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NCT04325906 · ClinicalTrials.gov registry record · NA
Early PP With HFNC Versus HFNC in COVID-19 Induced Moderate to Severe ARDS
A NA study of Acute Respiratory Distress Syndrome and Corona Virus Infection, sponsored by Rush University Medical Center.
- Completed
- Registry status
- NA
- Development phase
- 224
- Enrollment target
- 1
- Study location
NCT04325906: Completed NA study of Acute Respiratory Distress Syndrome and Corona Virus Infection, sponsored by Rush University Medical Center.
NCT04325906 is a NA study of Acute Respiratory Distress Syndrome and Corona Virus Infection that has completed, run by Rush University Medical Center. The registered enrollment target is 224 participants, below the 360-participant average among 31 other Acute Respiratory Distress Syndrome trials with a reported enrollment target (38% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04325906, a NA study of Acute Respiratory Distress Syndrome and Corona Virus Infection, has completed, sponsored by Rush University Medical Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 224 participants
- Enrollment target
- 1
- Study location
Study Summary
Coronavirus disease 2019 (COVID-19) is an emerging infectious disease that was first reported in Wuhan, China, and had subsequently spread worldwide. Twenty-nine percent of COVID-19 patients may develop ARDS. Based on the potential beneficial mechanisms of HFNC and PP, whether early use of prone positioning combined with HFNC can avoid the need for intubation in COVID-19 induced moderate to severe ARDS patients needs to be further investigated.
Primary Outcome
the treatment failure rate of HFNC/HFNC+PP support within 28 days of study enrollment
Conditions Studied
Interventions
- DEVICE high flow nasal cannula (HFNC)
- PROCEDURE Prone positioning (PP)
Study Locations (1)
Illinois
- Rush University Medical Center - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 224 participants |
| Start Date | 2020-04-02 |
| Est. Completion | 2021-02-21 |
| Phase | NA |
What the finished NCT04325906 record still lists
NCT04325906 is an interventional study that assigns participants to a tested intervention. The registered 224 participants enrollment target is mid-sized for trials with a published cap, below the 360-participant average among 31 other Acute Respiratory Distress Syndrome trials with a reported enrollment target (38% lower).
The record links to 4 conditions, with Acute Respiratory Distress Syndrome appearing as the primary indexed condition, and to 2 interventions - of which high flow nasal cannula (HFNC) is the first listed.
NCT04325906 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT04325906 about?
NCT04325906 is a clinical study titled "Early PP With HFNC Versus HFNC in COVID-19 Induced Moderate to Severe ARDS". Coronavirus disease 2019 (COVID-19) is an emerging infectious disease that was first reported in Wuhan, China, and had subsequently spread worldwide. Twenty-nine percent of COVID-19 patients may develop ARDS. Based on the potential beneficial mechanisms of HFNC and PP, whether early use of prone pos...
What is the current status of trial NCT04325906?
This trial is currently completed. It is a NA study. The enrollment target is 224 participants. The study started on 2020-04-02. Estimated completion is 2021-02-21.
What conditions does trial NCT04325906 study?
This clinical trial studies the following conditions: Acute Respiratory Distress Syndrome, Corona Virus Infection, Prone Positioning, High Flow Nasal Cannula.
What interventions are being tested in trial NCT04325906?
The interventions under investigation include: high flow nasal cannula (HFNC) (DEVICE), Prone positioning (PP) (PROCEDURE).
Who is sponsoring clinical trial NCT04325906?
This trial is sponsored by Rush University Medical Center, which has 320 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04325906 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT04325906's enrollment target sits among peer trials
224 9th of 31 higher than 23 of 31 other Acute Respiratory Distress Syndrome trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Acute Respiratory Distress Syndrome trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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