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ClinicalTrials.gov 11 recruiting now official registry

Alcoholism clinical trials

11 of 67 indexed Alcoholism trials are currently recruiting.

67 US clinical trials · 11 currently recruiting

Alcoholism is the subject of 67 registered US clinical trials on ClinicalTrials.gov, 11 of them currently open to new participants. 14 are in Phase 3-4 (later-stage) and 26 in Phase 1-2 (earlier-stage). The most active sponsor is National Institute on Alcohol Abuse and Alcoholism (NIAAA), running 11 of these trials.

The research picture

Alcoholism has 67 registered US clinical trials, 11 of them open to new participants right now, about 16% of the total.

11
recruiting participants now
16%
of trials open to enrollment
14
in Phase 3–4 (later-stage)
11
top sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Phase 110Phase 216Phase 33Phase 411

Active & Recent Trials

67 total, page 2 of 2

COMPLETED 62 participants

Neural Substrates of Approach-Avoidance Conflict

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

NCT02119624

COMPLETED Phase 3 61 participants

Quetiapine Fumarate (Seroquel) for the Treatment of Alcohol Dependence.

University of Pennsylvania

NCT00124059

COMPLETED Phase 4 57 participants

Naltrexone for Relapse Prevention

UConn Health

NCT00000442

COMPLETED Phase 1 46 participants

N-acetylcysteine in Alcohol Dependence

Minneapolis Veterans Affairs Medical Center

NCT00568087

COMPLETED NA 40 participants

Pharmacokinetic Study of Single Dose Dutasteride in Healthy Subjects

UConn Health

NCT00802321

COMPLETED Phase 4 40 participants

Zonisamide vs. Placebo in the Treatment of Alcohol Dependence

UConn Health

NCT00595556

COMPLETED Phase 4 40 participants

The Effects of Levetiracetam on Alcohol Dependent Subjects

Boston University

NCT00325182

COMPLETED Phase 2 39 participants

Baclofen for Treating Anxiety and Alcoholism

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

NCT01751386

COMPLETED Phase 2 38 participants

A Novel Pharmacotherapy for Alcoholism and Alcohol Liver Disease

Brown University

NCT01504295

COMPLETED NA 35 participants

EMPOWER AUD Pivotal Trial

Theranova, L.L.C.

NCT05948605

COMPLETED 35 participants

Exploring Gut-Brain and Brain-Gut Interactions in Alcohol Use Disorder Via Microbiota Investigations: A Pilot Study

National Institute on Drug Abuse (NIDA)

NCT03152760

COMPLETED Phase 1 27 participants

Collaborative Care for Alcohol Use Disorders in the Patient-centered Medical Home

Northwell Health

NCT02885311

COMPLETED Phase 1 22 participants

Rapid Determination Of The Clinical Utility Of Perampanel For The Treatment Of Alcohol Dependence

Virginia Commonwealth University

NCT02120365

COMPLETED Phase 1 14 participants

A Novel Compound for Alcoholism Treatment

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

NCT02039349

COMPLETED 7 participants

Acoustic Liver Biopsy in Normals and in Patients With Cirrhosis Using Endoscopic Ultrasound

Northwell Health

NCT01208311

COMPLETED Phase 1 1 participants

GSK1521498 Alcohol Interaction Study

GlaxoSmithKline

NCT01366573

COMPLETED Phase 2

Ondansetron Treatment for Alcoholism

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

NCT00000443

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Phase Distribution

PhaseTrial count
Phase 1 10
Phase 2 16
Phase 3 3
Phase 4 11

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Alcoholism Trial Landscape

67 indexed Alcoholism studies · 11 recruiting (16%).

Phase mix: 14 late (III/IV) vs 26 early (I/II).

Top sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA) (11 trials), 9 others listed. 17 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Alcoholism?

PlainTrial tracks 67 US clinical trials for Alcoholism, of which 11 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Alcoholism?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.