Rush University Medical Center

Open enrollment across a mixed-phase pipeline

According to ClinicalTrials.gov-derived indexes, Rush University Medical Center sits in the top decile of US sponsors by registered trial count (#112 of 15,742 sponsors by registered trial count).

320 total trials 53 currently recruiting 206 completed top decile by trial count

Rush University Medical Center: 320 sponsored US clinical trials, 53 recruiting.

Rush University Medical Center sponsors 320 registered US clinical trials on ClinicalTrials.gov, 53 of them currently recruiting, and 206 completed. 42 of these trials are in Phase 3-4 (later-stage) and 41 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Total Knee Arthroplasty, with 3 trials.

Top-decile sponsor footprint

Rush University Medical Center ranks in the top decile of sponsors by registered trial count (#112 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 51/100

206 of 244 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (84.4%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

320 total, page 3 of 7

COMPLETED Phase 4

Duloxetine RCT on Postop TKA Outcomes

NCT05086393

COMPLETED Phase 4

Dexamethasone in Total Knee Arthroplasty

NCT05018091

COMPLETED

Use of Lung Ultrasound in Evaluating Physiological Response to Awake Self Proning

NCT04855162

TERMINATED NA

Genetic Evaluation and Modification of Lifestyles to Improve Female Life Expectancy

NCT05715372

COMPLETED NA

Teen Sleep and Light Study

NCT04921215

COMPLETED NA

Father Inclusive Prenatal Care Study

NCT05652387

COMPLETED NA

The Use of a Digital Application for Reporting Pain and Pain Management in Home Hospice

NCT04869085

COMPLETED NA

The Impact of Circadian Misalignment on Colonic Barrier Homeostasis in Ulcerative Colitis

NCT05180279

COMPLETED NA

Linking Inter-professional Newborn and Contraception Care

NCT04092530

COMPLETED NA

Increasing COVID-19 Testing in Chicago's African American Testing Desserts

NCT05197452

TERMINATED Phase 2

Chemoradiation Followed by Durvalumab in Poor Risk and/or Elderly Patients With Stage III NSCLC

NCT04441138

COMPLETED

A Prospective Clinical Study to Explore Response to Prone Positioning in ARDS Patients

NCT04692779

COMPLETED NA

Different Modalities in Reducing Airborne Particulate Concentrations During AGP for Health Volunteers

NCT04681599

COMPLETED

Innovative Support for Patients With SARS-COV2 Infections (COVID-19) Registry (INSPIRE)

NCT04610515

COMPLETED NA

Addressing Psychological Risk Factors Underlying Smoking Persistence in COPD Patients: The Fresh Start-II Study

NCT04646174

COMPLETED NA

Reducing Disparity in Receipt of Mother's Own Milk in Very Low Birth Weight Infants

NCT04540575

COMPLETED NA

RCT Foley Catheter Study for Elective TJA

NCT05428020

COMPLETED NA

Learning to PERSEVERE: Peer Mentor Support and Caregiver Education in Lewy Body Dementia

NCT04649164

COMPLETED NA

The Fluoroless-CSP Trial Using Electroanatomic Mapping

NCT03903107

COMPLETED NA

Lifestyle Physical Activity and Cognitive Training Interventions

NCT04556305

COMPLETED NA

Psychological Symptoms and Families of COVID-19 Patients

NCT04501445

COMPLETED NA

Prebiotics in the Parkinson's Disease Microbiome

NCT04512599

TERMINATED NA

The Effects of Filter During CPET on WOB and Aerosol Particle Concentrations

NCT04526925

COMPLETED NA

Virtual Enhanced Lifestyle for Metabolic Syndrome (ELM) Proof-of-Concept Study

NCT04637477

COMPLETED Phase 4

A Study of Serum Folate Levels in Patients Treated With Olaparib

NCT04024254

COMPLETED

Investigate the Aerosol Particle Distribution During Aerosol Generating Procedures

NCT04353531

COMPLETED NA

Early PP With HFNC Versus HFNC in COVID-19 Induced Moderate to Severe ARDS

NCT04325906

COMPLETED NA

Early Identification and Prevention of Extubation Failure in Adults Using Integrated Pulmonary Index

