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NCT01797159 · ClinicalTrials.gov registry record · NA
Hippocampal Prophylactic Cranial Irradiation for Small Cell Lung Cancer
A NA study of Small-cell Lung Cancer and SCLC, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.
- Completed
- Registry status
- NA
- Development phase
- 20
- Enrollment target
- 2
- Study locations
NCT01797159: Completed NA study of Small-cell Lung Cancer and SCLC, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.
NCT01797159 is a NA study of Small-cell Lung Cancer and SCLC that has completed, run by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. The registered enrollment target is 20 participants, below the 232-participant average among 79 other Small-cell Lung Cancer trials with a reported enrollment target (91% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01797159, a NA study of Small-cell Lung Cancer and SCLC, has completed, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.
- COMPLETED
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
- 2
- Study locations
Study Summary
The Investigators are looking to compare standard treatment for the management of small cell lung cancer (SCLC) which is prophylactic cranial Irradiation (PCI) (shown to be very good in patient survival) with cranial sparing PCI. Although standard of care PCI is successful in patient survival it also has neurologic side-effects. The Investigators are hoping the cranial sparing PCI has the same positive survival results with the added benefit of lowering neurological side-effects.
Primary Outcome
The primary endpoint of this study is cognitive function or memory. Memory is measured by participant performance on the Hopkins Verbal Learning Test-Revised for delayed recall (HVLT-R-Delayed Recall) at 6 months following hippocampal-sparing PCI. The HVLT-Delayed minimum and Maximum scores are 0-12. A higher score means a better outcome.
Conditions Studied
Interventions
- RADIATION Hippocampal-sparing Prophylactic Cranial Irradiation
Study Locations (2)
Maryland
- Bayview Medical Center - Baltimore
- The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2013-03-11 |
| Est. Completion | 2019-03-18 |
| Phase | NA |
What the finished NCT01797159 record still lists
NCT01797159 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 232-participant average among 79 other Small-cell Lung Cancer trials with a reported enrollment target (91% lower).
The record links to 3 conditions, with Small-cell Lung Cancer appearing as the primary indexed condition, and to 1 intervention - of which Hippocampal-sparing Prophylactic Cranial Irradiation is the first listed.
NCT01797159 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT01797159 about?
NCT01797159 is a clinical study titled "Hippocampal Prophylactic Cranial Irradiation for Small Cell Lung Cancer". The Investigators are looking to compare standard treatment for the management of small cell lung cancer (SCLC) which is prophylactic cranial Irradiation (PCI) (shown to be very good in patient survival) with cranial sparing PCI. Although standard of care PCI is successful in patient survival it als...
What is the current status of trial NCT01797159?
This trial is currently completed. It is a NA study. The enrollment target is 20 participants. The study started on 2013-03-11. Estimated completion is 2019-03-18.
What conditions does trial NCT01797159 study?
This clinical trial studies the following conditions: Small-cell Lung Cancer, SCLC, Small Cell Lung Cancer Limited Stage.
What interventions are being tested in trial NCT01797159?
The interventions under investigation include: Hippocampal-sparing Prophylactic Cranial Irradiation (RADIATION).
Who is sponsoring clinical trial NCT01797159?
This trial is sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, which has 523 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01797159 being conducted?
This trial has 2 study locations across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Small-cell Lung Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01797159's enrollment target sits among peer trials
20 75th of 79 higher than 3 of 79 other Small-cell Lung Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Small-cell Lung Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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