Rush University Medical Center

Open enrollment across a mixed-phase pipeline

According to ClinicalTrials.gov-derived indexes, Rush University Medical Center sits in the top decile of US sponsors by registered trial count (#112 of 15,742 sponsors by registered trial count).

320 total trials 53 currently recruiting 206 completed top decile by trial count

Rush University Medical Center: 320 sponsored US clinical trials, 53 recruiting.

Rush University Medical Center sponsors 320 registered US clinical trials on ClinicalTrials.gov, 53 of them currently recruiting, and 206 completed. 42 of these trials are in Phase 3-4 (later-stage) and 41 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Total Knee Arthroplasty, with 3 trials.

Top-decile sponsor footprint

Rush University Medical Center ranks in the top decile of sponsors by registered trial count (#112 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 51/100

206 of 244 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (84.4%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

320 total, page 4 of 7

COMPLETED Phase 1

Potential for Cortisol Suppression With the Use of High Volume Nasal Mometasone Irrigations in Varying Dosages.

NCT03979209

COMPLETED NA

A Small Changes Weight Loss Program and Message Dissemination Via Facebook in Chicago's West Side

NCT03614338

COMPLETED NA

The Effects of Flow Settings During High Flow Nasal Cannula for Adult Hypoxemia Patients

NCT03738345

COMPLETED

FLXfitTM 15 TLIF Interbody Fusion Device

NCT04208048

TERMINATED NA

Effect of Catheter on Postoperative Urinary Retention

NCT04645264

COMPLETED

Fecal Microbiota Transplantation (FMT) in Multiple Sclerosis

NCT03975413

COMPLETED NA

Testing Adaptive Interventions to Improve Physical Activity for Sedentary Women

NCT03558828

COMPLETED NA

Device-Based Scribe Service (iScribes) on Patient Satisfaction

NCT03854955

COMPLETED NA

Impacting the Disposal of Unused Opioid

NCT04044105

COMPLETED

Levodopa Response and Gut Microbiome in Patients With Parkinson's Disease

NCT04956939

COMPLETED NA

Study of an Orthotic Designed to Equalize Leg Lengths for Patients With Injuries Managed in Walking Boots

NCT03848949

COMPLETED NA

The Impact of High-Flow Nasal Cannula on Swallow Function

NCT03590457

COMPLETED NA

Kick Out Parkinson's Disease- Karate Intervention

NCT03555695

COMPLETED NA

In-Home Care for Patients With PSP and Related Disorders

NCT03552484

COMPLETED NA

In-Home Care for Patients With Parkinson's Disease

NCT03189459

COMPLETED

Assessing Respiratory Rate and Tidal Volume Delivery During Manual Ventilation

NCT03544164

COMPLETED

Targeting Diet-Microbiome Interactions in the Pathogenesis of Parkinson's Disease

NCT03705520

COMPLETED

The Accuracy of Smartphone Pulse Oximetry in Patients Visiting an Outpatient Pulmonary Function Lab for a 6-Minute Walk Test

NCT03534271

COMPLETED NA

Noninvasive Ventilation Masks Carbon Dioxide Clearance in Normal Volunteers

NCT03882723

COMPLETED NA

Autologous Bone Marrow Concentrate in Knee Osteochondral Allograft Transplantation

NCT04739930

COMPLETED NA

Examining an Adaptive Telehealth Intervention

NCT03840642

COMPLETED

Surpoint Algorithm for Improved Guidance of Ablation for Ventricular Tachycardia

NCT05618717

COMPLETED NA

Homeless Youth Study - Stepping Stone 2.0

NCT03776422

COMPLETED

Effect of Body Position on Spirometry in Abdominal Obesity.

NCT03347604

COMPLETED Phase 3

Aprepitant- and Olanzapine- Containing Anti-emetic Regimens With High Dose Melphalan

NCT02939287

COMPLETED NA

Single-Level TLIF: Post-Fusion Rehabilitation

NCT03033212

COMPLETED NA

Creating Healthy Environments for Chicago Kids

NCT03195790

COMPLETED

Determining the Microbiota Composition of the Middle Meatus in Parkinson's

NCT03336697

COMPLETED Phase 4

Comparing Opioid Prescription Patterns in Total Joint Arthroplasty Patients

NCT03236155

COMPLETED Phase 1

Comparison of Negative Pressure Wound Therapy vs. Conventional Dressings for Prevention of Wound Complications After Revision THA

NCT03321799

COMPLETED NA

Post-Bariatric Weight Regain Behavioral Intervention

NCT03564392

TERMINATED NA

Humidity Therapy for Spontaneously Breathing Tracheostomy Patients

NCT02686489

COMPLETED NA

Effect of Sleep on the Recovery of Patients Admitted to the ICU

NCT04111900

COMPLETED NA

Fermented Milk Product With Probiotic and Its Impact on Mood of Patients With Treatment Resistant Depression

NCT03317678

COMPLETED

The Role of suPAR Biomarker in Blood Samples of Breast Cancer Patients During and Post Doxorubicin Chemotherapy: Causative vs. Predictor

NCT03505164

COMPLETED NA

Teen Sleep Health Study

NCT04087603

COMPLETED NA

MIND Diet Intervention and Cognitive Decline

NCT02817074

COMPLETED Phase 4

The Relationship Among Changes in Brain Network Activation in Adult Outpatients With Major Depressive Disorder

NCT02749721

COMPLETED

Circadian Misalignment in Inflammatory Bowel Disease

NCT04637399

COMPLETED NA

Educational Intervention to Improve Patient-Physician Awareness of Cardiovascular Risk in Rheumatoid Arthritis.

NCT03495791

COMPLETED NA

Using Pressure Detecting Insoles to Reduce Knee Loading

NCT02955225

COMPLETED NA

Ambulation Versus Standing on Postoperative Day 0

NCT02879188

COMPLETED NA

Steps to Effective Problem Solving in Group Homes

NCT02855008

COMPLETED

Evaluating the Effect of Chronic Antihypertensive Therapy on Vasopressor Dosing in Septic Shock

NCT02884011

COMPLETED NA

Formal vs. Home-Based Physical Therapy After Unicompartmental Knee Arthroplasty

NCT02883998

COMPLETED

Effects of Chronic Antihypertensive Therapy on Clinical Outcomes in Septic Shock

NCT02876341

COMPLETED Phase 2

Oxytocin and Social Cognitive Skills Groups

NCT02918864

TERMINATED NA

Memory Training in Aneurysmal Subarachnoid Hemorrhage Patients

NCT02864940

COMPLETED NA

Preventative Delirium Protocol in Elderly Patients

NCT03541408

COMPLETED Phase 4

Chronotherapy in Inflammatory Bowel Disease

NCT04304950

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Phase Distribution

PhaseTrial count
Phase 1 16
Phase 2 25
Phase 3 6
Phase 4 36

What is open in the Rush University Medical Center pipeline

53 recruiting of 320 indexed (17% open); 206 completed (64%).

Phase mix: 42 late (III/IV) vs 41 early (I/II) (balanced across stages).

Top condition: Total Knee Arthroplasty (3 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Rush University Medical Center: open-pipeline peers nationwide

Peers matched on 320 registered trials and 17% open enrollment, not the therapeutic-area sidebar.

Rush University Medical Center sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,5002,0002,500 0%5%10%15%20% Total trials Recruiting share Rush University Medical CenterJonsson Comprehensive Cancer CenterUniversity of ArkansasAllerganGenentechOHSU Knight Cancer InstituteMassachusetts General HospitalAdageneAgendia
Rush University Medical Center sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Rush University Medical Center sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 320 trials (± recruiting share)

Sponsors near 17% open enrollment (± trial volume)

What to do with this Rush University Medical Center page

320 registered trials is a research-attention snapshot, not an endorsement of Rush University Medical Center or any single study.

  • 53 of Rush University Medical Center's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Total Knee Arthroplasty is the condition Rush University Medical Center studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Total Knee Arthroplasty trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Rush University Medical Center pipeline card: 320 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.