT00611767 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 73 participants, a relatively small participant target, below the 374-participant average among 65 other Alcoholism trials with a reported enrollment target (80% lower).
The record links to 1 condition, with Alcoholism appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT00611767 reports a single indexed study location in Connecticut.
Frequently Asked Questions
What is clinical trial NCT00611767 about?
NCT00611767 is a clinical study titled "GABA Mechanisms Underlying the Vulnerability to Alcohol Dependence". This Project will explore the hypothesis that individuals with a family history positive for alcohol dependence (without any current Axis I disorder, except nicotine dependence), experience an alteration in the reward "valence" (balance of positive and negative effects) of the GABAA receptor agonist...
What is the current status of trial NCT00611767?
This trial is currently completed. It is a NA study. The enrollment target is 73 participants. The study started on 2005-11. Estimated completion is 2012-04.
What conditions does trial NCT00611767 study?
This clinical trial studies the following conditions: Alcoholism.
What interventions are being tested in trial NCT00611767?
The interventions under investigation include: Placebo (DRUG), Thiopental (DRUG).
Who is sponsoring clinical trial NCT00611767?
This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00611767 being conducted?
This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Alcoholism
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00611767's enrollment target sits among peer trials
73 42nd of 65 higher than 24 of 65 other Alcoholism trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Alcoholism trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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