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Acute Kidney Injury clinical trials
33 of 75 indexed Acute Kidney Injury trials are currently recruiting.
75 US clinical trials · 33 currently recruiting
Acute Kidney Injury is the subject of 75 registered US clinical trials on ClinicalTrials.gov, 33 of them currently open to new participants. 6 are in Phase 3-4 (later-stage) and 22 in Phase 1-2 (earlier-stage). The most active sponsor is Brigham and Women's Hospital, running 3 of these trials.
The research picture
Acute Kidney Injury has 75 registered US clinical trials, 33 of them open to new participants right now, about 44% of the total.
- 33
- recruiting participants now
- 44%
- of trials open to enrollment
- 6
- in Phase 3–4 (later-stage)
- 3
- top sponsor: Brigham and Women's Hospital
Active & Recent Trials
75 total, page 2 of 2
Acute Kidney Injury Neutrophil Gelatinase-Associated Lipocalin Evaluation of Symptomatic Heart Failure Study
Alere San Diego
NCT01291836
The Drug Induced Renal Injury Consortium
Ravindra Mehta
NCT02159209
A Safety, Tolerability, Efficacy and QoL Study of Human recAP in the Treatment of Patients With SA-AKI
AM-Pharma
NCT02182440
NGAL As An Aid for the Diagnosis of Acute Kidney Injury in Intensive Care
BioPorto Diagnostics
NCT02121470
Acute Kidney Injury in Premature Infants
University of Alabama at Birmingham
NCT00573079
Evaluation of Catheter Placement for Renal Replacement Therapy in Patients With Acute Kidney Injury
Brigham and Women's Hospital
NCT02200120
Activated Vitamin D for the Prevention and Treatment of Acute Kidney Injury
David Leaf
NCT02962102
Assessment of Urinary Neutrophil Gelatinase-Associated Lipocalin to Predict AKI in the NICU
University of Alabama at Birmingham
NCT04354467
Ultrasound Markers of Organ Congestion in Severe Acute Kidney Injury
Centre hospitalier de l'Université de Montréal (CHUM)
NCT04095143
Specimen Stability Study
Astute Medical
NCT01846884
Prevention of Post-Cardiac Surgery Acute Kidney Injury by Proton Pump Inhibitor
The University of Texas Health Science Center, Houston
NCT06154226
Acute Normovolemic Hemodilution in Complex Cardiac Surgery
University of California, Los Angeles
NCT05049590
Molecular Effects of Vitamin B3 (Niacinamide) in Acute Kidney Injury
Beth Israel Deaconess Medical Center
NCT02701127
The Impact of Ketamine on Postoperative Cognitive Dysfunction, Delirium, and Renal Dysfunction
Mayo Clinic
NCT02554253
A Study of OCE-205 in Participants With Cirrhosis With Ascites Who Developed Hepatorenal Syndrome-Acute Kidney Injury
Ocelot Bio
NCT05309200
Intermittent Hypoxemia and Acute Kidney Injury Study (IHAKI Study)
Elie G. Abu Jawdeh, MD
NCT02837276
FAST GFR: Pilot Study to Evaluate the Safety of the FAST GFR Test in Patients.
FAST BioMedical
NCT01978314
The Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of FAST PV and mGFR Technology™
FAST BioMedical
NCT03095391
Fluid Chloride and AKI in Cardiopulmonary Bypass
University of New Mexi
NCT02668952
Nicotinamide Riboside in SARS-CoV-2 (COVID-19) Patients for Renal Protection
The University of Texas Health Science Center at San Antonio
NCT04818216
Pharmacokinetics of Antiepileptics in Patients on CRRT
University of Maryland, Baltimore
NCT03632915
Pharmacokinetics of MP-3180 and Use of Noninvasive Fluorescence Detection Device in Healthy Volunteers
MediBeacon
NCT02098187
Tolerability and Background Fluorescence of the MediBeacon Transdermal GFR Measurement System
MediBeacon
NCT03810833
Ibuprofen and Biomarkers of Acute Kidney Injury After Running in the Heat
University of New Mexi
NCT06247462
A Study of the PK Interaction of CXA-10 With Pravastatin and Vytorin® in Healthy Males
Complexa
NCT02547402
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 6 |
| Phase 2 | 16 |
| Phase 3 | 4 |
| Phase 4 | 2 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Acute Kidney Injury Trial Landscape
75 indexed Acute Kidney Injury studies · 33 recruiting (44%).
Phase mix: 6 late (III/IV) vs 22 early (I/II).
Top sponsor: Brigham and Women's Hospital (3 trials), 9 others listed. 25 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Acute Kidney Injury?
PlainTrial tracks 75 US clinical trials for Acute Kidney Injury, of which 33 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Acute Kidney Injury?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.