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NCT05618717 · ClinicalTrials.gov registry record

Surpoint Algorithm for Improved Guidance of Ablation for Ventricular Tachycardia

A clinical trial, sponsored by Rush University Medical Center.

Completed
Registry status
103
Enrollment target

NCT05618717: Completed study, sponsored by Rush University Medical Center.

NCT05618717 is a clinical trial that has completed, run by Rush University Medical Center. The registered enrollment target is 103 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05618717 has completed, sponsored by Rush University Medical Center.

COMPLETED
Registry status
103 participants
Enrollment target

Study Summary

Vistag SurPoint is a proprietary module that generates a numerical tag index which can be used as multiparametric lesion quality marker to guide ablation in the clinical setting for ablation of atrial arrhythmias. SurPoint tag index has studied to guide ablation of ventricular arrhythmias, such as premature ventricular complexes, but its effectiveness and safety for ablation of Ventricular Tachycardia in patient with Ischemic and Non-Ischemic Cardiomyopathies is not well established. In this single center prospective observation registry, a ventricular ablation strategy utilizing radiofrequency delivery duration cut off determined by a maximum Surpoint index value of 550 will be compared to conventional operator determined duration of radiofrequency delivery based on combination of time (i.e. 30, 60, 90, and 120 seconds), magnitude of impedance drop, attenuation of abnormal electrograms, and achieving non-capture with high-output pacing after ablation. The Surpoint Tag Index Ablation group will be matched with a control group of patients undergoing VT ablation using the conventional time-based radiofrequency strategy and the patients in this group will be selected using propensity matching based on relevant baseline patient and clinical characteristic variables. Primary outcomes of interest: Recurrence of sustained ventricular tachycardia or Internal Cardiac Defibrillator Therapy. Secondary outcomes of interest: Hospitalization for ventricular tachycardia, repeat ablation procedures, all-cause mortality, acute procedural complications, rate of steam pops during ablation procedures Follow up: Up to 24 months after ablation procedure. Follow up will be obtained by office visits and device interrogation reports.

Primary Outcome

Composite outcome of sustained ventricular tachycardia (episode lasting \> 30 seconds detected by ICD) or ventricular tachycardia episode treated successfully by ICD therapy (Including ventricular tachycardia episodes terminated by ATP or ICD shock in \< 30 seconds based programmed detection/treatment ICD settings)

Interventions

  • DEVICE Radiofrequency Ablation

Trial Details

FieldValue
Enrollment Target 103 participants
Start Date 2018-01-01
Est. Completion 2023-01-31
Rush University Medical Center

320 total trials

What the finished NCT05618717 record still lists

NCT05618717 is an observational study that tracks outcomes without assigning an intervention. The registered 103 participants enrollment target is mid-sized for trials with a published cap.

The record links to 0 conditions, and to 1 intervention - of which Radiofrequency Ablation is the first listed.

NCT05618717 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT05618717 about?

NCT05618717 is a clinical study titled "Surpoint Algorithm for Improved Guidance of Ablation for Ventricular Tachycardia". Vistag SurPoint is a proprietary module that generates a numerical tag index which can be used as multiparametric lesion quality marker to guide ablation in the clinical setting for ablation of atrial arrhythmias. SurPoint tag index has studied to guide ablation of ventricular arrhythmias, such as p...

What is the current status of trial NCT05618717?

This trial is currently completed. The enrollment target is 103 participants. The study started on 2018-01-01. Estimated completion is 2023-01-31.

What interventions are being tested in trial NCT05618717?

The interventions under investigation include: Radiofrequency Ablation (DEVICE).

Who is sponsoring clinical trial NCT05618717?

This trial is sponsored by Rush University Medical Center, which has 320 total clinical trials registered on ClinicalTrials.gov.

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Source: ClinicalTrials.gov NCT05618717, the US trial registry maintained by the National Library of Medicine. NCT05618717 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.