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NCT00342563 · ClinicalTrials.gov registry record · Phase 2

Treatment With Mecamylamine in Smoking and Non-smoking Alcohol Dependent Patients

A Phase 2 study of Alcoholism, sponsored by Yale University.

Completed
Registry status
Phase 2
Development phase
136
Enrollment target
1
Study location

NCT00342563 is a Phase 2 study of Alcoholism that has completed, run by Yale University. The registered enrollment target is 136 participants, below the 373-participant average among 65 other Alcoholism trials with a reported enrollment target (64% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00342563, a Phase 2 study of Alcoholism, has completed, sponsored by Yale University.

COMPLETED
Registry status
Phase 2
Development phase
136 participants
Enrollment target
1
Study location

Study Summary

The purpose of the study will be to evaluate the efficacy of mecamylamine in reducing alcohol consumption in smoking and non-smoking alcohol dependent patients. We hypothesize that mecamylamine will result in a greater reduction of alcohol consumption than placebo. We further hypothesize that mecamylamine will be effective in reducing both alcohol consumption and smoking in a subset of alcoholics who also smoke.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG mecamylamine

Study Locations (1)

Connecticut

  • VA Connecticut Healthcare System - West Haven

Trial Details

FieldValue
Enrollment Target 136 participants
Start Date 2004-05
Est. Completion 2015-07
Phase Phase 2

Sponsor

Yale University

1,492 total trials

What the Registry Record Tells You About NCT00342563

The ClinicalTrials.gov registry entry for NCT00342563 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 136 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 373-participant average among 65 other Alcoholism trials with a reported enrollment target (64% lower). The listed sponsor is Yale University, which has 1,492 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Alcoholism appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT00342563 reports 1 study location spanning 1 distinct geographic area - top geographies include Connecticut.

Frequently Asked Questions

What is clinical trial NCT00342563 about?

NCT00342563 is a clinical study titled "Treatment With Mecamylamine in Smoking and Non-smoking Alcohol Dependent Patients". The purpose of the study will be to evaluate the efficacy of mecamylamine in reducing alcohol consumption in smoking and non-smoking alcohol dependent patients. We hypothesize that mecamylamine will result in a greater reduction of alcohol consumption than placebo. We further hypothesize that mecam...

What is the current status of trial NCT00342563?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 136 participants. The study started on 2004-05. Estimated completion is 2015-07.

What conditions does trial NCT00342563 study?

This clinical trial studies the following conditions: Alcoholism.

What interventions are being tested in trial NCT00342563?

The interventions under investigation include: Placebo (DRUG), mecamylamine (DRUG).

Who is sponsoring clinical trial NCT00342563?

This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00342563 being conducted?

This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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