University of North Carolina, Chapel Hill

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, University of North Carolina, Chapel Hill sits in the top decile of US sponsors by registered trial count (#28 of 15,742 sponsors by registered trial count).

1,109 total trials 108 currently recruiting 881 completed early-phase tilt top decile by trial count

University of North Carolina, Chapel Hill: 1,109 sponsored US clinical trials, 108 recruiting.

University of North Carolina, Chapel Hill sponsors 1,109 registered US clinical trials on ClinicalTrials.gov, 108 of them currently recruiting, and 881 completed. 69 of these trials are in Phase 3-4 (later-stage) and 203 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 17 trials.

Top-decile sponsor footprint

University of North Carolina, Chapel Hill ranks in the top decile of sponsors by registered trial count (#28 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 69/100

881 of 962 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (91.6%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,109 total, page 2 of 23

RECRUITING Phase 2

Prevention/Reduction of ASRs and PTSD to Sustain Civilian Performance With Sublingual Cyclobenzaprine HCl (TNX-102 SL)

NCT06636786

RECRUITING NA

Stress Trajectories and Anhedonia in Adolescence Research Study

NCT07040449

RECRUITING NA

FAMily-centered WEight Loss for Black Adults (FAM WEL B-ing)

NCT06724406

RECRUITING NA

Improving Appetite Self-Regulation in African American Adults With Type 2 Diabetes

NCT05741125

RECRUITING NA

Treating Binge Eating and Obesity Digitally in Black Women

NCT05693896

RECRUITING NA

Physical Activity and Community EmPOWERment Project

NCT06740162

RECRUITING NA

Efficacy & Safety of LOBO™ Vascular Occlusion Device for Embolization of Pulmonary Arteriovenous Malformations

NCT06735976

RECRUITING NA

Resilience Through Interventions for Successful Early Outcomes

NCT06669624

RECRUITING NA

Graded Exposure and Mindfulness Meditation for Patients Post-ACL Reconstruction

NCT05949177

RECRUITING

Eating Disorders Genetics Initiative 2

NCT06594913

RECRUITING Phase 4

Hypertonic Saline in NCFB

NCT06242795

RECRUITING NA

Teachers Leading the Front Lines - North Carolina (Tealeaf-NC)

NCT06587230

RECRUITING NA

Behavioral Approaches to Reduce Diabetes Distress in Adults With Type 1 Diabetes: A Pragmatic SMART

NCT06405373

RECRUITING Phase 4

Ovarian Hormone Withdrawal, Anhedonia, and Reward Sensitivity in Women With Premenstrual Exacerbations of Depression

NCT06610305

RECRUITING NA

Promoting Improved Functioning Among People Experiencing Stressful Situations

NCT06482567

RECRUITING Phase 1

Dose Optimization of Caffeine for HIE

NCT06448780

RECRUITING NA

Flexibility, Alcohol Misuse, and Excitation

NCT06634771

RECRUITING Phase 4

Rifaximin for the Secondary Prevention of Recurrent Pouchitis

NCT06312683

RECRUITING NA

Effects of "Alliance180 Program" on Well-Being

NCT06451523

RECRUITING NA

A Pragmatic Rehabilitation Intervention: The Active Rehab Study

NCT05320822

RECRUITING Phase 4

Beta-Blocker Influences on Inflammatory and Neural Responses to Stress

NCT06263452

RECRUITING NA

Apathy in Parkinson Disease TMS Study

NCT06087926

RECRUITING NA

Ultrasound for Evaluation of Percutaneous G-tube Position

NCT06361498

RECRUITING Phase 2

The EFfect of FinErenone in Kidney TransplantiOn Recipients: The EFFEKTOR Study

NCT06059664

RECRUITING Phase 3

Psilocybin-Assisted Therapy in Treatment-Resistant Depression

NCT06303739

RECRUITING NA

Optimizing Telehealth-delivery of a Weight Loss Intervention in Older Adults

NCT06044571

RECRUITING NA

Evaluating a National Person-Centered Training Program to Strengthen the Dementia Care Workforce

