University of Missouri-Columbia

Open enrollment across a mixed-phase pipeline

According to ClinicalTrials.gov-derived indexes, University of Missouri-Columbia sits in the top decile of US sponsors by registered trial count (#120 of 15,742 sponsors by registered trial count).

291 total trials 54 currently recruiting 170 completed top decile by trial count

University of Missouri-Columbia: 291 sponsored US clinical trials, 54 recruiting.

University of Missouri-Columbia sponsors 291 registered US clinical trials on ClinicalTrials.gov, 54 of them currently recruiting, and 170 completed. 29 of these trials are in Phase 3-4 (later-stage) and 38 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 8 trials.

Top-decile sponsor footprint

University of Missouri-Columbia ranks in the top decile of sponsors by registered trial count (#120 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 29/100

170 of 224 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (75.9%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

291 total, page 3 of 6

COMPLETED

Experience With a Pediatric Summer Intensive Therapy Program

NCT04891328

COMPLETED NA

Resistance Training Effects on Gut Microbiome and Cardiometabolic Outcomes

NCT04906525

TERMINATED

Screening for Sacral Agenesis in Offspring of Mothers With Diabetes in Pregnancy

NCT05033275

COMPLETED Phase 4

A Randomized Trial of Exparel vs Saline in Opioid Reduction of Pain Management Following Lumbar Spine Surgeries.

NCT04644796

TERMINATED NA

n-3 Polyunsaturated Fatty Acids to Prevent and Treat Diabetic Neuropathy

NCT05145452

COMPLETED Phase 4

Methylnaltrexone vs Naloxegol in the Treatment of Opioid-Induced Constipation

NCT03523520

COMPLETED NA

Effects of a Personalized Diet on Cardiometabolic, Microbiome and Metabolomics Profiles in Minority Young Adults

NCT04635917

COMPLETED NA

Use of Traditional Curved Iris Scissors or the Wuennenberg Modified Curved Iris Scissors for Skin Surgery

NCT04413383

COMPLETED

Remote Neurocognitive and Psychological Assessment in PKU

NCT04943393

COMPLETED NA

Comparison and Outcomes of Endoscopic Ultrasound Liver Biopsies Versus Percutaneous Liver Biopsies

NCT04751045

COMPLETED NA

Feasibility Testing of Cognitive Strategy Training in Post-Concussive Syndrome

NCT04681742

COMPLETED Early Phase 1

Topical Tranexamic Acid Use on Granulating Wounds Following Mohs Micrographic Surgery

NCT04541303

COMPLETED Phase 1

Open Label Study: Treatment of ALS Fatigue With PolyMVA

NCT04557410

COMPLETED NA

Targeting the Carotid Bodies to Reduce Disease Risk Along the Diabetes Continuum

NCT05219994

COMPLETED NA

Endovascular Stroke Treatment Only (ESTO) Trial

NCT04240470

COMPLETED NA

Local Infiltration Analgesia Vs. Interscalene Block in Total Shoulder Arthorplasty

NCT04415931

COMPLETED Early Phase 1

Impact of Insulin on Sympathetic Nervous System-mediated Peripheral Vasoconstriction

NCT05244694

COMPLETED Phase 4

Bupivacaine for Post-operative Pain in Mohs

NCT04362566

COMPLETED Phase 3

Dornase Alfa for ARDS in Patients With Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2)

NCT04402970

COMPLETED NA

Computerized Cognitive Training in Middle-Aged Adults With Generalized Anxiety Disorder: A Pilot Study

NCT04421690

COMPLETED Phase 2

Perioperative Pregabalin in Ureteroscopy

NCT04122196

COMPLETED NA

Feasibility Trial of an Online Course (eMB) to Reduce Anxiety and Depression for Pregnant Women and Their Partners

NCT05867680

COMPLETED NA

Long Term Functional Outcomes of COVID-19 Patients Treated by Rehabilitation Services viaTelehealth

