Nationwide Children's Hospital

188 total trials 29 currently recruiting 122 completed

Nationwide Children's Hospital sponsors 188 registered US clinical trials on ClinicalTrials.gov, 29 of them currently recruiting, and 122 completed. 13 of these trials are in Phase 3-4 (later-stage) and 50 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is High Grade Glioma, with 8 trials.

Trial Pipeline

188 total, page 1 of 4

RECRUITING Early Phase 1

Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion

NCT06333899

RECRUITING Phase 2

ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas

NCT06838676

RECRUITING

Observation Study in Patients Age 0-5 Years With LAMA2-related Congenital Muscular Dystrophy

NCT06503367

RECRUITING Phase 1

Phase 1 Study of Locoregional Injections of Ex Vivo Expanded Natural Killer Cells

NCT04254419

RECRUITING NA

Pediatric Cochlear Implant Remote Programming and Assessment

NCT07035873

RECRUITING NA

Preparing for Life and Academics for Young Childhood Cancer Survivors

NCT06769334

RECRUITING Phase 2

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

NCT05843253

RECRUITING

Targeted Pediatric High-Grade Glioma Therapy

NCT05839379

RECRUITING Phase 2

PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma

NCT05096481

RECRUITING NA

Applying Directly Observed Therapy to Hydroxyurea to Realize Effectiveness

NCT06264700

RECRUITING NA

GERD Infant Feeding Therapeutics Trial (GIFT Trial)

NCT06114836

RECRUITING NA

Improving Status Epilepticus Treatment Times

NCT06194747

RECRUITING NA

αβT Cell/CD19+ B Cell Depletion for Alternative Donor Allogeneic Hematopoietic Cell Transplantation (HSCT)

NCT06082947

RECRUITING

DOSC and Association With Neighborhood Opportunity: Phase II

NCT05939570

RECRUITING Phase 2

MEKTOVI® for the Treatment of Pediatric Adamantinomatous Craniopharyngioma

NCT05286788

RECRUITING NA

Percutaneous Intervention Versus Observational Trial of Arterial Ductus in Low Weight Infants

NCT05547165

RECRUITING Phase 2

ACTEMRA® for the Treatment of Pediatric Adamantinomatous Craniopharyngioma

NCT05233397

RECRUITING Phase 1

Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors

NCT05278208

RECRUITING Phase 1

A Multi-Institution Study of TGFβ Imprinted, Ex Vivo Expanded Universal Donor NK Cell Infusions as Adoptive Immunotherapy in Combination With Gemcitabine and Docetaxel in Patients With Relapsed or Refractory Pediatric Bone and Soft Tissue

NCT05634369

RECRUITING Phase 1

NK Cells Infusions With Irinotecan, Temozolomide, and Dinutuximab

NCT04211675

RECRUITING Phase 2

A Study of Cabozantinib as a Maintenance Agent to Prevent Progression or Recurrence in High-Risk Pediatric Solid Tumors

NCT05135975

RECRUITING Phase 2

Targeted Reversal of Inflammation in Pediatric Sepsis-induced MODS

NCT05267821

RECRUITING Phase 1

Safety and Efficacy of Expanded, Universal Donor Natural Killer Cells for Relapsed/Refractory AML

NCT05503134

RECRUITING Phase 1

Pilot Study of Haploidentical Donor Adenovirus Specific T-lymphocytes to Treat Refractory Adenovirus Infections

NCT04722029

RECRUITING Early Phase 1

A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion

NCT04655404

RECRUITING Phase 2

Two-Year Study of the Safety and Efficacy of the Second-Generation Tissue Engineered Vascular Grafts

NCT04467671

RECRUITING

Early Predictors of Necrotizing Enterocolitis in Neonates

NCT03210831

RECRUITING NA

Radiotracer-Based Perfusion Imaging of Patients With Peripheral Arterial Disease

NCT03622359

RECRUITING

Genetics of Congenital Heart Disease

NCT01192048

ACTIVE NOT RECRUITING

Metabolomic Profiling of Racial Disparity

NCT06266429

ACTIVE NOT RECRUITING NA

Regional Anesthesia EMG Study

NCT06287151

ACTIVE NOT RECRUITING NA

VR-PAT for Pain and Anxiety Management During Pediatric Dermatologic Laser Procedures

NCT05645224

ACTIVE NOT RECRUITING NA

Evaluating an Intervention to Prevent Overdoses in Rural and Urban Counties

NCT05463341

ACTIVE NOT RECRUITING

Natural History Study of Patients With VCP-related Disease

NCT04823143

ACTIVE NOT RECRUITING

Early Prediction of Spontaneous Patent Ductus Arteriosus (PDA) Closure and PDA-Associated Outcomes

NCT03782610

ACTIVE NOT RECRUITING Phase 4

GM-CSF for Reversal of immunopAralysis in pediatriC sEpsis-induced MODS Study

NCT03769844

ACTIVE NOT RECRUITING Phase 1

A Phase 1b Study of PTC596 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma and High Grade Glioma

NCT03605550

ACTIVE NOT RECRUITING Phase 1

Haploidentical Hematopoietic Cell Transplantation for Children With Hematologic Malignancies and Myelodysplasia

NCT03431090

ACTIVE NOT RECRUITING

Characterization of Clinical Skeletal and Cardiac Impairment in Carriers of DMD and BMD

NCT02972580

ACTIVE NOT RECRUITING Phase 2

MIBG Therapy for Patients With MIBG Avid Tumors

NCT02378428

NOT YET RECRUITING Phase 1

Phase I/IIa Trial of scAAV1.tMCK.NTF3 for Treatment of CMT1A

NCT03520751

NOT YET RECRUITING Phase 3

Comparison of Neurocognitive Outcome in Two Standard Regimen for Treatment of Low-risk Medulloblastoma

NCT07291102

NOT YET RECRUITING NA

VR-PAT and fNIRS to Identify CNS Biomarkers of Pain

NCT06303687

NOT YET RECRUITING Phase 1

Phase I/II Clinical Trial of Universal Donor CD33 CAR Natural Killer Cells for AML

NCT07026942

NOT YET RECRUITING Early Phase 1

Safety and Feasibility of CD19 CAR T Cells Using CliniMACS Prodigy for Relapsed/Refractory CD19 Positive ALL and NHL

NCT05779930

COMPLETED

Spanish BMT4me Usability & Acceptability

NCT06361173

COMPLETED

Preoperative Survey to Evaluate Patient Allergy

NCT05670756

TERMINATED NA

A Pilot Study of Collaborative Assessment and Management of Suicidality With Suicidal Children ("CAMS-4Kids")

NCT04119648

COMPLETED Phase 3

Baclofen for Children With Rumination Syndrome

NCT05975684

COMPLETED NA

Psychologically Informed Education Intervention for Adolescents With Atraumatic Lower-Extremity Injuries

NCT05701618

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Phase Distribution

PhaseTrial count
Phase 1 21
Phase 2 29
Phase 3 8
Phase 4 5

What the Pipeline for Nationwide Children's Hospital Shows

According to the ClinicalTrials.gov registry, Nationwide Children's Hospital is linked to 188 US clinical trials across every stage of research activity. Of those, 29 studies are currently recruiting, about 15% of the sponsor's indexed portfolio, and 122 are already marked complete, representing roughly 65% of the total.

The phase mix for Nationwide Children's Hospital reports 13 late-stage studies (Phase 3 and Phase 4 combined) and 50 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Nationwide Children's Hospital is High Grade Glioma with 8 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.