Nationwide Children's Hospital
Nationwide Children's Hospital sponsors 188 registered US clinical trials on ClinicalTrials.gov, 29 of them currently recruiting, and 122 completed. 13 of these trials are in Phase 3-4 (later-stage) and 50 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is High Grade Glioma, with 8 trials.
Trial Pipeline
188 total, page 1 of 4
Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion
NCT06333899
ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas
NCT06838676
Observation Study in Patients Age 0-5 Years With LAMA2-related Congenital Muscular Dystrophy
NCT06503367
Phase 1 Study of Locoregional Injections of Ex Vivo Expanded Natural Killer Cells
NCT04254419
Pediatric Cochlear Implant Remote Programming and Assessment
NCT07035873
Preparing for Life and Academics for Young Childhood Cancer Survivors
NCT06769334
Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant
NCT05843253
Targeted Pediatric High-Grade Glioma Therapy
NCT05839379
PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma
NCT05096481
Applying Directly Observed Therapy to Hydroxyurea to Realize Effectiveness
NCT06264700
GERD Infant Feeding Therapeutics Trial (GIFT Trial)
NCT06114836
Improving Status Epilepticus Treatment Times
NCT06194747
αβT Cell/CD19+ B Cell Depletion for Alternative Donor Allogeneic Hematopoietic Cell Transplantation (HSCT)
NCT06082947
DOSC and Association With Neighborhood Opportunity: Phase II
NCT05939570
MEKTOVI® for the Treatment of Pediatric Adamantinomatous Craniopharyngioma
NCT05286788
Percutaneous Intervention Versus Observational Trial of Arterial Ductus in Low Weight Infants
NCT05547165
ACTEMRA® for the Treatment of Pediatric Adamantinomatous Craniopharyngioma
NCT05233397
Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors
NCT05278208
A Multi-Institution Study of TGFβ Imprinted, Ex Vivo Expanded Universal Donor NK Cell Infusions as Adoptive Immunotherapy in Combination With Gemcitabine and Docetaxel in Patients With Relapsed or Refractory Pediatric Bone and Soft Tissue
NCT05634369
NK Cells Infusions With Irinotecan, Temozolomide, and Dinutuximab
NCT04211675
A Study of Cabozantinib as a Maintenance Agent to Prevent Progression or Recurrence in High-Risk Pediatric Solid Tumors
NCT05135975
Targeted Reversal of Inflammation in Pediatric Sepsis-induced MODS
NCT05267821
Safety and Efficacy of Expanded, Universal Donor Natural Killer Cells for Relapsed/Refractory AML
NCT05503134
Pilot Study of Haploidentical Donor Adenovirus Specific T-lymphocytes to Treat Refractory Adenovirus Infections
NCT04722029
A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion
NCT04655404
Two-Year Study of the Safety and Efficacy of the Second-Generation Tissue Engineered Vascular Grafts
NCT04467671
Early Predictors of Necrotizing Enterocolitis in Neonates
NCT03210831
Radiotracer-Based Perfusion Imaging of Patients With Peripheral Arterial Disease
NCT03622359
Genetics of Congenital Heart Disease
NCT01192048
Metabolomic Profiling of Racial Disparity
NCT06266429
Regional Anesthesia EMG Study
NCT06287151
VR-PAT for Pain and Anxiety Management During Pediatric Dermatologic Laser Procedures
NCT05645224
Evaluating an Intervention to Prevent Overdoses in Rural and Urban Counties
NCT05463341
Natural History Study of Patients With VCP-related Disease
NCT04823143
Early Prediction of Spontaneous Patent Ductus Arteriosus (PDA) Closure and PDA-Associated Outcomes
NCT03782610
GM-CSF for Reversal of immunopAralysis in pediatriC sEpsis-induced MODS Study
NCT03769844
A Phase 1b Study of PTC596 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma and High Grade Glioma
NCT03605550
Haploidentical Hematopoietic Cell Transplantation for Children With Hematologic Malignancies and Myelodysplasia
NCT03431090
Characterization of Clinical Skeletal and Cardiac Impairment in Carriers of DMD and BMD
NCT02972580
MIBG Therapy for Patients With MIBG Avid Tumors
NCT02378428
Phase I/IIa Trial of scAAV1.tMCK.NTF3 for Treatment of CMT1A
NCT03520751
Comparison of Neurocognitive Outcome in Two Standard Regimen for Treatment of Low-risk Medulloblastoma
NCT07291102
VR-PAT and fNIRS to Identify CNS Biomarkers of Pain
NCT06303687
Phase I/II Clinical Trial of Universal Donor CD33 CAR Natural Killer Cells for AML
NCT07026942
Safety and Feasibility of CD19 CAR T Cells Using CliniMACS Prodigy for Relapsed/Refractory CD19 Positive ALL and NHL
NCT05779930
Spanish BMT4me Usability & Acceptability
NCT06361173
Preoperative Survey to Evaluate Patient Allergy
NCT05670756
A Pilot Study of Collaborative Assessment and Management of Suicidality With Suicidal Children ("CAMS-4Kids")
NCT04119648
Baclofen for Children With Rumination Syndrome
NCT05975684
Psychologically Informed Education Intervention for Adolescents With Atraumatic Lower-Extremity Injuries
NCT05701618
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 21 |
| Phase 2 | 29 |
| Phase 3 | 8 |
| Phase 4 | 5 |
Therapeutic Areas
What the Pipeline for Nationwide Children's Hospital Shows
According to the ClinicalTrials.gov registry, Nationwide Children's Hospital is linked to 188 US clinical trials across every stage of research activity. Of those, 29 studies are currently recruiting, about 15% of the sponsor's indexed portfolio, and 122 are already marked complete, representing roughly 65% of the total.
The phase mix for Nationwide Children's Hospital reports 13 late-stage studies (Phase 3 and Phase 4 combined) and 50 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for Nationwide Children's Hospital is High Grade Glioma with 8 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.