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NCT02098187 · ClinicalTrials.gov registry record · Phase 1
Pharmacokinetics of MP-3180 and Use of Noninvasive Fluorescence Detection Device in Healthy Volunteers
A Phase 1 study of Acute Kidney Injury and Glomerular Filtration Rate, sponsored by MediBeacon.
- Completed
- Registry status
- Phase 1
- Development phase
- 16
- Enrollment target
- 1
- Study location
NCT02098187: Completed Phase 1 study of Acute Kidney Injury and Glomerular Filtration Rate, sponsored by MediBeacon.
NCT02098187 is a Phase 1 study of Acute Kidney Injury and Glomerular Filtration Rate that has completed, run by MediBeacon. The registered enrollment target is 16 participants, below the 2,331-participant average among 74 other Acute Kidney Injury trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02098187, a Phase 1 study of Acute Kidney Injury and Glomerular Filtration Rate, has completed, sponsored by MediBeacon.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 16 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this early feasibility study was to investigate the pharmacokinetics of MP-3180 administered in rising doses and to evaluate the use of the Optical Renal Function Monitor (ORFM), an investigational noninvasive fluorescence detection device.
Primary Outcome
Blood samples were collected and analyzed using validated analytical methods. Total plasma clearance (the volume of plasma cleared of the drug over time) was calculated as: Clp = Dose/ AUC∞.
Conditions Studied
Interventions
- DRUG Below target dose MP-3180
- DRUG At target dose MP-3180
- DRUG 2 times above target dose MP-3180
- DRUG 4 times above target dose MP-3180
- DEVICE ORFM prototype
Study Locations (1)
Maryland
- University of Maryland - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2014-03 |
| Est. Completion | 2014-03 |
| Phase | Phase 1 |
What the finished NCT02098187 record still lists
NCT02098187 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 16 participants, a relatively small participant target, below the 2,331-participant average among 74 other Acute Kidney Injury trials with a reported enrollment target (99% lower).
The record links to 2 conditions, with Acute Kidney Injury appearing as the primary indexed condition, and to 5 interventions - of which Below target dose MP-3180 is the first listed.
NCT02098187 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT02098187 about?
NCT02098187 is a clinical study titled "Pharmacokinetics of MP-3180 and Use of Noninvasive Fluorescence Detection Device in Healthy Volunteers". The purpose of this early feasibility study was to investigate the pharmacokinetics of MP-3180 administered in rising doses and to evaluate the use of the Optical Renal Function Monitor (ORFM), an investigational noninvasive fluorescence detection device.
What is the current status of trial NCT02098187?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 16 participants. The study started on 2014-03. Estimated completion is 2014-03.
What conditions does trial NCT02098187 study?
This clinical trial studies the following conditions: Acute Kidney Injury, Glomerular Filtration Rate.
What interventions are being tested in trial NCT02098187?
The interventions under investigation include: Below target dose MP-3180 (DRUG), At target dose MP-3180 (DRUG), 2 times above target dose MP-3180 (DRUG), 4 times above target dose MP-3180 (DRUG), ORFM prototype (DEVICE).
Who is sponsoring clinical trial NCT02098187?
This trial is sponsored by MediBeacon, which has 11 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02098187 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Acute Kidney Injury
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02098187's enrollment target sits among peer trials
16 71st of 74 higher than 4 of 74 other Acute Kidney Injury trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Acute Kidney Injury trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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