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NCT04586205 · ClinicalTrials.gov registry record
Task Augmentation of Transcranial Magnetic Stimulation (TMS)
A clinical trial, sponsored by University of Pennsylvania.
- Completed
- Registry status
- 17
- Enrollment target
NCT04586205: Completed study, sponsored by University of Pennsylvania.
NCT04586205 is a clinical trial that has completed, run by University of Pennsylvania. The registered enrollment target is 17 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04586205 has completed, sponsored by University of Pennsylvania.
- COMPLETED
- Registry status
- 17 participants
- Enrollment target
Study Summary
This pilot, within-subjects, randomized proof-of-concept study investigates the effects of activating the DLPFC promotion system on TMS treatment outcomes. Twenty-five healthy volunteers will participate in four sessions involving either active or sham repetitive transcranial magnetic stimulation (rTMS). Using anatomically guided TMS paired with cognitive tasks, the study tests the hypothesis that cognitive paired associative stimulation enhances cortical responses. For this pilot study, we are focusing only on the augmentation of TMS with the IASP task.
Primary Outcome
This Sternberg Sorting Task (SST) task is designed to assess how individuals store and retrieve random information from short-term memory. This task was administered to all participants before they were randomized into one of two groups (active TMS first then sham TMS or sham TMS first then active TMS). 0's were recorded for incorrect responses and 1's were recorded for correct responses. Therefore, the mean represents the accuracy percentage for each group.
Interventions
- OTHER MRI
- DEVICE active TMS
- DEVICE sham TMS
- BEHAVIORAL IASP Task
- BEHAVIORAL SST Task
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 17 participants |
| Start Date | 2019-04-07 |
| Est. Completion | 2024-03-11 |
What the finished NCT04586205 record still lists
NCT04586205 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 17 participants, a relatively small participant target.
The record links to 0 conditions, and to 5 interventions - of which MRI is the first listed.
NCT04586205 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04586205 about?
NCT04586205 is a clinical study titled "Task Augmentation of Transcranial Magnetic Stimulation (TMS)". This pilot, within-subjects, randomized proof-of-concept study investigates the effects of activating the DLPFC promotion system on TMS treatment outcomes. Twenty-five healthy volunteers will participate in four sessions involving either active or sham repetitive transcranial magnetic stimulation (r...
What is the current status of trial NCT04586205?
This trial is currently completed. The enrollment target is 17 participants. The study started on 2019-04-07. Estimated completion is 2024-03-11.
What interventions are being tested in trial NCT04586205?
The interventions under investigation include: MRI (OTHER), active TMS (DEVICE), sham TMS (DEVICE), IASP Task (BEHAVIORAL), SST Task (BEHAVIORAL).
Who is sponsoring clinical trial NCT04586205?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
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