NCT06239688

RECRUITING Phase 3

Supraclavicular Bupivacaine Vs. Supraclavicular Liposomal Bupivacaine for Orthopedic Wrist Surgery

NCT06179004

RECRUITING NA

3-D Tractography FUS Ablation for Essential Tremor

NCT06331052

RECRUITING NA

Adverse Adolescent Pathways to Substance Use

NCT06977178

RECRUITING NA

Avocado Consumption, Nutrients in Human Milk, and Infant Cognitive Development

NCT06208085

RECRUITING NA

Feasibility Test of Action Planning in Pediatric IBD

NCT06186752

RECRUITING NA

Comparing Cognitive-Behavioral Therapy Versus Mindfulness-Based Therapy for Autistic Adults

NCT06060860

RECRUITING NA

The Validation Study of Bioelectronics

NCT05397951

RECRUITING NA

Fit for Duty: mHealth Intervention for Weight Gain Prevention

NCT06110273

RECRUITING NA

Precision Medicine and Physical Function

NCT05877846

RECRUITING NA

GI Alpha-Gal Study

NCT06268717

RECRUITING NA

Education and Employment Support for HIV Prevention in Young Adults (ENSPIRE)

NCT06096324

RECRUITING NA

Virtual Reality Mindfulness Meditation After ACL Reconstruction

NCT05527171

RECRUITING NA

Adolescent Mood During Puberty and Testosterone

NCT06072677

RECRUITING NA

Targeted Motor Learning to Improve Gait for Individuals With Parkinson Disease

NCT05864157

RECRUITING NA

Cochlear Implants in Young Children With SSD

NCT05775367

RECRUITING NA

Gait Rehabilitation to Treat FastOA

NCT05848622

RECRUITING NA

Accountability for Care Through Undoing Racism & Equity for Moms

NCT05484804

RECRUITING NA

Animal Assisted Therapy in Pediatric Dentistry

NCT05464888

RECRUITING Phase 2

Evaluation of Endometriosis With 18F-fluorofuranylnorprogesterone PET / MRI

NCT05480995

RECRUITING NA

Depression, Aging, Stress and Heart Health Study

NCT05570721

RECRUITING NA

Sitting Interruption and Whole-body Cardiovascular Health

NCT05316571

RECRUITING NA

Child-Adult Relationship Enhancement in Primary Care (PriCARE) / Criando Niños Con CARIÑO (CARIÑO)

NCT05233150

RECRUITING Phase 4

Examining the Effects of Estradiol on Neural and Molecular Response to Reward

NCT05282277

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Phase Distribution

PhaseTrial count
Phase 1 111
Phase 2 92
Phase 3 13
Phase 4 56

What is open in the University of North Carolina, Chapel Hill pipeline

108 recruiting of 1,109 indexed (10% open); 881 completed (79%).

Phase mix: 69 late (III/IV) vs 203 early (I/II) (early-phase heavy).

Top condition: Obesity (17 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

University of North Carolina, Chapel Hill: open-pipeline peers nationwide

Peers matched on 1,109 registered trials and 10% open enrollment, not the therapeutic-area sidebar.

University of North Carolina, Chapel Hill sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,500 8%10%12%14%16%18%20% Total trials Recruiting share University of North Carolina, Chapel HillUniversity of FloridaWake Forest University Health SciencesUniversity of Alabama at BirminghamNYU Langone HealthChildren's Hospitals and Clinics of MinnesotaCytokineticsSanofiOhio University
University of North Carolina, Chapel Hill sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

University of North Carolina, Chapel Hill sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,109 trials (± recruiting share)

Sponsors near 10% open enrollment (± trial volume)

What to do with this University of North Carolina, Chapel Hill page

1,109 registered trials is a research-attention snapshot, not an endorsement of University of North Carolina, Chapel Hill or any single study.

  • 108 of University of North Carolina, Chapel Hill's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Obesity is the condition University of North Carolina, Chapel Hill studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Obesity trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

University of North Carolina, Chapel Hill pipeline card: 1,109 registered trials from official public datasets.Report a data error.