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NCT06415721 · ClinicalTrials.gov registry record · NA

Developing Functional Connectivity-Guided TMS for Alcohol Use Disorder

A NA study of Alcohol Use Disorder and Alcoholism, sponsored by VA Palo Alto Health Care System.

Recruiting
Registry status
NA
Development phase
40
Enrollment target
1
Study location

NCT06415721 is a NA study of Alcohol Use Disorder and Alcoholism that is actively recruiting participants, run by VA Palo Alto Health Care System. The registered enrollment target is 40 participants, below the 328-participant average among 184 other Alcohol Use Disorder trials with a reported enrollment target (88% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06415721, a NA study of Alcohol Use Disorder and Alcoholism, is actively recruiting participants, sponsored by VA Palo Alto Health Care System.

RECRUITING
Registry status
NA
Development phase
40 participants
Enrollment target
1
Study location

Study Summary

Alcohol Use Disorders are currently positioned as the third leading cause of preventable death in the United States, constituting a humanitarian crisis with substantial financial burden on society and medical facilities. While several pharmacological interventions exist, 60% of individuals who seek these treatments relapse to alcohol within 6 months. These high relapse rates are due in part to elevated brain response to alcohol cues in the environment. This study seeks to evaluate the efficacy of one session of functional Magnetic Resonance Imaging (fMRI) guided transcranial magnetic stimulation (TMS) as a strategy to reduce brain reactivity to alcohol cues.

Conditions Studied

Alcohol Use Disorder Alcoholism Alcohol Abuse Drinking Behavior Drinking Problem

Interventions

  • DEVICE Sham
  • DEVICE Active Transcranial Magnetic Simulation

Study Locations (1)

California

  • VA Palo Alto Health Care System - Palo Alto

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2025-08-25
Est. Completion 2026-01-01
Phase NA

Sponsor

VA Palo Alto Health Care System

34 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06415721

The ClinicalTrials.gov registry entry for NCT06415721 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 328-participant average among 184 other Alcohol Use Disorder trials with a reported enrollment target (88% lower). The listed sponsor is VA Palo Alto Health Care System, which has 34 total studies on file at ClinicalTrials.gov.

The record links to 5 conditions, with Alcohol Use Disorder appearing as the primary indexed condition, and to 2 interventions - of which Sham is the first listed.

NCT06415721 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT06415721 about?

NCT06415721 is a clinical study titled "Developing Functional Connectivity-Guided TMS for Alcohol Use Disorder". Alcohol Use Disorders are currently positioned as the third leading cause of preventable death in the United States, constituting a humanitarian crisis with substantial financial burden on society and medical facilities. While several pharmacological interventions exist, 60% of individuals who seek ...

What is the current status of trial NCT06415721?

This trial is currently recruiting. It is a NA study. The enrollment target is 40 participants. The study started on 2025-08-25. Estimated completion is 2026-01-01.

What conditions does trial NCT06415721 study?

This clinical trial studies the following conditions: Alcohol Use Disorder, Alcoholism, Alcohol Abuse, Drinking Behavior, Drinking Problem.

What interventions are being tested in trial NCT06415721?

The interventions under investigation include: Sham (DEVICE), Active Transcranial Magnetic Simulation (DEVICE).

Who is sponsoring clinical trial NCT06415721?

This trial is sponsored by VA Palo Alto Health Care System, which has 34 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06415721 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.