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COMPLETED Phase 3

Smoking Cessation for Adults With Attention Deficit Hyperactivity Disorder (ADHD)

NCT00253747 · View on ClinicalTrials.gov ↗

Study Summary

The objective of this study is to evaluate whether Osmotic-Release Methylphenidate (OROS MPH), relative to placebo, increases the effectiveness of standard smoking treatment (i.e., nicotine patch and individual smoking cessation counseling) in obtaining prolonged abstinence for smokers with Attention Deficit Hyperactivity Disorder (ADHD).

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG Osmotic-Release Methylphenidate

Study Locations (6)

New York

  • VA New York Harbor Healthcare System — New York
  • New York State Psychiatric Institute - Smoking Cessation Program — New York

Massachusetts

  • Massachusetts General Hospital — Cambridge

Minnesota

  • Mayo Clinic Nicotine Research Program — Rochester

Ohio

  • Maryhaven, Inc. — Columbus

Oregon

  • Kaiser Permanente (Center for Health Research) — Portland

Trial Details

FieldValue
Enrollment Target 255 participants
Start Date 2005-11
Est. Completion 2008-03
Phase Phase 3

Sponsor

University of Cincinnati

179 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT00253747

The ClinicalTrials.gov registry entry for NCT00253747 describes a study currently listed as completed. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 255 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Cincinnati, which has 179 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 2 conditions, with Smoking appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT00253747 reports 6 study locations spanning 5 distinct geographic areas — top geographies include New York, Massachusetts, Minnesota. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT00253747 about?

NCT00253747 is a clinical study titled "Smoking Cessation for Adults With Attention Deficit Hyperactivity Disorder (ADHD)". The objective of this study is to evaluate whether Osmotic-Release Methylphenidate (OROS MPH), relative to placebo, increases the effectiveness of standard smoking treatment (i.e., nicotine patch and individual smoking cessation counseling) in obtaining prolonged abstinence for smokers with Attentio...

What is the current status of trial NCT00253747?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 255 participants. The study started on 2005-11. Estimated completion is 2008-03.

What conditions does trial NCT00253747 study?

This clinical trial studies the following conditions: Smoking, ADHD. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT00253747?

The interventions under investigation include: Placebo (DRUG), Osmotic-Release Methylphenidate (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT00253747?

This trial is sponsored by University of Cincinnati, which has 179 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT00253747 being conducted?

This trial has 6 study locations across Massachusetts, Minnesota, New York, Ohio, Oregon. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial