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NCT06880640 · ClinicalTrials.gov registry record · NA

Affect-based Impulsivity in Borderline Personality Disorder

A NA study of Healthy Controls Group - Age and Sex-matched and Borderline Personality Disorder (BPD), sponsored by University of North Carolina, Chapel Hill.

Recruiting
Registry status
NA
Development phase
106
Enrollment target
1
Study location

NCT06880640: Recruiting NA study of Healthy Controls Group - Age and Sex-matched and Borderline Personality Disorder (BPD), sponsored by University of North Carolina, Chapel Hill.

NCT06880640 is a NA study of Healthy Controls Group - Age and Sex-matched and Borderline Personality Disorder (BPD) that is actively recruiting participants, run by University of North Carolina, Chapel Hill. The registered enrollment target is 106 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (92% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06880640, a NA study of Healthy Controls Group - Age and Sex-matched and Borderline Personality Disorder (BPD), is actively recruiting participants, sponsored by University of North Carolina, Chapel Hill.

RECRUITING
Registry status
NA
Development phase
106 participants
Enrollment target
1
Study location

Study Summary

The purpose of this research study is to investigate how personality traits and neuroendocrine systems relate to decision-making patterns in individuals 18-45 years old. The main question it aims to answer is how neuroendocrine activity impacts decision-making. Participants will complete online behavioral tasks, a stress induction procedure, self-report surveys, and a cognitive assessment. During the session, psychophysiological measures will be collected, including electrocardiogram (ECG) and cardiac impedance (ICG) to monitor heart rate and blood flow, as well as electrodermal activity (EDA), blood drop samples, and saliva collection to assess nervous system activity.

Primary Outcome

Measured by choice behavior in SDTT, which is based on the decision tree framework. After each action, participants receive feedback about the effect of that action and the extent to which it added to or took away from their points. If participants make a given choice, the subsequent actions that they can choose are different than if they were to initially make a different choice. An action in SDTT is goal-directed if the possible net gain an individual can earn before the end of the current ep

Interventions

  • BEHAVIORAL Stress Induction

Study Locations (1)

North Carolina

  • University of North Carolina at Chapel Hill - Chapel Hill

Trial Details

FieldValue
Enrollment Target 106 participants
Start Date 2025-09-21
Est. Completion 2026-08
Phase NA

What NCT06880640 shows while recruiting

NCT06880640 is an interventional study that assigns participants to a tested intervention. The registered 106 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (92% lower).

The record links to 2 conditions, with Healthy Controls Group - Age and Sex-matched appearing as the primary indexed condition, and to 1 intervention - of which Stress Induction is the first listed.

NCT06880640 reports a single indexed study location in North Carolina.

Frequently Asked Questions

What is clinical trial NCT06880640 about?

NCT06880640 is a clinical study titled "Affect-based Impulsivity in Borderline Personality Disorder". The purpose of this research study is to investigate how personality traits and neuroendocrine systems relate to decision-making patterns in individuals 18-45 years old. The main question it aims to answer is how neuroendocrine activity impacts decision-making. Participants will complete online beh...

What is the current status of trial NCT06880640?

This trial is currently recruiting. It is a NA study. The enrollment target is 106 participants. The study started on 2025-09-21. Estimated completion is 2026-08.

What conditions does trial NCT06880640 study?

This clinical trial studies the following conditions: Healthy Controls Group - Age and Sex-matched, Borderline Personality Disorder (BPD).

What interventions are being tested in trial NCT06880640?

The interventions under investigation include: Stress Induction (BEHAVIORAL).

Who is sponsoring clinical trial NCT06880640?

This trial is sponsored by University of North Carolina, Chapel Hill, which has 1,109 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06880640 being conducted?

This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Healthy Controls Group - Age and Sex-matched

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06880640's enrollment target sits among peer trials

106 830th of 2000 higher than 1,167 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06880640, the US trial registry maintained by the National Library of Medicine. NCT06880640 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.