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NCT01966289 · ClinicalTrials.gov registry record · Phase 1
SGI-110 in Combination With an Allogeneic Colon Cancer Cell Vaccine (GVAX) and Cyclophosphamide (CY) in Metastatic Colorectal Cancer (mCRC)
A Phase 1 study of Metastatic Colorectal Cancer, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.
- Completed
- Registry status
- Phase 1
- Development phase
- 18
- Enrollment target
- 1
- Study location
NCT01966289: Completed Phase 1 study of Metastatic Colorectal Cancer, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.
NCT01966289 is a Phase 1 study of Metastatic Colorectal Cancer that has completed, run by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. The registered enrollment target is 18 participants, below the 186-participant average among 45 other Metastatic Colorectal Cancer trials with a reported enrollment target (90% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01966289, a Phase 1 study of Metastatic Colorectal Cancer, has completed, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 18 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will be looking at whether CY/GVAX in combination with SGI-110 is effective (recruits CD45RO+ T cells to the tumor which may be a marker of anti-tumor activity) and safe in patients with metastatic colon or rectum cancers.
Conditions Studied
Interventions
- DRUG CY
- BIOLOGICAL GVAX
- DRUG SGI-110
Study Locations (1)
Maryland
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 18 participants |
| Start Date | 2014-04-14 |
| Est. Completion | 2020-06-06 |
| Phase | Phase 1 |
What the finished NCT01966289 record still lists
NCT01966289 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 18 participants, a relatively small participant target, below the 186-participant average among 45 other Metastatic Colorectal Cancer trials with a reported enrollment target (90% lower).
The record links to 1 condition, with Metastatic Colorectal Cancer appearing as the primary indexed condition, and to 3 interventions - of which CY is the first listed.
NCT01966289 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT01966289 about?
NCT01966289 is a clinical study titled "SGI-110 in Combination With an Allogeneic Colon Cancer Cell Vaccine (GVAX) and Cyclophosphamide (CY) in Metastatic Colorectal Cancer (mCRC)". This study will be looking at whether CY/GVAX in combination with SGI-110 is effective (recruits CD45RO+ T cells to the tumor which may be a marker of anti-tumor activity) and safe in patients with metastatic colon or rectum cancers.
What is the current status of trial NCT01966289?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 18 participants. The study started on 2014-04-14. Estimated completion is 2020-06-06.
What conditions does trial NCT01966289 study?
This clinical trial studies the following conditions: Metastatic Colorectal Cancer.
What interventions are being tested in trial NCT01966289?
The interventions under investigation include: CY (DRUG), GVAX (BIOLOGICAL), SGI-110 (DRUG).
Who is sponsoring clinical trial NCT01966289?
This trial is sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, which has 523 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01966289 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT01966289's enrollment target sits among peer trials
18 43rd of 45 higher than 3 of 45 other Metastatic Colorectal Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Metastatic Colorectal Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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