Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT06446284 · ClinicalTrials.gov registry record · NA
Target ADHD Executive Working Memory Replication Study
A NA study of ADHD, sponsored by Hartford Hospital.
- Recruiting
- Registry status
- NA
- Development phase
- 130
- Enrollment target
- 1
- Study location
NCT06446284: Recruiting NA study of ADHD, sponsored by Hartford Hospital.
NCT06446284 is a NA study of ADHD that is actively recruiting participants, run by Hartford Hospital. The registered enrollment target is 130 participants, below the 188-participant average among 75 other ADHD trials with a reported enrollment target (31% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06446284, a NA study of ADHD, is actively recruiting participants, sponsored by Hartford Hospital.
- RECRUITING
- Registry status
- NA
- Development phase
- 130 participants
- Enrollment target
- 1
- Study location
Study Summary
The proposed study will replicate target engagement as assessed in the first phase while also determining if it correlates with clinically meaningful improvements in ADHD dysfunction
Primary Outcome
fMRI measures of brain activation and functional connectivity - Conventional measures of 'brain activation' are estimated using GLM regression models that fit the fMRI BOLD timeseries data to a model of expected hemodynamic change as elicited by fMRI versions of the executive working memory training task trials. Functional connectivity is assessed using a form of cross-correlation analysis that quantifies how much the entire BOLD timeseries in different brain regions are similar to one another.
Conditions Studied
Interventions
- BEHAVIORAL EWM Training
- BEHAVIORAL Placebo Training
Study Locations (1)
Connecticut
- Institute of Living/Hartford Hospital - Hartford
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 130 participants |
| Start Date | 2023-12-01 |
| Est. Completion | 2026-12-01 |
| Phase | NA |
What NCT06446284 shows while recruiting
NCT06446284 is an interventional study that assigns participants to a tested intervention. The registered 130 participants enrollment target is mid-sized for trials with a published cap, below the 188-participant average among 75 other ADHD trials with a reported enrollment target (31% lower).
The record links to 1 condition, with ADHD appearing as the primary indexed condition, and to 2 interventions - of which EWM Training is the first listed.
NCT06446284 reports a single indexed study location in Connecticut.
Frequently Asked Questions
What is clinical trial NCT06446284 about?
NCT06446284 is a clinical study titled "Target ADHD Executive Working Memory Replication Study". The proposed study will replicate target engagement as assessed in the first phase while also determining if it correlates with clinically meaningful improvements in ADHD dysfunction
What is the current status of trial NCT06446284?
This trial is currently recruiting. It is a NA study. The enrollment target is 130 participants. The study started on 2023-12-01. Estimated completion is 2026-12-01.
What conditions does trial NCT06446284 study?
This clinical trial studies the following conditions: ADHD.
What interventions are being tested in trial NCT06446284?
The interventions under investigation include: EWM Training (BEHAVIORAL), Placebo Training (BEHAVIORAL).
Who is sponsoring clinical trial NCT06446284?
This trial is sponsored by Hartford Hospital, which has 75 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06446284 being conducted?
This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for ADHD
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06446284's enrollment target sits among peer trials
130 27th of 75 higher than 49 of 75 other ADHD trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other ADHD trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Comparative Efficacy of Organizational Skills Training (OST) and Mindfulness-Based Intervention (MBI)
RECRUITING · NA
-
Comparative Efficacy of Organizational Skills Training (OST) and Mindfulness-Based Intervention (MBI)
RECRUITING · NA
-
Fidgeting and Attentional and Emotional Regulation in ADHD
RECRUITING · NA
-
Moms Managing Attention-Deficit/Hyperactivity Disorder (ADHD) Study
RECRUITING · NA
-
A Pilot Study of a Remote ADHD Monitoring Program
RECRUITING · NA
-
Rural Autistic Individuals - Supporting Expression
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01492036 · 130 participants
Long-Term Follow-Up of Recipient of Gene Transfer Research
- NCT01631617 · 130 participants · Phase 2
Effects of Treatments on Atopic Dermatitis
- NCT02368041 · 130 participants
Utility of Thenar Near Infrared Spectroscopy (NIRS) in Pediatric Patients With Heart Failure
- NCT02604277 · 130 participants · NA
Suicidal Behavior in Patients Diagnosed With Bipolar Disorder
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI