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NCT07337902 · ClinicalTrials.gov registry record · NA
Comparing Over the Counter Pain Medicines for Discomfort in Crohn's Disease (AVID-CD)
A NA study of Crohn's Disease (CD) and Dysmenorrhea Primary, sponsored by University of North Carolina, Chapel Hill.
- Recruiting
- Registry status
- NA
- Development phase
- 24
- Enrollment target
- 1
- Study location
NCT07337902: Recruiting NA study of Crohn's Disease (CD) and Dysmenorrhea Primary, sponsored by University of North Carolina, Chapel Hill.
NCT07337902 is a NA study of Crohn's Disease (CD) and Dysmenorrhea Primary that is actively recruiting participants, run by University of North Carolina, Chapel Hill. The registered enrollment target is 24 participants, below the 184-participant average among 6 other Crohn's Disease (CD) trials with a reported enrollment target (87% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07337902, a NA study of Crohn's Disease (CD) and Dysmenorrhea Primary, is actively recruiting participants, sponsored by University of North Carolina, Chapel Hill.
- RECRUITING
- Registry status
- NA
- Development phase
- 24 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this pilot study is to prepare for a larger study that will compare the effectiveness and safety of two common pain medications, ibuprofen and acetaminophen, to help treat period cramps in women with Crohn's disease. The goal of this study is to identify any challenges in running a larger study. The investigators will track how many people sign up for the study, how well participants follow the study plan, how many people stay in the study, and whether they are able to complete all the study activities, such as taking the medication, submitting samples, and filling out surveys. During the study, participants will undergo a screening visit that includes a blood draw, physical exam, pregnancy test, stool testing, and complete surveys about Crohn's disease and menstrual cycles. Once this visit is complete, the rest of the study will occur at home. Participants will be assigned to take either ibuprofen or acetaminophen to help treat period cramps for four menstrual cycles in a row. Participants will take ibuprofen for two cycles and acetaminophen for two cycles. Participants will know which medication is being taken at any given time, but the order in which they take the medications will be randomly assigned. Before each menstrual cycle, participants will submit a stool sample and fill out a short (\<1 minute) electronic survey. When participants develop period cramps, they will take the assigned medication for three days and fill out short (\<1 minute) electronic surveys about their cramps. After participants finish taking the medication for three days, they will submit another stool sample and fill out two more short (\<1 minute) electronic surveys. After have completing this process for four menstrual cycles, a remote interview with a researcher to give feedback on the study will be conducted.
Primary Outcome
Accrual will be determined as the proportion of participants who express interest in the study out of those contacted
Conditions Studied
Interventions
- OTHER Acetaminophen
- OTHER Ibuprofen
Study Locations (1)
North Carolina
- University of North Carolina at Chapel Hill - Chapel Hill
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2026-03-18 |
| Est. Completion | 2028-07 |
| Phase | NA |
What NCT07337902 shows while recruiting
NCT07337902 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 184-participant average among 6 other Crohn's Disease (CD) trials with a reported enrollment target (87% lower).
The record links to 2 conditions, with Crohn's Disease (CD) appearing as the primary indexed condition, and to 2 interventions - of which Acetaminophen is the first listed.
NCT07337902 reports a single indexed study location in North Carolina.
Frequently Asked Questions
What is clinical trial NCT07337902 about?
NCT07337902 is a clinical study titled "Comparing Over the Counter Pain Medicines for Discomfort in Crohn's Disease (AVID-CD)". The purpose of this pilot study is to prepare for a larger study that will compare the effectiveness and safety of two common pain medications, ibuprofen and acetaminophen, to help treat period cramps in women with Crohn's disease. The goal of this study is to identify any challenges in running a la...
What is the current status of trial NCT07337902?
This trial is currently recruiting. It is a NA study. The enrollment target is 24 participants. The study started on 2026-03-18. Estimated completion is 2028-07.
What conditions does trial NCT07337902 study?
This clinical trial studies the following conditions: Crohn's Disease (CD), Dysmenorrhea Primary.
What interventions are being tested in trial NCT07337902?
The interventions under investigation include: Acetaminophen (OTHER), Ibuprofen (OTHER).
Who is sponsoring clinical trial NCT07337902?
This trial is sponsored by University of North Carolina, Chapel Hill, which has 1,109 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07337902 being conducted?
This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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