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Acute Kidney Injury: early-phase trial registry
33 of 75 indexed Acute Kidney Injury trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #178 of 28,707 conditions by registered trial count.
75 US clinical trials · 33 currently recruiting · #178 of 28,707 conditions by registered trial count
Acute Kidney Injury: 75 US clinical trials tracked, 33 recruiting.
Acute Kidney Injury is the subject of 75 registered US clinical trials on ClinicalTrials.gov, 33 of them currently open to new participants. 6 are in Phase 3-4 (later-stage) and 22 in Phase 1-2 (earlier-stage). The most active sponsor is Brigham and Women's Hospital, running 3 of these trials.
Enrollment posture brief
Registry condition acute-kidney-injury
OPEN 33 | RECR 44% | LATE 6 | EARLY 22 | RANK #178 | SPON 3
Volume-matched condition peers
Nearest open-share peer: Acute Lymphoblastic Leukemia (44% recruiting · 132 trials)
Acute Kidney Injury lists 33 open slots (44% of 75 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Acute Kidney Injury on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Acute Kidney Injury is recruiting above its size-band peers.
33 of 75 indexed trials (44%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Acute Kidney Injury trials is spread across many organizations.
Brigham and Women's Hospital accounts for 3 of 75 trials (4%). 58 distinct sponsors appear on at least one study for this condition label.
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Typical Acute Kidney Injury enrolment sits around 148 participants.
Median target enrolment is 148 among the 75 trials that report a genuine target (sentinel values excluded). 28 of those (37.3%) plan for fewer than 100 participants.
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Acute Kidney Injury splits between interventional and observational designs.
46 interventional and 29 observational studies make up this index (61.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
75 total, page 2 of 2
Acute Kidney Injury Neutrophil Gelatinase-Associated Lipocalin Evaluation of Symptomatic Heart Failure Study
Alere San Diego
NCT01291836
The Drug Induced Renal Injury Consortium
Ravindra Mehta
NCT02159209
A Safety, Tolerability, Efficacy and QoL Study of Human recAP in the Treatment of Patients With SA-AKI
AM-Pharma
NCT02182440
NGAL As An Aid for the Diagnosis of Acute Kidney Injury in Intensive Care
BioPorto Diagnostics
NCT02121470
Acute Kidney Injury in Premature Infants
University of Alabama at Birmingham
NCT00573079
Evaluation of Catheter Placement for Renal Replacement Therapy in Patients With Acute Kidney Injury
Brigham and Women's Hospital
NCT02200120
Activated Vitamin D for the Prevention and Treatment of Acute Kidney Injury
David Leaf
NCT02962102
Assessment of Urinary Neutrophil Gelatinase-Associated Lipocalin to Predict AKI in the NICU
University of Alabama at Birmingham
NCT04354467
Ultrasound Markers of Organ Congestion in Severe Acute Kidney Injury
Centre hospitalier de l'Université de Montréal (CHUM)
NCT04095143
Specimen Stability Study
Astute Medical
NCT01846884
Prevention of Post-Cardiac Surgery Acute Kidney Injury by Proton Pump Inhibitor
The University of Texas Health Science Center, Houston
NCT06154226
Acute Normovolemic Hemodilution in Complex Cardiac Surgery
University of California, Los Angeles
NCT05049590
Molecular Effects of Vitamin B3 (Niacinamide) in Acute Kidney Injury
Beth Israel Deaconess Medical Center
NCT02701127
The Impact of Ketamine on Postoperative Cognitive Dysfunction, Delirium, and Renal Dysfunction
Mayo Clinic
NCT02554253
A Study of OCE-205 in Participants With Cirrhosis With Ascites Who Developed Hepatorenal Syndrome-Acute Kidney Injury
Ocelot Bio
NCT05309200
Intermittent Hypoxemia and Acute Kidney Injury Study (IHAKI Study)
Elie G. Abu Jawdeh, MD
NCT02837276
FAST GFR: Pilot Study to Evaluate the Safety of the FAST GFR Test in Patients.
FAST BioMedical
NCT01978314
The Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of FAST PV and mGFR Technology™
FAST BioMedical
NCT03095391
Fluid Chloride and AKI in Cardiopulmonary Bypass
University of New Mexi
NCT02668952
Nicotinamide Riboside in SARS-CoV-2 (COVID-19) Patients for Renal Protection
The University of Texas Health Science Center at San Antonio
NCT04818216
Pharmacokinetics of Antiepileptics in Patients on CRRT
University of Maryland, Baltimore
NCT03632915
Pharmacokinetics of MP-3180 and Use of Noninvasive Fluorescence Detection Device in Healthy Volunteers
MediBeacon
NCT02098187
Tolerability and Background Fluorescence of the MediBeacon Transdermal GFR Measurement System
MediBeacon
NCT03810833
Ibuprofen and Biomarkers of Acute Kidney Injury After Running in the Heat
University of New Mexi
NCT06247462
A Study of the PK Interaction of CXA-10 With Pravastatin and Vytorin® in Healthy Males
Complexa
NCT02547402
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 6 |
| Phase 2 | 16 |
| Phase 3 | 4 |
| Phase 4 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Acute Kidney Injury records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Acute Kidney Injury trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Acute Kidney Injury page
75 registered trials, 33 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 33 Acute Kidney Injury trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Brigham and Women's Hospital sponsors the most Acute Kidney Injury trials on record, review their full trial history before evaluating a specific study. See Brigham and Women's Hospital's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Acute Kidney Injury condition card totals 75 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.