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ClinicalTrials.gov 11 recruiting now early-phase tilt

Alcoholism: early-phase trial registry

11 of 67 indexed Alcoholism trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #208 of 28,707 conditions by registered trial count.

67 US clinical trials · 11 currently recruiting · #208 of 28,707 conditions by registered trial count

Alcoholism: 67 US clinical trials tracked, 11 recruiting.

Alcoholism is the subject of 67 registered US clinical trials on ClinicalTrials.gov, 11 of them currently open to new participants. 14 are in Phase 3-4 (later-stage) and 26 in Phase 1-2 (earlier-stage). The most active sponsor is National Institute on Alcohol Abuse and Alcoholism (NIAAA), running 11 of these trials.

Enrollment posture brief

Registry condition alcoholism

OPEN 11 | RECR 16% | LATE 14 | EARLY 26 | RANK #208 | SPON 11

Nearest open-share peer: Stage IVA Lung Cancer AJCC v8 (16% recruiting · 37 trials)

Brain Metastases60.3%Ischemic Stroke44.8%Parenting40.3%Alcoholism (this)16%Acne Vulgaris2.9%
Open-enrollment share among volume-matched conditions near Alcoholism

Alcoholism lists 11 open slots (16% of 67 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Alcoholism on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Alcoholism is recruiting below its size-band peers.

    11 of 67 indexed trials (16.4%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Alcoholism research.

    National Institute on Alcohol Abuse and Alcoholism (NIAAA) accounts for 11 of 67 trials (16.4%). 34 distinct sponsors appear on at least one study for this condition label.

  3. Typical Alcoholism enrolment sits around 120 participants.

    Median target enrolment is 120 among the 66 trials that report a genuine target (sentinel values excluded). 30 of those (45.5%) plan for fewer than 100 participants.

  4. Alcoholism research is mostly interventional.

    56 interventional and 11 observational studies make up this index (83.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 110Phase 216Phase 33Phase 411

Open and recent trials

67 total, page 2 of 2

COMPLETED 62 participants

Neural Substrates of Approach-Avoidance Conflict

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

NCT02119624

COMPLETED Phase 3 61 participants

Quetiapine Fumarate (Seroquel) for the Treatment of Alcohol Dependence.

University of Pennsylvania

NCT00124059

COMPLETED Phase 4 57 participants

Naltrexone for Relapse Prevention

UConn Health

NCT00000442

COMPLETED Phase 1 46 participants

N-acetylcysteine in Alcohol Dependence

Minneapolis Veterans Affairs Medical Center

NCT00568087

COMPLETED NA 40 participants

Pharmacokinetic Study of Single Dose Dutasteride in Healthy Subjects

UConn Health

NCT00802321

COMPLETED Phase 4 40 participants

Zonisamide vs. Placebo in the Treatment of Alcohol Dependence

UConn Health

NCT00595556

COMPLETED Phase 4 40 participants

The Effects of Levetiracetam on Alcohol Dependent Subjects

Boston University

NCT00325182

COMPLETED Phase 2 39 participants

Baclofen for Treating Anxiety and Alcoholism

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

NCT01751386

COMPLETED Phase 2 38 participants

A Novel Pharmacotherapy for Alcoholism and Alcohol Liver Disease

Brown University

NCT01504295

COMPLETED NA 35 participants

EMPOWER AUD Pivotal Trial

Theranova, L.L.C.

NCT05948605

COMPLETED 35 participants

Exploring Gut-Brain and Brain-Gut Interactions in Alcohol Use Disorder Via Microbiota Investigations: A Pilot Study

National Institute on Drug Abuse (NIDA)

NCT03152760

COMPLETED Phase 1 27 participants

Collaborative Care for Alcohol Use Disorders in the Patient-centered Medical Home

Northwell Health

NCT02885311

COMPLETED Phase 1 22 participants

Rapid Determination Of The Clinical Utility Of Perampanel For The Treatment Of Alcohol Dependence

Virginia Commonwealth University

NCT02120365

COMPLETED Phase 1 14 participants

A Novel Compound for Alcoholism Treatment

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

NCT02039349

COMPLETED 7 participants

Acoustic Liver Biopsy in Normals and in Patients With Cirrhosis Using Endoscopic Ultrasound

Northwell Health

NCT01208311

COMPLETED Phase 1 1 participants

GSK1521498 Alcohol Interaction Study

GlaxoSmithKline

NCT01366573

COMPLETED Phase 2

Ondansetron Treatment for Alcoholism

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

NCT00000443

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Phase Distribution

PhaseTrial count
Phase 1 10
Phase 2 16
Phase 3 3
Phase 4 11

Named interventions

Most-linked intervention names on Alcoholism records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
16 trials
naltrexone (Revia) Drug
4 trials
Naltrexone Drug
4 trials
Placebo Other
4 trials
placebo Drug
3 trials
ondansetron (Zofran) Drug
2 trials
naltrexone Drug
2 trials
Brief Advice Behavioral
2 trials

US sites by state

Facility locations filed on Alcoholism trials. A trial with sites in several states counts in each.

Connecticut 13 trials
Pennsylvania 11 trials
Maryland 11 trials
California 10 trials
Texas 7 trials
New York 7 trials
Rhode Island 4 trials
Illinois 4 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Alcoholism page

67 registered trials, 11 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Alcoholism condition card totals 67 registered trials; most-linked intervention Placebo; top US site state Connecticut. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.