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NCT03632915 · ClinicalTrials.gov registry record
Pharmacokinetics of Antiepileptics in Patients on CRRT
A clinical trial of Acute Kidney Injury and Pharmacokinetics, sponsored by University of Maryland, Baltimore.
- Completed
- Registry status
- 18
- Enrollment target
- 1
- Study location
NCT03632915: Completed study of Acute Kidney Injury and Pharmacokinetics, sponsored by University of Maryland, Baltimore.
NCT03632915 is a study of Acute Kidney Injury and Pharmacokinetics that has completed, run by University of Maryland, Baltimore. The registered enrollment target is 18 participants, below the 2,331-participant average among 74 other Acute Kidney Injury trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03632915, a study of Acute Kidney Injury and Pharmacokinetics, has completed, sponsored by University of Maryland, Baltimore.
- COMPLETED
- Registry status
- 18 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of the study is to measure levels of any of the following AEDs (levetiracetam, phenobarbital, phenytoin, ketamine, valproic acid, lacosamide) in blood and effluent on critically ill patients receiving CRRT in order to characterize drug pharmacokinetics and optimize dosing strategies in patients on CRRT.
Primary Outcome
Simultaneous samples will be taken from pre-filter, post-filter, and effluent sampling ports before dose administration, after the completion of the infusion or 1 hours post oral dose, and 6 additional time points post-infusion or post oral administration.
Conditions Studied
Interventions
- DRUG Ketamine
- DRUG Levetiracetam
- DRUG Lacosamide
- DRUG Phenytoin
- DRUG Phenobarbital
Study Locations (1)
Maryland
- University of Maryland Medical Center - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 18 participants |
| Start Date | 2017-11-20 |
| Est. Completion | 2019-12-31 |
What the finished NCT03632915 record still lists
NCT03632915 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 18 participants, a relatively small participant target, below the 2,331-participant average among 74 other Acute Kidney Injury trials with a reported enrollment target (99% lower).
The record links to 4 conditions, with Acute Kidney Injury appearing as the primary indexed condition, and to 5 interventions - of which Ketamine is the first listed.
NCT03632915 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT03632915 about?
NCT03632915 is a clinical study titled "Pharmacokinetics of Antiepileptics in Patients on CRRT". The purpose of the study is to measure levels of any of the following AEDs (levetiracetam, phenobarbital, phenytoin, ketamine, valproic acid, lacosamide) in blood and effluent on critically ill patients receiving CRRT in order to characterize drug pharmacokinetics and optimize dosing strategies in p...
What is the current status of trial NCT03632915?
This trial is currently completed. The enrollment target is 18 participants. The study started on 2017-11-20. Estimated completion is 2019-12-31.
What conditions does trial NCT03632915 study?
This clinical trial studies the following conditions: Acute Kidney Injury, Pharmacokinetics, Renal Insufficiency, Renal Failure.
What interventions are being tested in trial NCT03632915?
The interventions under investigation include: Ketamine (DRUG), Levetiracetam (DRUG), Lacosamide (DRUG), Phenytoin (DRUG), Phenobarbital (DRUG).
Who is sponsoring clinical trial NCT03632915?
This trial is sponsored by University of Maryland, Baltimore, which has 560 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03632915 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT03632915's enrollment target sits among peer trials
18 70th of 74 higher than 5 of 74 other Acute Kidney Injury trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Acute Kidney Injury trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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