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NCT06696001 · ClinicalTrials.gov registry record · NA
Neuroscience of Psychotherapy for Depression
A NA study of Depression, sponsored by University of North Carolina, Chapel Hill.
- Recruiting
- Registry status
- NA
- Development phase
- 45
- Enrollment target
- 1
- Study location
NCT06696001: Recruiting NA study of Depression, sponsored by University of North Carolina, Chapel Hill.
NCT06696001 is a NA study of Depression that is actively recruiting participants, run by University of North Carolina, Chapel Hill. The registered enrollment target is 45 participants, below the 786-participant average among 679 other Depression trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06696001, a NA study of Depression, is actively recruiting participants, sponsored by University of North Carolina, Chapel Hill.
- RECRUITING
- Registry status
- NA
- Development phase
- 45 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this study is to learn the extent to which client-therapist brain activity may synchronize during a psychosocial intervention for depression symptoms. The study will compare behavioral activation, a client-centered type of cognitive-behavioral therapy, to psychoeducation which delivers information on strategies to recover from depression symptoms. Participants will answer questions about their mental and physical health, attend one psychosocial intervention session receiving either Behavioral Activation or Psychoeducation with simultaneous brain activity measurement and complete follow up surveys two weeks and one month following the intervention.
Primary Outcome
Inter-brain synchronization will be calculated for the Alpha frequency band via phase locking value during the interventional session for both study arms and will be used to assess any potential differences in Alpha frequency inter-brain synchronization between groups
Conditions Studied
Interventions
- BEHAVIORAL Psychoeducation
- BEHAVIORAL Behavioral Activation
Study Locations (1)
North Carolina
- Carolina Center for Neurostimulation - Chapel Hill
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 45 participants |
| Start Date | 2025-04-11 |
| Est. Completion | 2026-06-30 |
| Phase | NA |
What NCT06696001 shows while recruiting
NCT06696001 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 45 participants, a relatively small participant target, below the 786-participant average among 679 other Depression trials with a reported enrollment target (94% lower).
The record links to 1 condition, with Depression appearing as the primary indexed condition, and to 2 interventions - of which Psychoeducation is the first listed.
NCT06696001 reports a single indexed study location in North Carolina.
Frequently Asked Questions
What is clinical trial NCT06696001 about?
NCT06696001 is a clinical study titled "Neuroscience of Psychotherapy for Depression". The goal of this study is to learn the extent to which client-therapist brain activity may synchronize during a psychosocial intervention for depression symptoms. The study will compare behavioral activation, a client-centered type of cognitive-behavioral therapy, to psychoeducation which delivers ...
What is the current status of trial NCT06696001?
This trial is currently recruiting. It is a NA study. The enrollment target is 45 participants. The study started on 2025-04-11. Estimated completion is 2026-06-30.
What conditions does trial NCT06696001 study?
This clinical trial studies the following conditions: Depression.
What interventions are being tested in trial NCT06696001?
The interventions under investigation include: Psychoeducation (BEHAVIORAL), Behavioral Activation (BEHAVIORAL).
Who is sponsoring clinical trial NCT06696001?
This trial is sponsored by University of North Carolina, Chapel Hill, which has 1,109 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06696001 being conducted?
This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Depression
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06696001's enrollment target sits among peer trials
45 488th of 679 higher than 186 of 679 other Depression trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Depression trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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