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NCT06247462 · ClinicalTrials.gov registry record · Phase 1
Ibuprofen and Biomarkers of Acute Kidney Injury After Running in the Heat
A Phase 1 study of Acute Kidney Injury, sponsored by University of New Mexi.
- Completed
- Registry status
- Phase 1
- Development phase
- 12
- Enrollment target
- 1
- Study location
NCT06247462: Completed Phase 1 study of Acute Kidney Injury, sponsored by University of New Mexi.
NCT06247462 is a Phase 1 study of Acute Kidney Injury that has completed, run by University of New Mexi. The registered enrollment target is 12 participants, below the 2,331-participant average among 74 other Acute Kidney Injury trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06247462, a Phase 1 study of Acute Kidney Injury, has completed, sponsored by University of New Mexi.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 12 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this study is to determine if ibuprofen prior to exercise in the heat worsens biomarkers of acute kidney injury. Participants were given 600mg of ibuprofen or placebo (corn starch) 12- and 1-hour prior to running for 1-hour in a hot environment (35°C) at moderate intensity. Urine, plasma, and serum samples were collected pre-, post-, and 1hour post-exercise to assess biomarkers of acute kidney injury. This was a double blind, randomized crossover design, so that participants completed the alternate trial (ibuprofen or placebo) at least seven days later.
Primary Outcome
The product of urinary IGFBP7 and urinary TIMP2 (IGFBP7xTIMP2) will be measured at all time points.
Conditions Studied
Interventions
- DRUG Ibuprofen 600 mg
- DRUG Placebo Corn Starch
Study Locations (1)
New Mexico
- Exercise Physiology Lab - Albuquerque
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2023-06-01 |
| Est. Completion | 2023-09-05 |
| Phase | Phase 1 |
What the finished NCT06247462 record still lists
NCT06247462 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 2,331-participant average among 74 other Acute Kidney Injury trials with a reported enrollment target (99% lower).
The record links to 1 condition, with Acute Kidney Injury appearing as the primary indexed condition, and to 2 interventions - of which Ibuprofen 600 mg is the first listed.
NCT06247462 reports a single indexed study location in New Mexico.
Frequently Asked Questions
What is clinical trial NCT06247462 about?
NCT06247462 is a clinical study titled "Ibuprofen and Biomarkers of Acute Kidney Injury After Running in the Heat". The goal of this study is to determine if ibuprofen prior to exercise in the heat worsens biomarkers of acute kidney injury. Participants were given 600mg of ibuprofen or placebo (corn starch) 12- and 1-hour prior to running for 1-hour in a hot environment (35°C) at moderate intensity. Urine, plasma...
What is the current status of trial NCT06247462?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 12 participants. The study started on 2023-06-01. Estimated completion is 2023-09-05.
What conditions does trial NCT06247462 study?
This clinical trial studies the following conditions: Acute Kidney Injury.
What interventions are being tested in trial NCT06247462?
The interventions under investigation include: Ibuprofen 600 mg (DRUG), Placebo Corn Starch (DRUG).
Who is sponsoring clinical trial NCT06247462?
This trial is sponsored by University of New Mexi, which has 76 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06247462 being conducted?
This trial has 1 study location across New Mexico. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06247462's enrollment target sits among peer trials
12 72nd of 74 higher than 2 of 74 other Acute Kidney Injury trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Acute Kidney Injury trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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