Roswell Park Cancer Institute

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Roswell Park Cancer Institute sits in the top decile of US sponsors by registered trial count (#98 of 15,742 sponsors by registered trial count).

365 total trials 57 currently recruiting 200 completed early-phase tilt top decile by trial count

Roswell Park Cancer Institute: 365 sponsored US clinical trials, 57 recruiting.

Roswell Park Cancer Institute sponsors 365 registered US clinical trials on ClinicalTrials.gov, 57 of them currently recruiting, and 200 completed. 7 of these trials are in Phase 3-4 (later-stage) and 238 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Leukemia, with 9 trials.

Top-decile sponsor footprint

Roswell Park Cancer Institute ranks in the top decile of sponsors by registered trial count (#98 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 18/100

200 of 279 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (71.7%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

365 total, page 4 of 8

TERMINATED NA

Art in Improving Outcomes in Participants Undergo Surgery

NCT03688945

COMPLETED Phase 2

Olaparib, Durvalumab, and Tremelimumab in Treating Patients With Recurrent or Refractory Ovarian, Fallopian Tube or Primary Peritoneal Cancer With BRCA1 or BRCA2 Mutation

NCT02953457

COMPLETED Phase 1

Nimotuzumab and Nivolumab in Treating Patients With Advanced Non-small Cell Lung Cancer

NCT02947386

COMPLETED Phase 2

Physical Activity Monitored by Fitbit Charge 2 in Improving Quality of Life in Participants With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

NCT03685695

COMPLETED NA

Talking Pictures Social Media Intervention in Reducing Depressive Symptoms and Improving Spiritual Well-Being and Quality of Life in Adolescent and Young Adult Cancer Patients

NCT03679585

COMPLETED Phase 2

Botulinum Toxin Type A in Preventing Complications After Surgery in Patients With Esophageal Cancer

NCT02965976

COMPLETED NA

Intravital Microscopy in Identifying Tumor Vessels in Patients With Stage IB-IIIC Melanoma Undergoing Sentinel Lymph Node Biopsy

NCT02857374

COMPLETED Phase 2

Pembrolizumab, Bevacizumab, and Cyclophosphamide in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

NCT02853318

COMPLETED Phase 1

Cetuximab and Pembrolizumab in Treating Patients With Colorectal Cancer That is Metastatic or Cannot Be Removed by Surgery

NCT02713373

COMPLETED NA

Informational Intervention in Increasing Lactation Practices by African American Women

NCT03680235

COMPLETED NA

Omission of Intact Parathyroid Hormone Testing During Surgery in Treating Patients With Primary Hyperparathyroidism

NCT03011736

COMPLETED NA

Nicotine Delivery From Novel Non-Tobacco Electronic System in Smokers

NCT02575885

TERMINATED Phase 2

Nintedanib Compared With Placebo in Treating Against Radiation-Induced Pneumonitis in Patients With Non-small Cell Lung Cancer That Cannot Be Removed by Surgery and Are Undergoing Chemoradiation Therapy

NCT02452463

COMPLETED Phase 2

Nintedanib in Treating Patients With Locally Advanced or Metastatic Neuroendocrine Tumors

NCT02399215

COMPLETED Phase 1

Nintedanib and Capecitabine in Treating Patients With Refractory Metastatic Colorectal Cancer

NCT02393755

TERMINATED Phase 1

Ribociclib and Gemcitabine Hydrochloride in Treating Patients With Advanced Solid Tumors or Lymphoma

NCT02414724

COMPLETED Phase 1

Gabapentin, Methadone Hydrochloride, and Oxycodone Hydrochloride in Improving Quality of Life in Patients With Stage II-IV Head and Neck Cancer During Chemoradiation

NCT02531906

COMPLETED Phase 1

Ceritinib and Combination Chemotherapy in Treating Patients With Advanced Solid Tumors or Locally Advanced or Metastatic Pancreatic Cancer

NCT02227940

COMPLETED Phase 2

Sipuleucel-T With or Without Tasquinimod in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer

NCT02159950

COMPLETED NA

Acupuncture-Like Transcutaneous Electrical Nerve Stimulation in Treating Radiation-Induced Xerostomia in Patients With Head and Neck Cancer

NCT02474095

TERMINATED NA

Vaccine Therapy Before Surgery in Treating Patients With Localized Kidney Cancer

NCT02170389

COMPLETED Phase 1

DEC-205/NY-ESO-1 Fusion Protein CDX-1401, Poly ICLC, and IDO1 Inhibitor INCB024360 in Treating Patients With Ovarian, Fallopian Tube, or Primary Peritoneal Cancer in Remission

NCT02166905

TERMINATED Phase 2

Omacetaxine Mepesuccinate, Cytarabine, and Decitabine in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia

NCT02029417

TERMINATED Phase 2

Cholecalciferol Supplementation in Strengthening Inspiratory Muscles in Cholecalciferol-Deficient Patients With Chronic Obstructive Pulmonary Disease

NCT02877641

TERMINATED Phase 2

Interstitial Photodynamic Therapy in Treating Patients With Recurrent Head and Neck Cancer

NCT02068157

COMPLETED Phase 1

Photodynamic Therapy During Surgery in Treating Patients With Non-small Cell Lung Cancer That Can Be Removed by Surgery

