Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins sits in the top decile of US sponsors by registered trial count (#69 of 15,742 sponsors by registered trial count).

523 total trials 69 currently recruiting 301 completed early-phase tilt top decile by trial count

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins: 523 sponsored US clinical trials, 69 recruiting.

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins sponsors 523 registered US clinical trials on ClinicalTrials.gov, 69 of them currently recruiting, and 301 completed. 5 of these trials are in Phase 3-4 (later-stage) and 395 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Prostate Cancer, with 17 trials.

Top-decile sponsor footprint

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins ranks in the top decile of sponsors by registered trial count (#69 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 20/100

301 of 415 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (72.5%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

523 total, page 7 of 11

TERMINATED Phase 1

A Phase 1 Trial of TST of PD 0332991 Followed by Cytarabine and Mitoxantrone for Adults With Relapsed and Refractory Acute Leukemias and High-Risk Myelodysplasia

NCT01701375

COMPLETED NA

Prospective Evaluation of T-cell Immune Status in Patients With Newly Diagnosed High Grade Gliomas

NCT02041611

TERMINATED NA

Pre-Prostatectomy Lovastatin on Prostate Cancer

NCT01478828

COMPLETED NA

Feasibility of Lymphocyte Reinfusion in Newly Diagnosed High Grade Gliomas

NCT01653834

COMPLETED Phase 1

Mibefradil Dihydrochloride and Temozolomide in Treating Patients With Recurrent Glioma

NCT01480050

COMPLETED

Johns Hopkins Breast Cancer Program Hormone Therapy Longitudinal Database

NCT01937052

TERMINATED Phase 2

Study of Metformin Plus Paclitaxel/Carboplatin/Bevacizumab in Patients With Adenocarcinoma.

NCT01578551

COMPLETED Early Phase 1

PET Quantitative Assessments of Solid Tumor Response to Immune Checkpoint Blockade Therapy

NCT01666353

TERMINATED Phase 1

Safety Study of HPV DNA Vaccine to Treat Head and Neck Cancer Patients

NCT01493154

TERMINATED Phase 2

Administration of Tadalafil in Conjunction With Lenalidomide and Dexamethasone in Patients With Multiple Myeloma

NCT01374217

COMPLETED Phase 1

A Trial of Oral 5-azacitidine in Combination With Romidepsin in Advanced Solid Tumors, With an Expansion Cohort in Virally Mediated Cancers and Liposarcoma

NCT01537744

COMPLETED Phase 2

Allogeneic GM-CSF Vaccine and Lenalidomide in Treating Myeloma Patients With Near Complete Remission

NCT01349569

TERMINATED NA

A Feasibility Study of a Modular Video Augmentation System for Image-Guided Skull Base Surgery

NCT01591954

COMPLETED NA

Neural Progenitor Cell Sparing Radiation Therapy Plus Temozolomide

NCT01478854

TERMINATED Phase 1

Gemcitabine + Nab-paclitaxel With LDE-225 (Hedgehog Inhibitor) as Neoadjuvant Therapy for Pancreatic Adenocarcinoma

NCT01431794

COMPLETED Phase 2

Gemcitabine/Taxotere/Xeloda (GTX) With Cisplatin in Subjects With Metastatic Pancreatic Cancer

NCT01459614

COMPLETED Phase 1

Phase 1 Study of Pazopanib With GSK1120212 in Advanced Solid Tumors, Enriched With Patients With Differentiated Thyroid Cancer, Soft-tissue Sarcoma, and Cholangiocarcinoma

NCT01438554

COMPLETED Phase 1

Safety Study of a Melanoma Vaccine (GVAX) With or Without Cyclophosphamide in Patients With Surgically Resected Melanoma

NCT01435499

TERMINATED NA

Decision Support for Women With Breast Cancer

NCT01447771

COMPLETED Phase 1

Shorter Course Tacrolimus After Nonmyeloablative, Related Donor BMT With High-dose Posttransplantation Cyclophosphamide

NCT01342289

COMPLETED Phase 1

Effects of Two Doses of MPX Capsules on Rising Prostate-specific Antigen Levels in Men Following Initial Therapy for Prostate Cancer

NCT01317199

COMPLETED

Endothelial Function, Arterial Stiffness and Components

NCT01439217

TERMINATED Phase 2

CHFR Methylation Status Esophageal Cancer Study

NCT01372202

TERMINATED Phase 2

Bone Marrow Transplant Trial for Patients With Refractory Severe Aplastic Anemia

NCT01383434

COMPLETED Phase 1

Evaluation of a Transrectal Scintigraphic Detector(ProxiScanTM) for Detection of Primary Prostate Cancer

NCT01359189

TERMINATED Phase 2

Patient-donor Vaccination in the Context of Allogeneic Bone Marrow Transplant With Post-transplant Cyclophosphamide

