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ClinicalTrials.gov 33 recruiting now official registry

Acute Kidney Injury clinical trials

33 of 75 indexed Acute Kidney Injury trials are currently recruiting.

75 US clinical trials · 33 currently recruiting

Acute Kidney Injury is the subject of 75 registered US clinical trials on ClinicalTrials.gov, 33 of them currently open to new participants. 6 are in Phase 3-4 (later-stage) and 22 in Phase 1-2 (earlier-stage). The most active sponsor is Brigham and Women's Hospital, running 3 of these trials.

The research picture

Acute Kidney Injury has 75 registered US clinical trials, 33 of them open to new participants right now, about 44% of the total.

33
recruiting participants now
44%
of trials open to enrollment
6
in Phase 3–4 (later-stage)
3
top sponsor: Brigham and Women's Hospital
Phase 16Phase 216Phase 34Phase 42

Active & Recent Trials

75 total, page 2 of 2

COMPLETED 930 participants

Acute Kidney Injury Neutrophil Gelatinase-Associated Lipocalin Evaluation of Symptomatic Heart Failure Study

Alere San Diego

NCT01291836

COMPLETED 634 participants

The Drug Induced Renal Injury Consortium

Ravindra Mehta

NCT02159209

COMPLETED Phase 2 301 participants

A Safety, Tolerability, Efficacy and QoL Study of Human recAP in the Treatment of Patients With SA-AKI

AM-Pharma

NCT02182440

COMPLETED 252 participants

NGAL As An Aid for the Diagnosis of Acute Kidney Injury in Intensive Care

BioPorto Diagnostics

NCT02121470

COMPLETED 237 participants

Acute Kidney Injury in Premature Infants

University of Alabama at Birmingham

NCT00573079

COMPLETED 150 participants

Evaluation of Catheter Placement for Renal Replacement Therapy in Patients With Acute Kidney Injury

Brigham and Women's Hospital

NCT02200120

COMPLETED Phase 2 150 participants

Activated Vitamin D for the Prevention and Treatment of Acute Kidney Injury

David Leaf

NCT02962102

COMPLETED 148 participants

Assessment of Urinary Neutrophil Gelatinase-Associated Lipocalin to Predict AKI in the NICU

University of Alabama at Birmingham

NCT04354467

COMPLETED 125 participants

Ultrasound Markers of Organ Congestion in Severe Acute Kidney Injury

Centre hospitalier de l'Université de Montréal (CHUM)

NCT04095143

COMPLETED 124 participants

Specimen Stability Study

Astute Medical

NCT01846884

COMPLETED Phase 2 100 participants

Prevention of Post-Cardiac Surgery Acute Kidney Injury by Proton Pump Inhibitor

The University of Texas Health Science Center, Houston

NCT06154226

COMPLETED Phase 3 63 participants

Acute Normovolemic Hemodilution in Complex Cardiac Surgery

University of California, Los Angeles

NCT05049590

COMPLETED Early Phase 1 55 participants

Molecular Effects of Vitamin B3 (Niacinamide) in Acute Kidney Injury

Beth Israel Deaconess Medical Center

NCT02701127

COMPLETED Phase 2 52 participants

The Impact of Ketamine on Postoperative Cognitive Dysfunction, Delirium, and Renal Dysfunction

Mayo Clinic

NCT02554253

COMPLETED Phase 2 47 participants

A Study of OCE-205 in Participants With Cirrhosis With Ascites Who Developed Hepatorenal Syndrome-Acute Kidney Injury

Ocelot Bio

NCT05309200

COMPLETED 41 participants

Intermittent Hypoxemia and Acute Kidney Injury Study (IHAKI Study)

Elie G. Abu Jawdeh, MD

NCT02837276

COMPLETED NA 33 participants

FAST GFR: Pilot Study to Evaluate the Safety of the FAST GFR Test in Patients.

FAST BioMedical

NCT01978314

COMPLETED 32 participants

The Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of FAST PV and mGFR Technology™

FAST BioMedical

NCT03095391

COMPLETED Phase 2 30 participants

Fluid Chloride and AKI in Cardiopulmonary Bypass

University of New Mexi

NCT02668952

COMPLETED Phase 2 28 participants

Nicotinamide Riboside in SARS-CoV-2 (COVID-19) Patients for Renal Protection

The University of Texas Health Science Center at San Antonio

NCT04818216

COMPLETED 18 participants

Pharmacokinetics of Antiepileptics in Patients on CRRT

University of Maryland, Baltimore

NCT03632915

COMPLETED Phase 1 16 participants

Pharmacokinetics of MP-3180 and Use of Noninvasive Fluorescence Detection Device in Healthy Volunteers

MediBeacon

NCT02098187

COMPLETED NA 12 participants

Tolerability and Background Fluorescence of the MediBeacon Transdermal GFR Measurement System

MediBeacon

NCT03810833

COMPLETED Phase 1 12 participants

Ibuprofen and Biomarkers of Acute Kidney Injury After Running in the Heat

University of New Mexi

NCT06247462

COMPLETED Phase 1 10 participants

A Study of the PK Interaction of CXA-10 With Pravastatin and Vytorin® in Healthy Males

Complexa

NCT02547402

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Phase Distribution

PhaseTrial count
Phase 1 6
Phase 2 16
Phase 3 4
Phase 4 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Acute Kidney Injury Trial Landscape

75 indexed Acute Kidney Injury studies · 33 recruiting (44%).

Phase mix: 6 late (III/IV) vs 22 early (I/II).

Top sponsor: Brigham and Women's Hospital (3 trials), 9 others listed. 25 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Acute Kidney Injury?

PlainTrial tracks 75 US clinical trials for Acute Kidney Injury, of which 33 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Acute Kidney Injury?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.