NCT01854684

COMPLETED Phase 2

Nintedanib in Treating Patients With Advanced Non-Small Cell Lung Cancer Who Have Failed Up to Two Previous Chemotherapy Regimens

NCT01948141

COMPLETED NA

Sorafenib Tosylate in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery

NCT02072486

COMPLETED NA

Body Warming in Improving Blood Flow and Oxygen Delivery to Tumors in Patients With Cancer

NCT01896778

COMPLETED NA

Intravital Microscopy for Identifying Tumor Vessels in Patients With Stage IA-IV Melanoma That is Being Removed by Surgery

NCT01886235

COMPLETED Phase 2

Pegylated Irinotecan NKTR 102 in Treating Patients With Relapsed Small Cell Lung Cancer

NCT01876446

COMPLETED Phase 1

DEC-205/NY-ESO-1 Fusion Protein CDX-1401and Decitabine in Treating Patients With Myelodysplastic Syndrome or Acute Myeloid Leukemia

NCT01834248

COMPLETED NA

Stereotactic Body Radiation Therapy in Treating Patients With Metastatic Kidney Cancer Undergoing Surgery

NCT01892930

COMPLETED Phase 1

Tivozanib in Treating Patients With Liver Cancer That Is Metastatic or Cannot Be Removed by Surgery

NCT01835223

COMPLETED NA

Radiation Therapy in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer Receiving Sipuleucel-T

NCT01833208

COMPLETED Early Phase 1

Broccoli Sprout Extract in Treating Patients With Breast Cancer

NCT01753908

TERMINATED Phase 2

Radiation Therapy in Treating Post-Menopausal Women With Early Stage Breast Cancer Undergoing Surgery

NCT01754519

TERMINATED Phase 1

Vaccine Therapy in Treating Patients With Advanced Stage III-IV Melanoma

NCT01744171

COMPLETED Early Phase 1

Stereotactic Body Radiation Therapy After Surgery in Treating Patients With Stage III-IV Non-small Cell Lung Cancer

NCT01781741

COMPLETED NA

Biomarkers in Post-Menopausal Women Receiving Flaxseed

NCT01698294

COMPLETED NA

Varenicline or Nicotine Patch in Promoting Smoking Cessation Among Current Smokers

NCT01771627

TERMINATED Phase 1

Chemokine-Modulatory Regimen for Recurrent Resectable Colorectal Cancer

NCT01545141

COMPLETED Phase 1

Vaccine Therapy and Sargramostim in Treating Patients With Malignant Glioma

NCT01250470

COMPLETED Phase 1

Sirolimus and Vaccine Therapy in Treating Patients With Stage II-IV Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cavity Cancer

NCT01536054

COMPLETED Phase 1

PI3K Inhibitor BKM120 and Docetaxel in Treating Patients With Advanced Solid Tumor That is Locally Advanced, Cannot Be Removed By Surgery, or Metastatic

NCT01540253

TERMINATED Phase 1

Eltrombopag Olamine in Treating Patients With Relapsed/Refractory Acute Myeloid Leukemia

NCT01550185

TERMINATED Phase 1

Gemcitabine Hydrochloride and Smac Mimetic TL32711 in Treating Patients With Advanced Solid Tumors

NCT01573780

TERMINATED Phase 2

Ofatumumab and Bortezomib in Treating Patients With Previously Untreated Waldenstrom Macroglobulinemia

NCT01536067

COMPLETED Phase 1

Dovitinib Lactate, Gemcitabine Hydrochloride, and Capecitabine in Treating Patients With Advanced or Metastatic Solid Tumors, Pancreatic Cancer and Biliary Cancers

NCT01497392

COMPLETED Phase 1

Vaccine Therapy With or Without Sirolimus in Treating Patients With NY-ESO-1 Expressing Solid Tumors

NCT01522820

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What is open in the Roswell Park Cancer Institute pipeline

57 recruiting of 365 indexed (16% open); 200 completed (55%).

Phase mix: 7 late (III/IV) vs 238 early (I/II) (early-phase heavy).

Top condition: Leukemia (9 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Roswell Park Cancer Institute: open-pipeline peers nationwide

Peers matched on 365 registered trials and 16% open enrollment, not the therapeutic-area sidebar.

Roswell Park Cancer Institute sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0200400600800 0%5%10%15%20%25% Total trials Recruiting share Roswell Park Cancer InstituteUNC Lineberger Comprehensive Cancer CenterNew York State Psychiatric InstituteUniversity of California, IrvineNorthwell HealthCambridge Health AllianceLouisiana State University Health Sciences Center in New OrleansUniversity of Southern CaliforniaIncyte Corporation
Roswell Park Cancer Institute sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Roswell Park Cancer Institute sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 365 trials (± recruiting share)

Sponsors near 16% open enrollment (± trial volume)

What to do with this Roswell Park Cancer Institute page

365 registered trials is a research-attention snapshot, not an endorsement of Roswell Park Cancer Institute or any single study.

  • 57 of Roswell Park Cancer Institute's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Leukemia is the condition Roswell Park Cancer Institute studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Leukemia trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Roswell Park Cancer Institute pipeline card: 365 registered trials from official public datasets.Report a data error.