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NCT03347604 · ClinicalTrials.gov registry record
Effect of Body Position on Spirometry in Abdominal Obesity.
A clinical trial, sponsored by Rush University Medical Center.
- Completed
- Registry status
- 30
- Enrollment target
NCT03347604 is a clinical trial that has completed, run by Rush University Medical Center. The registered enrollment target is 30 participants.
The verdict
NCT03347604 has completed, sponsored by Rush University Medical Center.
- COMPLETED
- Registry status
- 30 participants
- Enrollment target
Study Summary
Objective: Study the effect of body position on spirometry in obese patients as defined by waist to hip ratio (WHR) of greater than 0.85 in women, and 0.9 in men Background: Spirometry is routinely ordered to work up dyspnea in obesity. The most common abnormality is a restrictive disease pattern. The underlying mechanisms of this pattern are not completely understood. One plausible explanation is diaphragmatic weakness or skeletal muscle weakness. The change in forced vital capacity (FVC) from sitting to supine is a very sensitive and specific test for detecting diaphragmatic weakness. The effect of body position on spirometry in obesity has not been extensively studied, and there are no studies that look at this when obesity is measured by waist to hip ratio. Effect of body position has been studied in normal patients, and it is expected the FVC can decrease as much as 10% when changing from sitting to supine. The investigators do not know what would be considered 'the normal' amount for FVC to decrease by in the obese population, and thus would like to test patients with increased WHR both in sitting and supine position. The investigators also want to do muscle strength test by measuring the maximal inspiratory and expiratory pressures (MIPs and MEPs). Anticipated results: the investigators anticipate that our study population will replicate the restrictive disease pattern usually seen in obesity. The investigators also anticipate for the FVC to decrease when in the supine position compared to sitting. The amount by which it decreases will likely fall between 10 -25%. The investigators anticipate to not find any abnormalities in MIPs and MEPs in obesity.
Interventions
- DIAGNOSTIC_TEST Supine spirometry, MIPs and MEPs
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2017-10-06 |
| Est. Completion | 2018-12-30 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03347604
The ClinicalTrials.gov registry entry for NCT03347604 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Rush University Medical Center, which has 320 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Supine spirometry, MIPs and MEPs is the first listed.
NCT03347604 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT03347604 about?
NCT03347604 is a clinical study titled "Effect of Body Position on Spirometry in Abdominal Obesity.". Objective: Study the effect of body position on spirometry in obese patients as defined by waist to hip ratio (WHR) of greater than 0.85 in women, and 0.9 in men Background: Spirometry is routinely ordered to work up dyspnea in obesity. The most common abnormality is a restrictive disease pattern. ...
What is the current status of trial NCT03347604?
This trial is currently completed. The enrollment target is 30 participants. The study started on 2017-10-06. Estimated completion is 2018-12-30.
What interventions are being tested in trial NCT03347604?
The interventions under investigation include: Supine spirometry, MIPs and MEPs (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT03347604?
This trial is sponsored by Rush University Medical Center, which has 320 total clinical trials registered on ClinicalTrials.gov.
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