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2026 data Public-data reference. official source

Dementia With Lewy Bodies

Open-data reference.

23 US clinical trials · 11 currently recruiting

Active & Recent Trials

RECRUITING 2,000 participants

Modifiable Variables in Parkinsonism (MVP)

Bastyr University

NCT02194816

RECRUITING 800 participants

Natural History Study of Synucleinopathies

NYU Langone Health

NCT01799915

RECRUITING 500 participants

North American Prodromal Synucleinopathy Consortium Stage 2

Washington University School of Medicine

NCT05826457

RECRUITING Phase 4 120 participants

Elucidating the Role of Cholinergic Degeneration in Cognitive Fluctuations in Lewy Body Dementia

Virginia Commonwealth University

NCT07284290

RECRUITING 100 participants

Studies of Brain and Body Interaction

Rutgers University

NCT03672266

RECRUITING Phase 4 94 participants

Comparing Antipsychotic Medications in LBD Over Time

The University of Texas Health Science Center at San Antonio

NCT05590637

RECRUITING Phase 2 60 participants

Impact of Nilotinib on Safety, Tolerability, Pharmacokinetics and Biomarkers in Dementia With Lewy Bodies

Georgetown University

NCT04002674

RECRUITING NA 60 participants

Identification of Prodromal Neurodegeneration in Serotonergic-Induced REM Sleep Behavior Disorder

University of Minnesota

NCT06467461

RECRUITING Phase 2 45 participants

K0706 for Patients Diagnosed With Dementia With Lewy Bodies

Georgetown University

NCT03996460

RECRUITING Early Phase 1 40 participants

PET Imaging Evaluation of [11C]SY08

Massachusetts General Hospital

NCT06098612

RECRUITING Phase 1 40 participants

[18F]F-DOPA Imaging in Patients With Autonomic Failure

Daniel Claassen

NCT04246437

ACTIVE NOT RECRUITING Phase 4 2,650 participants

Trial of Parkinson's And Zoledronic Acid

California Pacific Medical Center Research Institute

NCT03924414

ACTIVE NOT RECRUITING 1,000 participants

DIAMOND-Lewy Guidelines for Antipsychotic Use in Older Patients

Ohio State University

NCT06357195

ACTIVE NOT RECRUITING NA 632 participants

Community Outreach for Palliative Engagement -- Parkinson Disease

University of Rochester

NCT05222386

ACTIVE NOT RECRUITING NA 622 participants

PERSEVERE: Peer Mentor Support and Caregiver Education in Lewy Body Dementia

Rush University Medical Center

NCT06389032

ACTIVE NOT RECRUITING 225 participants

Environmental and Reproductive Health Risk for Lewy Body Dementia

University of California, San Diego

NCT06005935

COMPLETED 485 participants

Speech Accessibility Project

University of Illinois at Urbana-Champaign

NCT05889260

COMPLETED 428 participants

Synuclein-One Study

CND Life Sciences

NCT04700722

COMPLETED 219 participants

Family Caregiver Online Survey (Dementia and Swallowing Difficulties)

University of Oregon

NCT06471660

COMPLETED Phase 2 159 participants

RewinD-LB - Clinical Study of Neflamapimod in Patients With Dementia With Lewy Bodies

EIP Pharma

NCT05869669

COMPLETED NA 56 participants

In-Home Care for Patients With PSP and Related Disorders

Rush University Medical Center

NCT03552484

COMPLETED Phase 1 30 participants

A Trial of 18F-AV-133 and 18F-AV-45 Positron Emission Tomography (PET)

Avid Radiopharmaceuticals

NCT01503944

COMPLETED Phase 2 5 participants

Imaging Inflammation in Patients With Parkinson's Disease Dementia or Dementia With Lewy Bodies

Columbia University

NCT02702102

Phase Distribution

PhaseTrial count
Early Phase 1 3
Phase 2 4
Phase 4 3

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Dementia With Lewy Bodies Trial Landscape

ClinicalTrials.gov lists 23 US studies indexed under Dementia With Lewy Bodies, and 11 of those are currently open to recruitment — roughly 48% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Dementia With Lewy Bodies shows 3 late-stage studies (Phase 3 and Phase 4 combined) alongside 7 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Dementia With Lewy Bodies is led by Georgetown University with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 23 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Dementia With Lewy Bodies?

PlainTrial tracks 23 US clinical trials for Dementia With Lewy Bodies, of which 11 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Dementia With Lewy Bodies?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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