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NCT04002037 · ClinicalTrials.gov registry record · Phase 4

Differential Efficacy of Corticosteroid Solutions for Non-Operative Treatment of Digit Flexor Tenosynovitis

A Phase 4 study, sponsored by University of Missouri-Columbia.

Terminated
Registry status
Phase 4
Development phase
95
Enrollment target

NCT04002037 is a Phase 4 study that was terminated before completion, run by University of Missouri-Columbia. The registered enrollment target is 95 participants.

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The verdict

NCT04002037, a Phase 4 study, was terminated before completion, sponsored by University of Missouri-Columbia.

TERMINATED
Registry status
Phase 4
Development phase
95 participants
Enrollment target

Study Summary

Trigger finger is a common cause of hand pain and dysfunction. Its due to chronic inflammation of the flexor tendon that leads to a pulley system mismatch. Historically it has been managed either conservatively with corticosteroid injections or through a surgical release of the A1 pulley. Several corticosteroids have been used for injection- dexamethasone, methylprednisolone, triamcinolone, betamethasone, paramethasone, etc. The purpose of out study is to determine if a 0.5 cc injection of Triamcinolone 40 mg/mL will be the most effective steroid injection for the non-surgical treatment. Approximately 200 subjects will be enrolled and randomized to one of three treatment arms: Triamcinolone 40mg/mL, Triamcinolone 10mg/mL and Soluble dexamethasone 4mg/mL. Treatment success will be defined as lack of conversion to surgical treatment, or no desire to proceed with surgery during study period (3 months).

Interventions

  • DRUG Triamcinolone Acetonide 40mg/mL
  • DRUG Triamcinolone Acetonide 10mg/mL
  • DRUG Dexamethasone 4 mg/ml

Trial Details

FieldValue
Enrollment Target 95 participants
Start Date 2019-06-25
Est. Completion 2023-01-01
Phase Phase 4

Sponsor

University of Missouri-Columbia

291 total trials

What the Registry Record Tells You About NCT04002037

The ClinicalTrials.gov registry entry for NCT04002037 describes a study currently listed as terminated, categorized as Phase 4. The registered enrollment target is 95 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Missouri-Columbia, which has 291 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Triamcinolone Acetonide 40mg/mL is the first listed.

NCT04002037 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04002037 about?

NCT04002037 is a clinical study titled "Differential Efficacy of Corticosteroid Solutions for Non-Operative Treatment of Digit Flexor Tenosynovitis". Trigger finger is a common cause of hand pain and dysfunction. Its due to chronic inflammation of the flexor tendon that leads to a pulley system mismatch. Historically it has been managed either conservatively with corticosteroid injections or through a surgical release of the A1 pulley. Several co...

What is the current status of trial NCT04002037?

This trial is currently terminated. It is a Phase 4 study. The enrollment target is 95 participants. The study started on 2019-06-25. Estimated completion is 2023-01-01.

What interventions are being tested in trial NCT04002037?

The interventions under investigation include: Triamcinolone Acetonide 40mg/mL (DRUG), Triamcinolone Acetonide 10mg/mL (DRUG), Dexamethasone 4 mg/ml (DRUG).

Who is sponsoring clinical trial NCT04002037?

This trial is sponsored by University of Missouri-Columbia, which has 291 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.