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NCT03912298 · ClinicalTrials.gov registry record
Opioid Taper Study
A clinical trial, sponsored by University of Pennsylvania.
- Completed
- Registry status
- 7
- Enrollment target
NCT03912298: Completed study, sponsored by University of Pennsylvania.
NCT03912298 is a clinical trial that has completed, run by University of Pennsylvania. The registered enrollment target is 7 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03912298 has completed, sponsored by University of Pennsylvania.
- COMPLETED
- Registry status
- 7 participants
- Enrollment target
Study Summary
The purpose of this study is to determine the effect of opioid taper on pain sensitivity in patients with chronic pain. In a well-characterized sample of men and women with chronic neuropathic pain on high-dose opioid therapy, experimental pain responses (cold-pressor, quantitative sensory testing) will be serially described over the course of and following an individualized opioid taper. In addition, functional improvements and subject-level predictors of response will be described.
Primary Outcome
Pain perception will be measured using the cold-pressor test (CPT) employing procedures consistent with those described in the literature. Order of pain testing will vary, and three aspects of the pain response will be captured at each study session: evoked pain; temporal summation; and conditioned pain modulation, which map on to the hypothesized peripheral, spinal and supra-spinal mechanisms of OIH. Reported are cold-pressor pain tolerance prior to and following taper.
Interventions
- OTHER Opioid Taper Pain perception
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 7 participants |
| Start Date | 2019-04-15 |
| Est. Completion | 2021-05-31 |
What the finished NCT03912298 record still lists
NCT03912298 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 7 participants, a relatively small participant target.
The record links to 0 conditions, and to 1 intervention - of which Opioid Taper Pain perception is the first listed.
NCT03912298 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03912298 about?
NCT03912298 is a clinical study titled "Opioid Taper Study". The purpose of this study is to determine the effect of opioid taper on pain sensitivity in patients with chronic pain. In a well-characterized sample of men and women with chronic neuropathic pain on high-dose opioid therapy, experimental pain responses (cold-pressor, quantitative sensory testing) ...
What is the current status of trial NCT03912298?
This trial is currently completed. The enrollment target is 7 participants. The study started on 2019-04-15. Estimated completion is 2021-05-31.
What interventions are being tested in trial NCT03912298?
The interventions under investigation include: Opioid Taper Pain perception (OTHER).
Who is sponsoring clinical trial NCT03912298?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
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