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NCT04646174 · ClinicalTrials.gov registry record · NA
Addressing Psychological Risk Factors Underlying Smoking Persistence in COPD Patients: The Fresh Start-II Study
A NA study, sponsored by Rush University Medical Center.
- Completed
- Registry status
- NA
- Development phase
- 66
- Enrollment target
NCT04646174: Completed NA study, sponsored by Rush University Medical Center.
NCT04646174 is a NA study that has completed, run by Rush University Medical Center. The registered enrollment target is 66 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04646174, a NA study, has completed, sponsored by Rush University Medical Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 66 participants
- Enrollment target
Study Summary
Chronic Obstructive Pulmonary Disease (COPD) is caused primarily by smoking and smoking cessation is the first-line treatment for slowing disease progression. Despite this, nearly 50% of COPD patients continue to smoke following diagnosis. Smokers with COPD report high rates of co-occurring conditions - nicotine dependence, depression, and anxiety - which serve as barriers to quitting. The current study will pilot test a behavioral intervention designed to target the common psychological factors underlying these co-occurring conditions and foster smoking cessation among COPD patients.
Primary Outcome
Number of days abstinent for 2 weeks post-quit, as verified by CO \< 5 ppm
Interventions
- BEHAVIORAL Unified Protocol adapted for smoking cessation
- BEHAVIORAL American Lung Association self-management strategies for smoking cessation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 66 participants |
| Start Date | 2020-12-14 |
| Est. Completion | 2022-12-31 |
| Phase | NA |
What the finished NCT04646174 record still lists
NCT04646174 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 66 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower).
The record links to 0 conditions, and to 2 interventions - of which Unified Protocol adapted for smoking cessation is the first listed.
NCT04646174 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04646174 about?
NCT04646174 is a clinical study titled "Addressing Psychological Risk Factors Underlying Smoking Persistence in COPD Patients: The Fresh Start-II Study". Chronic Obstructive Pulmonary Disease (COPD) is caused primarily by smoking and smoking cessation is the first-line treatment for slowing disease progression. Despite this, nearly 50% of COPD patients continue to smoke following diagnosis. Smokers with COPD report high rates of co-occurring conditio...
What is the current status of trial NCT04646174?
This trial is currently completed. It is a NA study. The enrollment target is 66 participants. The study started on 2020-12-14. Estimated completion is 2022-12-31.
What interventions are being tested in trial NCT04646174?
The interventions under investigation include: Unified Protocol adapted for smoking cessation (BEHAVIORAL), American Lung Association self-management strategies for smoking cessation (BEHAVIORAL).
Who is sponsoring clinical trial NCT04646174?
This trial is sponsored by Rush University Medical Center, which has 320 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04646174's enrollment target sits among peer trials
66 1139th of 2000 higher than 857 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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