NCT01282216

TERMINATED Phase 2

A Study of Vorinostat and Tamoxifen in Newly Diagnosed Breast Cancer

NCT01194427

TERMINATED Phase 2

Intra-arterial Chemotherapy for the Treatment of Intraocular Retinoblastoma

NCT01293539

COMPLETED Phase 2

Zoledronic Acid in Aromatase Inhibitor Induced Musculoskeletal Symptoms

NCT01194440

COMPLETED Phase 1

Trial of ICM With or Without AZD2281 (Olaparib) in Patients With Advanced Pancreatic Cancer

NCT01296763

COMPLETED NA

124I-FIAU Imaging in EBV and KSHV Associated Cancers

NCT00982449

COMPLETED NA

Study of High-Dose-Rate Endorectal Brachytherapy (HDRBT) in the Treatment of Locally Advanced Low Rectal Cancer

NCT01226979

COMPLETED Phase 2

Hedgehog Inhibitors for Metastatic Adenocarcinoma of the Pancreas

NCT01088815

COMPLETED Phase 1

Reduced Intensity, Partially HLA Mismatched BMT to Treat Hematologic Malignancies

NCT01203722

COMPLETED Phase 1

Biodistribution and Pharmacokinetic Study of 18F-DCFBC Prostate Specific Membrane Antigen Based PET in Patients With Advanced Prostate Cancer

NCT01417182

TERMINATED Phase 2

Reduced-intensity, Related-donor Bone Marrow Transplantation Followed by High-dose Cyclophosphamide for Hematologic Cancers

NCT01135329

COMPLETED Phase 2

Ramucirumab or Anti-PDGFR Alpha Monoclonal Antibody IMC-3G3 in Treating Patients With Recurrent Glioblastoma Multiforme

NCT00895180

COMPLETED NA

Study of Recurrent Prostate Cancer With Rising Prostate Specific Antigen (PSA)

NCT01118741

COMPLETED Phase 2

Treatment De-Intensification for Squamous Cell Carcinoma of the Oropharynx

NCT01088802

COMPLETED NA

A Pilot Study of Parenteral Testosterone and Oral Etoposide as Therapy for Men With Castration Resistant Prostate Cancer

NCT01084759

TERMINATED NA

An Early Safety and Efficacy Study of Ascites Management: Standard Paracentesis or Early Intervention With Pleurx Catheters in Patients With Malignant Ascites

NCT01077063

COMPLETED Phase 2

Trial of Activated Marrow Infiltrating Lymphocytes Alone or in Conjunction With an Allogeneic Granulocyte Macrophage Colony-stimulating Factor (GM-CSF)-Based Myeloma Cellular Vaccine in the Autologous Transplant Setting in Multiple Myeloma

NCT01045460

COMPLETED NA

Cytokine Expression During Radiation for Breast Cancer

NCT00836186

TERMINATED Phase 1

RAD001 in Combination With Cetuximab and Cisplatin in Recurrent and Metastatic SCCHN

NCT01009346

COMPLETED

Using High Resolution Function Imaging To Detect Melanoma and Dysplastic Nevi

NCT01118832

COMPLETED Phase 1

Therapeutic Vaccination for Patients With HPV16+ Cervical Intraepithelial Neoplasia (CIN2/3)

NCT00988559

COMPLETED Phase 1

Safety and Efficacy Study of Torisel and Liposomal Doxorubicin for Patients With Recurrent Sarcoma

NCT00949325

COMPLETED Phase 1

ABT-888, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

NCT00770471

COMPLETED Phase 2

Cyclophosphamide and Vaccine Therapy With or Without Trastuzumab in Treating Patients With Metastatic Breast Cancer

NCT00971737

TERMINATED Phase 2

Optimized Donor Selection, Nonmyeloablative BMT for B-cell Lymphomas With Post-transplantation Cy and Rituximab

NCT00946023

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What is open in the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins pipeline

69 recruiting of 523 indexed (13% open); 301 completed (58%).

Phase mix: 5 late (III/IV) vs 395 early (I/II) (early-phase heavy).

Top condition: Prostate Cancer (17 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins: open-pipeline peers nationwide

Peers matched on 523 registered trials and 13% open enrollment, not the therapeutic-area sidebar.

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0200400600 0%5%10%15%20%25% Total trials Recruiting share Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsAbbVieBoehringer IngelheimGilead SciencesH. Lee Moffitt Cancer Center and Research InstituteMetroHealth Medical CenterTexas Tech University Health Sciences CenterChiesi Farmaceutici S.p.A.Dizal Pharmaceuticals
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 523 trials (± recruiting share)

Sponsors near 13% open enrollment (± trial volume)

What to do with this Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins page

523 registered trials is a research-attention snapshot, not an endorsement of Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins or any single study.

  • 69 of Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Prostate Cancer is the condition Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Prostate Cancer trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins pipeline card: 523 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.