Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT03925532 · ClinicalTrials.gov registry record · Phase 2

Denosumab in Treating Patients With Bone Loss Due to Donor Stem Cell Transplant

A Phase 2 study, sponsored by Roswell Park Cancer Institute.

Completed
Registry status
Phase 2
Development phase
30
Enrollment target

NCT03925532 is a Phase 2 study that has completed, run by Roswell Park Cancer Institute. The registered enrollment target is 30 participants.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT03925532, a Phase 2 study, has completed, sponsored by Roswell Park Cancer Institute.

COMPLETED
Registry status
Phase 2
Development phase
30 participants
Enrollment target

Study Summary

This Phase II trial studies the side effects of denosumab and to see how well it works in treating patients with bone loss who have received a donor stem cell transplant. Patients receiving a donor stem cell transplant may experience accelerated bone loss and an increase risk of bone fractures, leading to a decrease in satisfaction and quality of life. A type of immunotherapy drug called denosumab binds to a protein called RANKL, which may help keep bone from breaking down.

Interventions

  • BIOLOGICAL Denosumab

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2019-12-19
Est. Completion 2022-11-16
Phase Phase 2

Sponsor

Roswell Park Cancer Institute

365 total trials

What the Registry Record Tells You About NCT03925532

The ClinicalTrials.gov registry entry for NCT03925532 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Roswell Park Cancer Institute, which has 365 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Denosumab is the first listed.

NCT03925532 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03925532 about?

NCT03925532 is a clinical study titled "Denosumab in Treating Patients With Bone Loss Due to Donor Stem Cell Transplant". This Phase II trial studies the side effects of denosumab and to see how well it works in treating patients with bone loss who have received a donor stem cell transplant. Patients receiving a donor stem cell transplant may experience accelerated bone loss and an increase risk of bone fractures, lead...

What is the current status of trial NCT03925532?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 30 participants. The study started on 2019-12-19. Estimated completion is 2022-11-16.

What interventions are being tested in trial NCT03925532?

The interventions under investigation include: Denosumab (BIOLOGICAL).

Who is sponsoring clinical trial NCT03925532?

This trial is sponsored by Roswell Park Cancer Institute, which has 365 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.