University of Pennsylvania

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, University of Pennsylvania sits in the top decile of US sponsors by registered trial count (#15 of 15,751 sponsors by registered trial count).

1,423 total trials 199 currently recruiting 982 completed early-phase tilt top decile by trial count

University of Pennsylvania: 1,423 sponsored US clinical trials, 199 recruiting.

University of Pennsylvania sponsors 1,423 registered US clinical trials on ClinicalTrials.gov, 199 of them currently recruiting, and 982 completed. 130 of these trials are in Phase 3-4 (later-stage) and 339 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 17 trials.

Top-decile sponsor footprint

University of Pennsylvania ranks in the top decile of sponsors by registered trial count (#15 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

1,423 total, page 13 of 29

COMPLETED Phase 4

Partial Reinforcement II: Three Approaches to Maintenance Therapy for Chronic Insomnia

NCT03774810

COMPLETED

Opioid Taper Study

NCT03912298

COMPLETED NA

Behavioral Economic Approaches to Increase Physical Activity Among Patients With Elevated Risk for Cardiovascular Disease

NCT03911141

COMPLETED

Task Augmentation of Transcranial Magnetic Stimulation (TMS)

NCT04586205

COMPLETED Phase 1

Remote Observed Dosing of Suboxone to Improve Clinical Practice

NCT03769025

TERMINATED NA

Network Control TMS fMRI

NCT05736458

COMPLETED NA

Behavioral Science and Hepatitis C Screening Outreach

NCT03712553

COMPLETED NA

The Music, Sleep and Dementia Study

NCT04157244

TERMINATED Phase 1

DC Vaccine in Colorectal Cancer

NCT03730948

COMPLETED Phase 1

CART-EGFRvIII + Pembrolizumab in GBM

NCT03726515

COMPLETED

Diabetes Reversal and the Subgingival Microbiota

NCT05501093

COMPLETED NA

Study of Therapeutic Exercise in Acute Respiratory Failure to Improve Neuromuscular Disability Trial

NCT03863470

COMPLETED NA

A Randomized Controlled Trial of Imago Relationship Therapy

NCT04302844

COMPLETED NA

Light Treatment Effectiveness (LITE) Study

NCT03726489

COMPLETED NA

Low-Level Laser in Treatment of Head and Neck Lymphedema: A Pilot Study

NCT03738332

COMPLETED NA

Disseminating a Digital ACP Platform (Our Care Wishes) to Hospitalized Patients

NCT03727685

COMPLETED NA

Evaluating Risk Factors and Biomarkers for Adaptation and Resilience to Spaceflight

NCT03786016

COMPLETED NA

Enhanced Recovery After Spine Surgery Randomized Clinical Trial

NCT05830331

COMPLETED Phase 1

A Study of INO-A002 in Healthy Dengue Virus-naive Adults

NCT03831503

COMPLETED NA

Incentivizing Buprenorphine-Naloxone Initiation in Emergency Departments

NCT03821103

TERMINATED Phase 2

Imiquimod for Preventing Keloid Recurrence

NCT03760250

COMPLETED Phase 2

Low Dose Naltrexone to Improve Physical Health in Patients With Vasculitis

NCT03482479

COMPLETED NA

BE Intervention for Naloxone Uptake

NCT06064981

COMPLETED NA

Vending Labeling Sales and Intercepts Study

NCT06260176

TERMINATED Phase 1

FMISO PET/CT Imaging Trial for Assessing Hypoxia in Soft Tissue Sarcomas

NCT03730077

COMPLETED Phase 2

Study of huCART19 for Very High-Risk (VHR) Subsets of Pediatric B-ALL

NCT03792633

COMPLETED NA

Preventing Rehospitalization in Lung Transplant Recipients Utilizing mHealth

NCT03792698

COMPLETED NA

Evaluation of the Novel Use of Gamification With Alternative Goal-setting Experiences

NCT03749473

COMPLETED

Chronic Insomnia and CSF Markers of Dementia

NCT04024020

COMPLETED NA

Effects of Insomnia Treatment on Metabolism in Patients With Depression

NCT04719143

COMPLETED Phase 1

Transplanting Hepatitis C Lungs Into Negative Lung Recipients

NCT03724149

COMPLETED NA

Mobile Health (mHealth) Nutrition Intervention for Children With Autism Spectrum Disorder

NCT03424811

TERMINATED

Validation of Point of Care Liver Function Tests

NCT03800069

COMPLETED NA

TrueTear in Sjogren's Disease Patients

NCT03719885

COMPLETED

PET Imaging in Patients With Suspected Cardiac Sarcoidosis

NCT03746847

COMPLETED NA

Psoriatic Arthritis and Psoriasis Treatment Decision Aid

NCT03737045

TERMINATED

Electrogram-Guided Myocardial Advanced Phenotyping

NCT03293381

COMPLETED NA

Automated Navigation to Improve Outpatient Colonoscopy Adherence

NCT03710213

COMPLETED Phase 1

DC Vaccine in Pancreatic Cancer

NCT03592888

COMPLETED NA

Advanced Heart Care at Home

NCT03724695

COMPLETED Phase 1

A Women-Focused PrEP Intervention

NCT03699722

COMPLETED NA

Prospective Use of Awake Endoscopy for Inspire Activation

NCT03990298

COMPLETED NA

The Use of PARO to Decrease Agitation in Persons With Dementia and/or Delirium

NCT05565703

TERMINATED Phase 1

MOv19-BBz CAR T Cells in aFR Expressing Recurrent High Grade Serous Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

NCT03585764

COMPLETED NA

Behavioral Weight Loss and Stigma Reduction

NCT03704064

COMPLETED NA

Comparison of a Web-based Advance Directive to a Standard Advance Directive

NCT03676426

COMPLETED NA

Esophageal Cooling for AF Ablation

NCT03691571

TERMINATED NA

Adductor Canal Block (ACB) vs Femoral Nerve Block (FNB) in Revision Total Knee Arthroplasty

NCT03697538

COMPLETED NA

Active Choice in the EHR to Promote Statin Therapy

NCT03271931

COMPLETED

Circulating miRNA in Primary Hyperparathyroidism

NCT03931109

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Phase Distribution

PhaseTrial count
Phase 1 182
Phase 2 157
Phase 3 43
Phase 4 87

What is open in the University of Pennsylvania pipeline

199 recruiting of 1,423 indexed (14% open); 982 completed (69%).

Phase mix: 130 late (III/IV) vs 339 early (I/II) (early-phase heavy).

Top condition: Obesity (17 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.