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NCT04095143 · ClinicalTrials.gov registry record

Ultrasound Markers of Organ Congestion in Severe Acute Kidney Injury

A clinical trial of Acute Kidney Injury and Fluid Overload, sponsored by Centre hospitalier de l'Université de Montréal (CHUM).

Completed
Registry status
125
Enrollment target
6
Study locations

NCT04095143 is a study of Acute Kidney Injury and Fluid Overload that has completed, run by Centre hospitalier de l'Université de Montréal (CHUM). The registered enrollment target is 125 participants, below the 2,329-participant average among 74 other Acute Kidney Injury trials with a reported enrollment target (95% lower). The trial reports 6 study locations across 4 states.

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The verdict

NCT04095143, a study of Acute Kidney Injury and Fluid Overload, has completed, sponsored by Centre hospitalier de l'Université de Montréal (CHUM).

COMPLETED
Registry status
125 participants
Enrollment target
6
Study locations

Study Summary

Fluid overload is associated with adverse outcomes in patients with severe acute kidney injury. It remains unclear if fluid overload is merely a marker of disease severity or if organ congestion is a mediator of complications. Point-of-care ultrasound could be a modality used to assess organ congestion and its clinical implications. The objective of this study is to determine whether ultrasound markers of organ congestion are associated with major adverse kidney events in critically ill patients with severe acute kidney injury.

Interventions

  • DIAGNOSTIC_TEST Portal vein flow
  • DIAGNOSTIC_TEST Intra-renal flow
  • DIAGNOSTIC_TEST Hepatic vein flow
  • DIAGNOSTIC_TEST Pulmonary B-lines
  • DIAGNOSTIC_TEST Dimensions of the inferior vena cava

Study Locations (6)

Ontario

  • Sunnybrook Health Science Centre - Toronto
  • St. Michael's hospital - Toronto

Quebec

  • Centre Hospitalier de l'Université de Montréal - Montreal
  • Montreal Heart Institute - Montreal

Kentucky

  • University of Kentucky - Lexington

Alberta

  • University of Alberta - Edmonton

Trial Details

FieldValue
Enrollment Target 125 participants
Start Date 2018-09-04
Est. Completion 2022-09-01

What the Registry Record Tells You About NCT04095143

The ClinicalTrials.gov registry entry for NCT04095143 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 125 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,329-participant average among 74 other Acute Kidney Injury trials with a reported enrollment target (95% lower). The listed sponsor is Centre hospitalier de l'Université de Montréal (CHUM), which has 10 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Acute Kidney Injury appearing as the primary indexed condition, and to 5 interventions - of which Portal vein flow is the first listed.

NCT04095143 reports 6 study locations spanning 4 distinct geographic areas - top geographies include Ontario, Quebec, Kentucky.

Frequently Asked Questions

What is clinical trial NCT04095143 about?

NCT04095143 is a clinical study titled "Ultrasound Markers of Organ Congestion in Severe Acute Kidney Injury". Fluid overload is associated with adverse outcomes in patients with severe acute kidney injury. It remains unclear if fluid overload is merely a marker of disease severity or if organ congestion is a mediator of complications. Point-of-care ultrasound could be a modality used to assess organ congest...

What is the current status of trial NCT04095143?

This trial is currently completed. The enrollment target is 125 participants. The study started on 2018-09-04. Estimated completion is 2022-09-01.

What conditions does trial NCT04095143 study?

This clinical trial studies the following conditions: Acute Kidney Injury, Fluid Overload, Ultrasonography.

What interventions are being tested in trial NCT04095143?

The interventions under investigation include: Portal vein flow (DIAGNOSTIC_TEST), Intra-renal flow (DIAGNOSTIC_TEST), Hepatic vein flow (DIAGNOSTIC_TEST), Pulmonary B-lines (DIAGNOSTIC_TEST), Dimensions of the inferior vena cava (DIAGNOSTIC_TEST).

Who is sponsoring clinical trial NCT04095143?

This trial is sponsored by Centre hospitalier de l'Université de Montréal (CHUM), which has 10 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04095143 being conducted?

This trial has 6 study locations across Kentucky, Alberta, Ontario, Quebec. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.