National Institutes of Health Clinical Center (CC)

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, National Institutes of Health Clinical Center (CC) sits in the top decile of US sponsors by registered trial count (#107 of 15,742 sponsors by registered trial count).

338 total trials 22 currently recruiting 272 completed early-phase tilt top decile by trial count

National Institutes of Health Clinical Center (CC): 338 sponsored US clinical trials, 22 recruiting.

National Institutes of Health Clinical Center (CC) sponsors 338 registered US clinical trials on ClinicalTrials.gov, 22 of them currently recruiting, and 272 completed. 17 of these trials are in Phase 3-4 (later-stage) and 121 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 8 trials.

Top-decile sponsor footprint

National Institutes of Health Clinical Center (CC) ranks in the top decile of sponsors by registered trial count (#107 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 60/100

272 of 308 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (88.3%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

338 total, page 2 of 7

COMPLETED

Motivations, Expectations, and Decision-making of Sickle Cell Patients in Clinical Research

NCT03709303

COMPLETED NA

A Response Modulation Hypothesis of Socioemotional Processing Associated With Alcohol Use Disorder

NCT03535129

COMPLETED Phase 1

Impact of Weekly Administration of Rifapentine and Isoniazid on Steady State Pharmacokinetics of Tenofovir Alafenamide in Healthy Volunteers (YODA)

NCT03510468

TERMINATED

Near-infrared Spectroscopy and Electroencephalography to Assess Cortical Activation During Motor Tasks in Infants and Toddlers With and Without Cerebral Palsy

NCT03434080

TERMINATED NA

Aerobic Exercise in Women With Systemic Lupus Erythematosus

NCT03186794

COMPLETED NA

Brief Mindfulness Meditation Course to Reduce Stress in Healthcare Professionals

NCT03781336

COMPLETED

Characteristics and Outcomes of a Capacity-to-Consent Assessment Service

NCT03258606

TERMINATED

Dopamine and Motor Learning in Cerebral Palsy

NCT02839733

COMPLETED

The National Institutes of Health Measure of Healing Experience of All Life Stressors

NCT03871270

COMPLETED

Tool to Assess Psycho-Social-Spiritual Healing: Cognitive Interviewing

NCT02664402

TERMINATED NA

Effect of Exercise Training on Physical, Cognitive, and Behavioral Function in People With TBI

NCT02504866

COMPLETED

Influence of Psychosocial Distress and Lifetime Trauma Exposure on Traumatic Stress Among Oncology Patients on Clinical Trials

NCT02948413

COMPLETED NA

A Clinical Trial of a Gamified Attention Bias Modification Training in Anxious Youth

NCT03283930

COMPLETED Phase 2

Immunogenicity of Recombinant Vesicular Stomatitis Vaccine for Ebola-Zaire (rVSV∆G-ZEBOV-GP Vaccine)

NCT02788227

COMPLETED

Longitudinal Changes in the Oral and Gut Microbiome of Individuals With Alcohol Dependence

NCT02911077

COMPLETED

Complement (C1q) Binding to HLA Antibodies in a Solid-phase Immunoassay and Clinical Effect on Platelet Transfusion

NCT02858323

COMPLETED

Zika Virus and Related Arbovirus Infections in Deferred Blood Donors (ZVADD)

NCT02794181

COMPLETED Phase 1

Impact of Once-Weekly Rifapentine and Isoniazid on the Steady State Pharmacokinetics of Dolutegravir and Darunavir Boosted With Cobicistat in Healthy Volunteers

NCT02771249

TERMINATED NA

LC Bead LUMI Radio-Opaque Embolic Beads to Detect and Characterize the Vascularity of Hepatic Tumors

NCT02649868

COMPLETED

Evaluation of MiSeq for Microbial Identification in Specimens

NCT02578875

COMPLETED

Family Caregiving Role Adjustment and Dyadic Mutuality

NCT02566174

COMPLETED NA

Evaluating a New Knee-Ankle-Foot Brace to Improve Gait in Children With Movement Disorders

NCT01961557

COMPLETED Phase 2

Integrated Imaging Strategy to Phenotype Progression of Liver Tumors During and After Chemoembolization

NCT02471313

COMPLETED NA

The NIH Exercise Therapy for Advanced Lung Disease Trials: Response and Adaptation to Aerobic Exercise in Patients With Interstitial Lung Disease

NCT02019641

COMPLETED Phase 2

Neurocognitive Driving Rehabilitation in Virtual Environments (NeuroDRIVE) as an Adjunctive Intervention for Traumatic Brain Injury

NCT02411227

TERMINATED

Tests of Functional Magnetic Resonance Imaging Techniques

NCT01712633

COMPLETED Phase 4

Community-based Treatment of Chronic Hepatitis C Monoinfection and Coinfection With HIV in the District of Columbia

