Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins sits in the top decile of US sponsors by registered trial count (#69 of 15,742 sponsors by registered trial count).

523 total trials 69 currently recruiting 301 completed early-phase tilt top decile by trial count

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins: 523 sponsored US clinical trials, 69 recruiting.

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins sponsors 523 registered US clinical trials on ClinicalTrials.gov, 69 of them currently recruiting, and 301 completed. 5 of these trials are in Phase 3-4 (later-stage) and 395 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Prostate Cancer, with 17 trials.

Top-decile sponsor footprint

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins ranks in the top decile of sponsors by registered trial count (#69 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 20/100

301 of 415 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (72.5%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

523 total, page 6 of 11

COMPLETED Phase 1

A Study of Metformin With or Without Rapamycin as Maintenance Therapy After Induction Chemotherapy in Subjects With Pancreatic Cancer

NCT02048384

TERMINATED Phase 1

Study of Rituximab and Brentuximab Vedotin for Relapsed Classical Hodgkin Lymphoma

NCT01900496

TERMINATED Phase 2

Detection and Prevention of Anthracycline-Related Cardiac Toxicity With Concurrent Simvastatin

NCT02096588

COMPLETED Early Phase 1

Lenalidomide, Dexamethasone and MEDI-551 in Untreated Multiple Myeloma

NCT01861340

COMPLETED Phase 1

Study of 18F-DCFPyL, a Second Generation Low-molecular Weight PSMA-based PET Radiotracer, in Patients With Prostate Cancer

NCT02151760

COMPLETED NA

A Comprehensive Smoking Cessation Intervention Duration Radiation for Upper Aerodigestive Cancers

NCT02188563

COMPLETED Phase 1

SGI-110 in Combination With an Allogeneic Colon Cancer Cell Vaccine (GVAX) and Cyclophosphamide (CY) in Metastatic Colorectal Cancer (mCRC)

NCT01966289

COMPLETED Phase 1

A Pre-surgical Study of LDE225 in Men With High-risk Localized Prostate Cancer

NCT02111187

COMPLETED Phase 1

Red Cell Transfusion Goals in Patients With Acute Leukemias

NCT02086773

COMPLETED Early Phase 1

A Study of Vismodegib in Men With Metastatic CRPC With Accessible Metastatic Lesions for Tumor Biopsy

NCT02115828

COMPLETED Phase 2

Trial to Improve Outcomes in Patients With Resected Pancreatic Cancer (Azacitidine)

NCT01845805

COMPLETED Phase 2

Stereotactic Body Radiation With Nelfinavir for Oligometastases

NCT01728779

COMPLETED Early Phase 1

A Pilot Study of Allopurinol As A Modifier of 6-MP Metabolism in Pediatric ALL

NCT02046694

TERMINATED Phase 2

Consolidation Therapy for Acute Myeloid Leukemia Guided by Leukemia Stem Cell Behavior

NCT01588951

COMPLETED Phase 2

Phase II Anti-PD1 Epigenetic Therapy Study in NSCLC.

NCT01928576

COMPLETED Phase 2

FOLFIRINOX Followed by Ipilimumab With Pancreatic Tumor Vaccine in Treatment of Metastatic Pancreatic Cancer

NCT01896869

COMPLETED NA

Stereotactic Radiation Therapy for Pediatric Sarcomas

NCT01763970

COMPLETED Phase 1

Phase I/II Study of SGI-110 With Irinotecan Versus Regorafenib or TAS-102 in Metastatic Colorectal Cancer

NCT01896856

COMPLETED

Tumor Motion Management in Radiotherapy Using 4D-MRI

NCT01934855

TERMINATED Phase 1

Allogeneic Human Bone Marrow Derived Mesenchymal Stem Cells in Localized Prostate Cancer

NCT01983709

COMPLETED NA

IMAGE Study: Personalized Molecular Profiling in Cancer Treatment at Johns Hopkins

NCT01939847

COMPLETED Phase 2

Study of MK-3475 in Patients With Microsatellite Unstable (MSI) Tumors (Cohorts A, B and C)

NCT01876511

COMPLETED Phase 2

Tadalafil and Lenalidomide Maintenance With or Without Activated Marrow Infiltrating Lymphocytes (MILs) in High Risk Myeloma

NCT01858558

TERMINATED Phase 1

SRS (Stereotactic Radiosurgery) Plus Ipilimumab

NCT01950195

TERMINATED Phase 2

Combination of External Beam Radiotherapy With 153Sm-EDTMP to Treat High Risk Osteosarcoma

