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NCT03749616 · ClinicalTrials.gov registry record · Phase 4
Effect of NSAID Use on Pain and Opioid Consumption Following Distal Radius Fracture
A Phase 4 study, sponsored by University of Missouri-Columbia.
- Terminated
- Registry status
- Phase 4
- Development phase
- 32
- Enrollment target
NCT03749616: Clinical Trial Phase 4 study, sponsored by University of Missouri-Columbia.
NCT03749616 is a Phase 4 study that was terminated before completion, run by University of Missouri-Columbia. The registered enrollment target is 32 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (94% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03749616, a Phase 4 study, was terminated before completion, sponsored by University of Missouri-Columbia.
- TERMINATED
- Registry status
- Phase 4
- Development phase
- 32 participants
- Enrollment target
Study Summary
Non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, are excellent medications for providing pain control in certain patients. There is some data to suggest that NSAIDs can be used to reduce postoperative pain and narcotic use in patients who had undergone carpal tunnel release. There are mixed results about the effect of bone healing in adult patients with broken bones. The investigators hypothesize that NSAID administration in the acute phase of distal radius fracture healing will be non-inferior for pain control and decrease the use of opioid analgesics compared to patients who take acetaminophen for pain control during this same time period. Furthermore, the investigators hypothesize that patients will have similar or better patient reported outcomes, range of motion, and strength with the administration of NSAIDs.
Primary Outcome
The number and dosing of oxycodone tablets taken per participant for breakthrough pain will be recorded.
Interventions
- DRUG Acetaminophen
- DRUG Ibuprofen
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 32 participants |
| Start Date | 2019-01-02 |
| Est. Completion | 2022-03-24 |
| Phase | Phase 4 |
Why NCT03749616 stopped before completion
NCT03749616 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 32 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (94% lower).
The record links to 0 conditions, and to 2 interventions - of which Acetaminophen is the first listed.
NCT03749616 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03749616 about?
NCT03749616 is a clinical study titled "Effect of NSAID Use on Pain and Opioid Consumption Following Distal Radius Fracture". Non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, are excellent medications for providing pain control in certain patients. There is some data to suggest that NSAIDs can be used to reduce postoperative pain and narcotic use in patients who had undergone carpal tunnel release. There ...
What is the current status of trial NCT03749616?
This trial is currently terminated. It is a Phase 4 study. The enrollment target is 32 participants. The study started on 2019-01-02. Estimated completion is 2022-03-24.
What interventions are being tested in trial NCT03749616?
The interventions under investigation include: Acetaminophen (DRUG), Ibuprofen (DRUG).
Who is sponsoring clinical trial NCT03749616?
This trial is sponsored by University of Missouri-Columbia, which has 291 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03749616's enrollment target sits among peer trials
32 1534th of 2000 higher than 457 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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