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NCT04024020 · ClinicalTrials.gov registry record
Chronic Insomnia and CSF Markers of Dementia
A clinical trial, sponsored by University of Pennsylvania.
- Completed
- Registry status
- 30
- Enrollment target
NCT04024020: Completed study, sponsored by University of Pennsylvania.
NCT04024020 is a clinical trial that has completed, run by University of Pennsylvania. The registered enrollment target is 30 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04024020 has completed, sponsored by University of Pennsylvania.
- COMPLETED
- Registry status
- 30 participants
- Enrollment target
Study Summary
The longstanding view has been that insomnia, and other forms of sleep disturbance, emerge as a consequence of dementia and are the result of progressive neuronal damage. However, there is growing evidence that the direction of causation may go both ways, with sleep disturbance potentially increasing vulnerability to dementia. Longitudinal studies have found that sleep disturbance often precedes and increases risk for dementia by several years.The purpose of this study is to examine the relationship between chronic insomnia and dementia biomarkers and orexin levels found in cerebrospinal fluid (CSF). Fifteen adults age 30-50 with chronic insomnia and age- and gender-matched good sleepers will undergo overnight polysomnography and CSF sampling in the morning.
Interventions
- OTHER lumbar puncture
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2019-01-01 |
| Est. Completion | 2023-10-31 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04024020
The ClinicalTrials.gov registry entry for NCT04024020 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Pennsylvania, which has 1,423 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which lumbar puncture is the first listed.
NCT04024020 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT04024020 about?
NCT04024020 is a clinical study titled "Chronic Insomnia and CSF Markers of Dementia". The longstanding view has been that insomnia, and other forms of sleep disturbance, emerge as a consequence of dementia and are the result of progressive neuronal damage. However, there is growing evidence that the direction of causation may go both ways, with sleep disturbance potentially increasin...
What is the current status of trial NCT04024020?
This trial is currently completed. The enrollment target is 30 participants. The study started on 2019-01-01. Estimated completion is 2023-10-31.
What interventions are being tested in trial NCT04024020?
The interventions under investigation include: lumbar puncture (OTHER).
Who is sponsoring clinical trial NCT04024020?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
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