NCT01886105

COMPLETED NA

Robot-Assisted MRI-Guided Prostate Biopsy

NCT02080052

COMPLETED NA

POWER-remote Weight Loss Program in Early Stage Breast Cancer

NCT01871116

COMPLETED Phase 2

Phase II Study of Azacitidine and Sargramostim as Maintenance Treatment for Poor-Risk AML or MDS

NCT01700673

COMPLETED Early Phase 1

Optimized Antiretroviral Therapy During Allogeneic Hematopoietic Stem Cell Transplantation in HIV-1 Individuals

NCT01836068

COMPLETED Phase 1

Radiation and Androgen Ablation for Prostate Cancer

NCT01517451

COMPLETED Phase 2

Radiotherapy for Solid Tumor Spine Metastases

NCT01752036

COMPLETED Phase 1

Mebendazole in Newly Diagnosed High-Grade Glioma Patients Receiving Temozolomide

NCT01729260

COMPLETED NA

Hippocampal Prophylactic Cranial Irradiation for Small Cell Lung Cancer

NCT01797159

COMPLETED Phase 1

Intra-arterial Chemotherapy for the Treatment of Progressive Diffuse Intrinsic Pontine Gliomas (DIPG).

NCT01688401

COMPLETED Phase 1

Evaluation of 18F-DCFBC PSMA-based PET Imaging for Detection of Metastatic Prostate Cancer

NCT01815515

TERMINATED Phase 2

A Randomized Phase II Study of SUBATM-itraconazole in Patients With Untreated Squamous NSCLC.

NCT01752023

COMPLETED Early Phase 1

Group Intervention to Increase Physical Activity in Childhood Cancer Survivors

NCT01835509

COMPLETED Phase 1

A Neoadjuvant Study of Androgen Ablation Combined With Cyclophosphamide and GVAX Vaccine for Localized Prostate Cancer

NCT01696877

COMPLETED Phase 2

Palliative Stereotactic Radiation for Pancreatic or Periampullary Adenocarcinoma

NCT01781728

COMPLETED Phase 2

DIG-HIF-1 Pharmacodynamic Trial in Newly Diagnosed Operable Breast Cancer

NCT01763931

COMPLETED Phase 2

Bipolar Androgen-based Therapy for Prostate Cancer (BAT)

NCT01750398

COMPLETED Phase 2

Phase II Study Using CHFR Methylation Status in Patients With Metastatic Esophageal, Gastroesophageal, Gastric Cancer.

NCT01715233

TERMINATED Phase 1

A Phase I/II Study Afatinib/Carboplatin/Paclitaxel Induction Chemotherapy In HPV-Negative HNSCC.

NCT01732640

COMPLETED Phase 2

Pancreatic Tumor Cell Vaccine (GVAX), Cyclophosphamide, SBRT, and FOLFIRINOX in Patients With Resected Adenocarcinoma of the Pancreas

NCT01595321

COMPLETED Phase 1

Evaluation of Prostate-specific Membrane Antigen (PSMA)-Based PET Imaging of Primary Prostate Cancer

NCT01496157

TERMINATED Phase 2

Gemcitabine and Docetaxel in Patients With Relapsed or Refractory Metastatic Colorectal Adenocarcinoma

NCT01639131

COMPLETED Phase 2

Low Dose Radiation Therapy for Glioblastoma Multiforme

NCT01466686

COMPLETED Phase 2

Maintenance Rituximab With mTor Inhibition After High-dose Consolidative Therapy in Lymphoma

NCT01665768

COMPLETED Phase 2

A Phase II Trial of Tadalafil in Patients With Squamous Cell Carcinoma of the Upper Aero Digestive Tract

NCT01697800

TERMINATED Phase 1

Phase I Study of Orally Administered Aminolevulinic Acid for Resection of Malignant Astrocytomas

NCT01502605

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What is open in the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins pipeline

69 recruiting of 523 indexed (13% open); 301 completed (58%).

Phase mix: 5 late (III/IV) vs 395 early (I/II) (early-phase heavy).

Top condition: Prostate Cancer (17 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins: open-pipeline peers nationwide

Peers matched on 523 registered trials and 13% open enrollment, not the therapeutic-area sidebar.

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0200400600 0%5%10%15%20%25% Total trials Recruiting share Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsAbbVieBoehringer IngelheimGilead SciencesH. Lee Moffitt Cancer Center and Research InstituteMetroHealth Medical CenterTexas Tech University Health Sciences CenterChiesi Farmaceutici S.p.A.Dizal Pharmaceuticals
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 523 trials (± recruiting share)

Sponsors near 13% open enrollment (± trial volume)

What to do with this Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins page

523 registered trials is a research-attention snapshot, not an endorsement of Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins or any single study.

  • 69 of Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Prostate Cancer is the condition Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Prostate Cancer trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins pipeline card: 523 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.