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RECRUITING NA

Applying Directly Observed Therapy to Hydroxyurea to Realize Effectiveness

NCT06264700 · View on ClinicalTrials.gov ↗

Study Summary

This study is for caregivers of young children with sickle cell disease and adolescents with sickle cell disease who are currently prescribed hydroxyurea and are receiving care at one of the study sites. The study will assess retention and engagement during a pilot randomized control trial comparing video directly observed therapy (VDOT) to attention control. We also hope to understand more about patient and family preferences longer-term adherence monitoring and intervention. Participants will use an electronic adherence monitor (provided by the study team) to measure how often they are taking their hydroxyurea. Participants will also be asked to complete questionnaires throughout the study period to provide information about their expectations for, experience with, and satisfaction with the study materials.

Conditions Studied

Interventions

  • BEHAVIORAL Video Directly Observed Therapy (VDOT)
  • BEHAVIORAL Health Reminder Tip Alerts

Study Locations (3)

Illinois

  • Lurie Children's Hospital — Chicago

Ohio

  • Nationwide Children's Hospital — Columbus

Rhode Island

  • Hasbro Children's Hospital — Providence

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2024-07-11
Est. Completion 2025-12
Phase NA

Sponsor

Nationwide Children's Hospital

239 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06264700

The ClinicalTrials.gov registry entry for NCT06264700 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Nationwide Children's Hospital, which has 239 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Sickle Cell Disease appearing as the primary indexed condition, and to 2 interventions — of which Video Directly Observed Therapy (VDOT) is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06264700 reports 3 study locations spanning 3 distinct geographic areas — top geographies include Illinois, Ohio, Rhode Island. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06264700 about?

NCT06264700 is a clinical study titled "Applying Directly Observed Therapy to Hydroxyurea to Realize Effectiveness". This study is for caregivers of young children with sickle cell disease and adolescents with sickle cell disease who are currently prescribed hydroxyurea and are receiving care at one of the study sites. The study will assess retention and engagement during a pilot randomized control trial comparing...

What is the current status of trial NCT06264700?

This trial is currently recruiting. It is a NA study. The enrollment target is 60 participants. The study started on 2024-07-11. Estimated completion is 2025-12.

What conditions does trial NCT06264700 study?

This clinical trial studies the following conditions: Sickle Cell Disease. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06264700?

The interventions under investigation include: Video Directly Observed Therapy (VDOT) (BEHAVIORAL), Health Reminder Tip Alerts (BEHAVIORAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06264700?

This trial is sponsored by Nationwide Children's Hospital, which has 239 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06264700 being conducted?

This trial has 3 study locations across Illinois, Ohio, Rhode Island. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial