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NCT03317678 · ClinicalTrials.gov registry record · NA
Fermented Milk Product With Probiotic and Its Impact on Mood of Patients With Treatment Resistant Depression
A NA study, sponsored by Rush University Medical Center.
- Completed
- Registry status
- NA
- Development phase
- 40
- Enrollment target
NCT03317678: Completed NA study, sponsored by Rush University Medical Center.
NCT03317678 is a NA study that has completed, run by Rush University Medical Center. The registered enrollment target is 40 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03317678, a NA study, has completed, sponsored by Rush University Medical Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 40 participants
- Enrollment target
Study Summary
This study aims to assess the impact of a chronic dietary intervention (8 weeks) with probiotics, specifically Fermented Milk Product with Probiotic (FMPP), on the mood of individuals with Major Depressive Disorder (MDD) refractory to standard antidepressant therapy, and its association with changes in intestinal microbiota and markers of inflammation.
Primary Outcome
The primary outcome measure will be change in the Montgomery-Åsberg Depression Rating Scale (MADRS). The MADRS is a 10-item scale for the evaluation of depressive symptoms (Montgomery \& Åsberg, 1979).
Interventions
- DIETARY_SUPPLEMENT BioKefir
- DIETARY_SUPPLEMENT Non-fermented milk
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2017-02-10 |
| Est. Completion | 2022-12-07 |
| Phase | NA |
What the finished NCT03317678 record still lists
NCT03317678 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 2 interventions - of which BioKefir is the first listed.
NCT03317678 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03317678 about?
NCT03317678 is a clinical study titled "Fermented Milk Product With Probiotic and Its Impact on Mood of Patients With Treatment Resistant Depression". This study aims to assess the impact of a chronic dietary intervention (8 weeks) with probiotics, specifically Fermented Milk Product with Probiotic (FMPP), on the mood of individuals with Major Depressive Disorder (MDD) refractory to standard antidepressant therapy, and its association with changes...
What is the current status of trial NCT03317678?
This trial is currently completed. It is a NA study. The enrollment target is 40 participants. The study started on 2017-02-10. Estimated completion is 2022-12-07.
What interventions are being tested in trial NCT03317678?
The interventions under investigation include: BioKefir (DIETARY_SUPPLEMENT), Non-fermented milk (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT03317678?
This trial is sponsored by Rush University Medical Center, which has 320 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03317678's enrollment target sits among peer trials
40 1447th of 2000 higher than 465 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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