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NCT02668952 · ClinicalTrials.gov registry record · Phase 2
Fluid Chloride and AKI in Cardiopulmonary Bypass
A Phase 2 study of Acute Kidney Injury, sponsored by University of New Mexi.
- Completed
- Registry status
- Phase 2
- Development phase
- 30
- Enrollment target
- 1
- Study location
NCT02668952: Completed Phase 2 study of Acute Kidney Injury, sponsored by University of New Mexi.
NCT02668952 is a Phase 2 study of Acute Kidney Injury that has completed, run by University of New Mexi. The registered enrollment target is 30 participants, below the 2,331-participant average among 74 other Acute Kidney Injury trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02668952, a Phase 2 study of Acute Kidney Injury, has completed, sponsored by University of New Mexi.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
Acute kidney injury (AKI) is a potential complication of cardiac surgery. In animal models, excess exogenous Cl- ion in the bloodstream is associated with AKI. Normal saline IV fluid has higher levels of Cl- ion than the blood usually carries. An alternative IV fluid sold under the name Isolyte has lower Cl- ion levels. There is no literature comparing AKI outcomes in cardiac patients between patients receiving normal saline vs. Isolyte. The investigators propose to recruit and randomize 30 trial-completing cardiac surgery patients (up to 40 enrolled) into 2 study arms and compare renal outcomes.
Primary Outcome
The difference in the \[TIMP2\]\*\[IGFBP7\] biomarker between the preoperative value and a repeated measurement at 24 hours postoperatively. Positive values represent increase; negative values represent decrease
Conditions Studied
Interventions
- DRUG 0.9% Normal Saline (0.9% Sodium Chloride) injection
- DRUG Isolyte S injection
Study Locations (1)
New Mexico
- University of New Mexico Hospital - Albuquerque
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2016-01 |
| Est. Completion | 2018-02 |
| Phase | Phase 2 |
What the finished NCT02668952 record still lists
NCT02668952 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 2,331-participant average among 74 other Acute Kidney Injury trials with a reported enrollment target (99% lower).
The record links to 1 condition, with Acute Kidney Injury appearing as the primary indexed condition, and to 2 interventions - of which 0.9% Normal Saline (0.9% Sodium Chloride) injection is the first listed.
NCT02668952 reports a single indexed study location in New Mexico.
Frequently Asked Questions
What is clinical trial NCT02668952 about?
NCT02668952 is a clinical study titled "Fluid Chloride and AKI in Cardiopulmonary Bypass". Acute kidney injury (AKI) is a potential complication of cardiac surgery. In animal models, excess exogenous Cl- ion in the bloodstream is associated with AKI. Normal saline IV fluid has higher levels of Cl- ion than the blood usually carries. An alternative IV fluid sold under the name Isolyte has ...
What is the current status of trial NCT02668952?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 30 participants. The study started on 2016-01. Estimated completion is 2018-02.
What conditions does trial NCT02668952 study?
This clinical trial studies the following conditions: Acute Kidney Injury.
What interventions are being tested in trial NCT02668952?
The interventions under investigation include: 0.9% Normal Saline (0.9% Sodium Chloride) injection (DRUG), Isolyte S injection (DRUG).
Who is sponsoring clinical trial NCT02668952?
This trial is sponsored by University of New Mexi, which has 76 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02668952 being conducted?
This trial has 1 study location across New Mexico. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Acute Kidney Injury
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02668952's enrollment target sits among peer trials
30 65th of 74 higher than 9 of 74 other Acute Kidney Injury trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Acute Kidney Injury trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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