NCT04231890

COMPLETED

High Order Spectral Analysis of Local Field Potential Data on a Subgroup of Parkinson's Disease Patients Who Are Carriers of Mutations in the Glucocerebrosidase (GBA) Gene Undergoing DBS Electrode Placement

NCT04268030

COMPLETED Phase 4

Evaluating Vitamin D3 Supplement on Post-Op Outcomes

NCT04177758

COMPLETED NA

Telerehabilitation for Parkinson's Disease

NCT04600011

COMPLETED

Donor-Derived Cell-Free DNA for Surveillance in Simultaneous Pancreas and Kidney Transplant Recipients

NCT04130685

TERMINATED Phase 4

Compare the Diuretic Effect With Furosemide vs Furosemide and Albumin Combined in Cirrhotic Patients

NCT04216784

COMPLETED NA

Physical Activity to Improve Physical Function in a Community-Based Health Ministry

NCT04203030

COMPLETED NA

Evaluation of the CleanSweep™ Closed Suction System on Length of Mechanical Ventilation and Ventilator-Associated Events

NCT03868735

TERMINATED Phase 2

Effect of Topical CBD Cream for Degenerative Hallux Disorders

NCT04103814

COMPLETED NA

Examining Changes in Microbiota Over the Course of PTSD Treatment

NCT04109196

TERMINATED NA

Nickel Sensitivity

NCT04058743

COMPLETED NA

Addressing Psychological Risk Factors Underlying Smoking Persistence in COPD Patients: The Fresh Start Study

NCT04043728

TERMINATED NA

Treadmill Training in Fragile X-associated Tremor/Ataxia Syndrome

NCT04428567

COMPLETED NA

Enhanced Lifestyles for Metabolic Syndrome

NCT04036006

COMPLETED NA

Rounding Summaries for Families of Critically Ill Patients

NCT03969810

COMPLETED NA

Dilute Betadine Soak and Scrub for Foot and Ankle Surgery

NCT03926208

COMPLETED NA

ISOVUE Comparative Trial

NCT07363759

COMPLETED NA

Dementia Caregiver Chronic Grief Management: A Live Online Video Intervention

NCT03593070

COMPLETED NA

Using Neuroplasticity-Based Computerized Training to Improve Emotion Regulation in Bipolar Disorder (BRAINS)

NCT05683431

COMPLETED NA

Kick Out Parkinson's Disease 2

NCT03882879

COMPLETED NA

Help Everyone Assess Risk Today: LEnten Nutrition Study (HEART-LENS)

NCT05057650

COMPLETED NA

Feasibility Trial of Narrative Exposure Therapy (NET) for Posttraumatic Stress Disorder (PTSD) During Pregnancy

NCT04525469

COMPLETED NA

Home Exercise vs PT for Reverse Total Shoulder Arthroplasty

NCT03719859

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Phase Distribution

PhaseTrial count
Phase 1 16
Phase 2 25
Phase 3 6
Phase 4 36

What is open in the Rush University Medical Center pipeline

53 recruiting of 320 indexed (17% open); 206 completed (64%).

Phase mix: 42 late (III/IV) vs 41 early (I/II) (balanced across stages).

Top condition: Total Knee Arthroplasty (3 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Rush University Medical Center: open-pipeline peers nationwide

Peers matched on 320 registered trials and 17% open enrollment, not the therapeutic-area sidebar.

Rush University Medical Center sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,5002,0002,500 0%5%10%15%20% Total trials Recruiting share Rush University Medical CenterJonsson Comprehensive Cancer CenterUniversity of ArkansasAllerganGenentechOHSU Knight Cancer InstituteMassachusetts General HospitalAdageneAgendia
Rush University Medical Center sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Rush University Medical Center sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 320 trials (± recruiting share)

Sponsors near 17% open enrollment (± trial volume)

What to do with this Rush University Medical Center page

320 registered trials is a research-attention snapshot, not an endorsement of Rush University Medical Center or any single study.

  • 53 of Rush University Medical Center's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Total Knee Arthroplasty is the condition Rush University Medical Center studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Total Knee Arthroplasty trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Rush University Medical Center pipeline card: 320 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.