NCT04385901

COMPLETED

COVID-19 in Patients With HIV

NCT04333953

COMPLETED NA

Playing Cognitive Games For Older Adults With Insomnia

NCT04282642

COMPLETED NA

RTLS for Healthcare Process Validation

NCT04116957

TERMINATED Early Phase 1

Surgical Weight Loss and Alcohol Perception

NCT04299373

COMPLETED Phase 1

tDCS and CO-OP in Chronic Stroke

NCT04617548

COMPLETED NA

Metacognitive-Strategy Training in Sub-Acute Stroke

NCT04099511

TERMINATED NA

Impact of Exercise on Diastasis Rectus Abdominus

NCT04049487

COMPLETED NA

Examining the Effects of Neural Stimulation on Inhibitory Control and Cigarette Smoking

NCT03960138

COMPLETED NA

Maintenance Transcranial Magnetic Stimulation in Major Depressive Disorder

NCT04076644

COMPLETED NA

CBT-I on Alcohol Treatment Outcomes Among Veterans

NCT03806491

COMPLETED Phase 2

ENAC Blockade and Arterial Stiffness

NCT03837626

COMPLETED Early Phase 1

Ketogenic Diet for Traumatic Brain Injury

NCT03982602

COMPLETED Phase 4

The Use of Intranasal Calcitonin to Improve Pain and Activity in Elderly Pelvic Ring Injuries

NCT03812991

TERMINATED Phase 4

Differential Efficacy of Corticosteroid Solutions for Non-Operative Treatment of Digit Flexor Tenosynovitis

NCT04002037

TERMINATED NA

Non-operative vs Surgical Treatment of Isolated Non-Thumb Metacarpal Shaft Fractures

NCT04001062

TERMINATED NA

Feasibility of Better Living After Stroke Through Technology

NCT03935789

COMPLETED NA

Weight Stigma Effect on Neural Control of Appetite

NCT03934424

COMPLETED NA

The iTAP Study for Veterans

NCT03804788

COMPLETED Phase 3

Perioperative Pregabalin in Ureteroscopy: a Pilot

NCT03927781

TERMINATED Phase 4

Effect of Perioperative Intravenous Lidocaine Infusion in Robotic-Assisted Urologic Surgery

NCT03824808

COMPLETED NA

Sleep and Pain Interventions in Women With Fibromyalgia

NCT03744156

COMPLETED

De Novo Lipogenesis in Severity of NAFLD

NCT03683589

COMPLETED NA

The Effect of Kombucha on Blood Sugar Levels in Humans

NCT04051294

TERMINATED Phase 4

Effect of NSAID Use on Pain and Opioid Consumption Following Distal Radius Fracture

NCT03749616

COMPLETED

Indications for Osteochondral Allograft Transplantation

NCT03711747

COMPLETED Phase 4

Hyperosmolar Saline Irrigation Fluid in Arthroscopic Knee Surgery

NCT03564886

COMPLETED NA

Alcohol Impaired Driving: From the Laboratory to the Natural Environment

NCT03846050

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Phase Distribution

PhaseTrial count
Phase 1 26
Phase 2 12
Phase 3 4
Phase 4 25

What is open in the University of Missouri-Columbia pipeline

54 recruiting of 291 indexed (19% open); 170 completed (58%).

Phase mix: 29 late (III/IV) vs 38 early (I/II) (balanced across stages).

Top condition: Obesity (8 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

University of Missouri-Columbia: open-pipeline peers nationwide

Peers matched on 291 registered trials and 19% open enrollment, not the therapeutic-area sidebar.

University of Missouri-Columbia sits below the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0200400600 0%5%10%15%20% Total trials Recruiting share University of Missouri-ColumbiaThomas Jefferson UniversityUniversity of Michigan Rogel Cancer CenterKaiser PermanenteEisaiArkansas Children's Hospital Research InstituteMontefiore Medical CenterChildren's Hospital Medical Center, CincinnatiMclean Hospital
University of Missouri-Columbia sits below the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

University of Missouri-Columbia sits below the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 291 trials (± recruiting share)

Sponsors near 19% open enrollment (± trial volume)

What to do with this University of Missouri-Columbia page

291 registered trials is a research-attention snapshot, not an endorsement of University of Missouri-Columbia or any single study.

  • 54 of University of Missouri-Columbia's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Obesity is the condition University of Missouri-Columbia studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Obesity trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

University of Missouri-Columbia pipeline card: 291 registered trials from official public datasets.Report a data error.