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NCT02749721 · ClinicalTrials.gov registry record · Phase 4
The Relationship Among Changes in Brain Network Activation in Adult Outpatients With Major Depressive Disorder
A Phase 4 study, sponsored by Rush University Medical Center.
- Completed
- Registry status
- Phase 4
- Development phase
- 31
- Enrollment target
NCT02749721: Completed Phase 4 study, sponsored by Rush University Medical Center.
NCT02749721 is a Phase 4 study that has completed, run by Rush University Medical Center. The registered enrollment target is 31 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (94% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02749721, a Phase 4 study, has completed, sponsored by Rush University Medical Center.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 31 participants
- Enrollment target
Study Summary
The purpose of this study is to explore patterns of Brain Network Activation (BNA) changes from baseline to endpoint on 1) efficacy of core symptoms of Major Depressive Disorder (MDD) and 2) improvement of cognitive dysfunction with acute treatment with flexible dose vortioxetine in adult outpatients with MDD and subjective complaints of cognitive dysfunction.
Primary Outcome
The MADRS is a 10-item rating scale designed to assess the severity of symptoms of depression. Range is 0-60. Higher score means more severe.
Interventions
- DRUG vortioxetine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 31 participants |
| Start Date | 2016-12 |
| Est. Completion | 2019-01-31 |
| Phase | Phase 4 |
What the finished NCT02749721 record still lists
NCT02749721 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 31 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (94% lower).
The record links to 0 conditions, and to 1 intervention - of which vortioxetine is the first listed.
NCT02749721 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02749721 about?
NCT02749721 is a clinical study titled "The Relationship Among Changes in Brain Network Activation in Adult Outpatients With Major Depressive Disorder". The purpose of this study is to explore patterns of Brain Network Activation (BNA) changes from baseline to endpoint on 1) efficacy of core symptoms of Major Depressive Disorder (MDD) and 2) improvement of cognitive dysfunction with acute treatment with flexible dose vortioxetine in adult outpatient...
What is the current status of trial NCT02749721?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 31 participants. The study started on 2016-12. Estimated completion is 2019-01-31.
What interventions are being tested in trial NCT02749721?
The interventions under investigation include: vortioxetine (DRUG).
Who is sponsoring clinical trial NCT02749721?
This trial is sponsored by Rush University Medical Center, which has 320 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02749721's enrollment target sits among peer trials
31 1544th of 2000 higher than 449 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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