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NCT01291836 · ClinicalTrials.gov registry record
Acute Kidney Injury Neutrophil Gelatinase-Associated Lipocalin Evaluation of Symptomatic Heart Failure Study
A clinical trial of Acute Kidney Injury and Acute Decompensated Heart Failure, sponsored by Alere San Diego.
- Completed
- Registry status
- 930
- Enrollment target
- 13
- Study locations
NCT01291836: Completed study of Acute Kidney Injury and Acute Decompensated Heart Failure, sponsored by Alere San Diego.
NCT01291836 is a study of Acute Kidney Injury and Acute Decompensated Heart Failure that has completed, run by Alere San Diego. The registered enrollment target is 930 participants, below the 2,318-participant average among 74 other Acute Kidney Injury trials with a reported enrollment target (60% lower). The trial reports 13 study locations across 8 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01291836, a study of Acute Kidney Injury and Acute Decompensated Heart Failure, has completed, sponsored by Alere San Diego.
- COMPLETED
- Registry status
- 930 participants
- Enrollment target
- 13
- Study locations
Study Summary
AKINESIS is a clinical study to assess the utility of blood and urine NGAL tests in predicting worsening kidney function in patients who present with acute heart failure (AHF) and who are treated with diuretics. It is believed that rising NGAL levels in the blood and/or urine can predict acute kidney injury. It is also believed that patients who are admitted to the hospital with high NGAL levels in the blood/urine will have poorer outcomes.
Primary Outcome
Efficacy determined by the evaluation of the area under the Receiver Operator Curve (ROC) generated from the study primary endpoint data. The units on both axes of the ROC curve are dimensionless proportions from 0 to 1.
Conditions Studied
Study Locations (13)
Other
- Athens University Hospital Attikon - Athens
- University Hospital Dublin - Dublin
- Clinica Mediterranea - Naples
- Monasterio Foundation for Medical Research and Public Health - Pisa
- Hospital Clínico Universitario Valencia - Valencia
California
- University of California San Diego Medical Center - San Diego
- San Diego Veterans Administration Hospital - San Diego
Kansas
- Kansas University Medical Center - Kansas City
Michigan
- Henry Ford Health System - Detroit
New York
- New York Methodist Hospital - Brooklyn
Virginia
- Virginia Commonweath University Medical Center - Richmond
GZ Groningen
- University of Groningen Medical Center - Groningen
Petersgraben
- Universitätsspital Basel - Basel
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 930 participants |
| Start Date | 2010-12 |
| Est. Completion | 2015-06 |
What the finished NCT01291836 record still lists
NCT01291836 is an observational study that tracks outcomes without assigning an intervention. The registered 930 participants enrollment target is mid-sized for trials with a published cap, below the 2,318-participant average among 74 other Acute Kidney Injury trials with a reported enrollment target (60% lower).
The record links to 2 conditions, with Acute Kidney Injury appearing as the primary indexed condition, and to 0 interventions.
NCT01291836 lists 13 locations in 8 states (Other, California, Kansas).
Frequently Asked Questions
What is clinical trial NCT01291836 about?
NCT01291836 is a clinical study titled "Acute Kidney Injury Neutrophil Gelatinase-Associated Lipocalin Evaluation of Symptomatic Heart Failure Study". AKINESIS is a clinical study to assess the utility of blood and urine NGAL tests in predicting worsening kidney function in patients who present with acute heart failure (AHF) and who are treated with diuretics. It is believed that rising NGAL levels in the blood and/or urine can predict acute kidne...
What is the current status of trial NCT01291836?
This trial is currently completed. The enrollment target is 930 participants. The study started on 2010-12. Estimated completion is 2015-06.
What conditions does trial NCT01291836 study?
This clinical trial studies the following conditions: Acute Kidney Injury, Acute Decompensated Heart Failure.
Who is sponsoring clinical trial NCT01291836?
This trial is sponsored by Alere San Diego, which has 2 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01291836 being conducted?
This trial has 13 study locations across California, Kansas, Michigan, New York, Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT01291836's enrollment target sits among peer trials
930 13th of 74 higher than 62 of 74 other Acute Kidney Injury trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Acute Kidney Injury trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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