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NCT05086393 · ClinicalTrials.gov registry record · Phase 4

Duloxetine RCT on Postop TKA Outcomes

A Phase 4 study, sponsored by Rush University Medical Center.

Completed
Registry status
Phase 4
Development phase
241
Enrollment target

NCT05086393 is a Phase 4 study that has completed, run by Rush University Medical Center. The registered enrollment target is 241 participants.

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The verdict

NCT05086393, a Phase 4 study, has completed, sponsored by Rush University Medical Center.

COMPLETED
Registry status
Phase 4
Development phase
241 participants
Enrollment target

Study Summary

The aim of this study is to determine if duloxetine is associated with differences in post-operative pain, patient-reported outcome measures, and opioid consumption in patients undergoing primary total knee arthroplasty compared to patients who do not receive the medication. If so, duloxetine has the potential to become widely incorporated into the multi-modal analgesic regimen given to patients following knee replacements.

Interventions

  • DRUG Duloxetine
  • DRUG Placebos

Trial Details

FieldValue
Enrollment Target 241 participants
Start Date 2021-11-01
Est. Completion 2025-07-23
Phase Phase 4

Sponsor

Rush University Medical Center

320 total trials

What the Registry Record Tells You About NCT05086393

The ClinicalTrials.gov registry entry for NCT05086393 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 241 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Rush University Medical Center, which has 320 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Duloxetine is the first listed.

NCT05086393 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT05086393 about?

NCT05086393 is a clinical study titled "Duloxetine RCT on Postop TKA Outcomes". The aim of this study is to determine if duloxetine is associated with differences in post-operative pain, patient-reported outcome measures, and opioid consumption in patients undergoing primary total knee arthroplasty compared to patients who do not receive the medication. If so, duloxetine has th...

What is the current status of trial NCT05086393?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 241 participants. The study started on 2021-11-01. Estimated completion is 2025-07-23.

What interventions are being tested in trial NCT05086393?

The interventions under investigation include: Duloxetine (DRUG), Placebos (DRUG).

Who is sponsoring clinical trial NCT05086393?

This trial is sponsored by Rush University Medical Center, which has 320 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.