NCT02339038

COMPLETED Phase 2

Effectiveness of a Stress Reduction Intervention in Caregivers of Allogeneic Hematopoietic Stem Cell Transplant (HSCT) Recipients

NCT02257853

COMPLETED

Pharmacokinetics of Granulocyte Colony Stimulating Factor in the Breast Milk of Volunteer Peripheral Blood Stem Cell Donor

NCT02322151

TERMINATED

Imaging Techniques in CT: Technical Development

NCT02242448

COMPLETED

Sleep Disturbance and Relapse in Individuals With Alcohol Dependence: An Exploratory Mixed Methods Study

NCT02181569

TERMINATED Phase 1

Evaluation of Budesonide and How It Interacts With Antifungal Drugs in People With Gastrointestinal Graft-Versus-Host Disease

NCT01950507

COMPLETED Phase 2

Safety, Tolerability, and Efficacy of Asunaprevir and Daclatasvir in Subjects Coinfected With HIV-HCV

NCT02124044

COMPLETED

A Description of Bacteria in the Mouths of Patients With Severe Aplastic Anemia

NCT01900119

TERMINATED Phase 1

Fusion Guided Thermal Ablation Combined With External Beam Radiation for Hepatic Neoplasms

NCT01862718

COMPLETED

Web-based Patient Reported Outcome Measurement Information System (PROMIS ) to Explore Burden and Stress in Cancer Caregivers (BaSiC2)

NCT01981538

COMPLETED NA

Study of New Software Used During Ablations

NCT01906021

COMPLETED

Point Prevalence Study of Multidrug-Resistant Organism Carriage by Healthcare Personnel

NCT01952158

COMPLETED Phase 1

The Interaction of Two HIV Medications With Blood Clot Medications in Healthy Volunteers

NCT01896622

COMPLETED

Muscle Strength Loss and Its Effect on Knee Cap Motion in Volunteers With Anterior Knee Pain

NCT01862731

COMPLETED Phase 2

Comparison of Cortisol Pump With Standard Treatment for Congenital Adrenal Hyperplasia

NCT01859312

COMPLETED Phase 2

Fluoroscopy or 3-D Roadmap Imaging Software for Liver Tumor Treatment

NCT01818440

COMPLETED

Gadofosveset Trisodium for Heart Imaging Studies

NCT01853592

TERMINATED Phase 2

Ponatinib for Advanced Medullary Thyroid Cancer

NCT01838642

TERMINATED

Brain Imaging for HIV-Associated Thinking and Mood Disorders

NCT01692236

TERMINATED

Detecting Respiratory Viruses in Upper and Lower Respiratory Tract Samples

NCT01597089

COMPLETED

Estimating Brain Biomechanics Using MRI

NCT01633268

COMPLETED NA

Yoga as Self-Care for Arthritis in Minority Communities

NCT01617421

COMPLETED Phase 1

A Comparison of Methods for Assisting Needle Angle Selection During Image-guided Tissue Biopsy

NCT01218854

COMPLETED Phase 1

Antiretroviral Drug Interaction Study in Volunteers With HIV

NCT01479361

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Phase Distribution

PhaseTrial count
Phase 1 74
Phase 2 47
Phase 3 6
Phase 4 11

What is open in the National Institutes of Health Clinical Center (CC) pipeline

22 recruiting of 338 indexed (7% open); 272 completed (80%).

Phase mix: 17 late (III/IV) vs 121 early (I/II) (early-phase heavy).

Top condition: Healthy (8 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

National Institutes of Health Clinical Center (CC): open-pipeline peers nationwide

Peers matched on 338 registered trials and 7% open enrollment, not the therapeutic-area sidebar.

National Institutes of Health Clinical Center (CC) sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0100200300400500 0%5%10%15%20%25% Total trials Recruiting share National Institutes of Health Clinical Center (CC)Cedars-Sinai Medical CenterOhio State University Comprehensive Cancer CenterNational Institute on Drug Abuse (NIDA)Children's Oncology GroupAlliance for Clinical Trials in OncologyNICHD Neonatal Research NetworkInsmed IncorporatedBaylor Breast Care Center
National Institutes of Health Clinical Center (CC) sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

National Institutes of Health Clinical Center (CC) sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 338 trials (± recruiting share)

Sponsors near 7% open enrollment (± trial volume)

What to do with this National Institutes of Health Clinical Center (CC) page

338 registered trials is a research-attention snapshot, not an endorsement of National Institutes of Health Clinical Center (CC) or any single study.

  • 22 of National Institutes of Health Clinical Center (CC)'s trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Healthy is the condition National Institutes of Health Clinical Center (CC) studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Healthy trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

National Institutes of Health Clinical Center (CC) pipeline card: 338 registered trials from official public datasets.Report a data error.