Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT01160471 · ClinicalTrials.gov registry record
Noninvasive Imaging of Heart Failure: A Pilot Study
A clinical trial of MRI and Myocardial Fibrosis, sponsored by National Institutes of Health Clinical Center (CC).
- Completed
- Registry status
- 62
- Enrollment target
- 1
- Study location
NCT01160471: Completed study of MRI and Myocardial Fibrosis, sponsored by National Institutes of Health Clinical Center (CC).
NCT01160471 is a study of MRI and Myocardial Fibrosis that has completed, run by National Institutes of Health Clinical Center (CC). The registered enrollment target is 62 participants, below the 2,042-participant average among 5 other MRI trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01160471, a study of MRI and Myocardial Fibrosis, has completed, sponsored by National Institutes of Health Clinical Center (CC).
- COMPLETED
- Registry status
- 62 participants
- Enrollment target
- 1
- Study location
Study Summary
Background: \- Heart failure is a common cardiovascular disorder whose incidence increases with age, affecting up to 10% of people older than 65 years of age. As the population ages, the prevalence and cost of heart failure will continue to rise. Researchers are interested in using noninvasive imaging methods to better understand the symptoms and effects of heart failure. Objectives: \- To conduct a noninvasive comparative imaging study of individuals with heart failure. Eligibility: \- Individuals at least 18 years of age who have been diagnosed with heart failure (with at least mild symptoms and slight limitations on physical activity). Design: * This study will last approximately 2 years and will require four visits to the National Institutes of Health Clinical Center, with one screening visit and three study visits. * Participants will be screened with a full medical history and physical examination, as well as blood and urine samples. * Participants will have the following tests during each study visit: * Physical examination * Blood and urine samples * Cardiac magnetic resonance imaging * Cardiac computerized tomography to study the blood vessels in and leading to the heart * Echocardiogram to evaluate heart function * Electrocardiogram to measure heart electrical activity * The three study visits will take place 1 year apart. Participants will also receive follow-up phone calls 6 months after the first and second visits. * No treatment will be provided as part of this protocol.
Primary Outcome
The primary aim of this protocol is to investigate noninvasive imaging methods for quantifying diffuse myocardial fibrosis with cardiac magnetic resonance imaging(CMR) in heart failure patient
Conditions Studied
Study Locations (1)
Maryland
- National Institutes of Health Clinical Center, 9000 Rockville Pike - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 62 participants |
| Start Date | 2010-07-01 |
| Est. Completion | 2019-10-30 |
What the finished NCT01160471 record still lists
NCT01160471 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 62 participants, a relatively small participant target, below the 2,042-participant average among 5 other MRI trials with a reported enrollment target (97% lower).
The record links to 3 conditions, with MRI appearing as the primary indexed condition, and to 0 interventions.
NCT01160471 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT01160471 about?
NCT01160471 is a clinical study titled "Noninvasive Imaging of Heart Failure: A Pilot Study". Background: \- Heart failure is a common cardiovascular disorder whose incidence increases with age, affecting up to 10% of people older than 65 years of age. As the population ages, the prevalence and cost of heart failure will continue to rise. Researchers are interested in using noninvasive imag...
What is the current status of trial NCT01160471?
This trial is currently completed. The enrollment target is 62 participants. The study started on 2010-07-01. Estimated completion is 2019-10-30.
What conditions does trial NCT01160471 study?
This clinical trial studies the following conditions: MRI, Myocardial Fibrosis, Acquired Heart Disease.
Who is sponsoring clinical trial NCT01160471?
This trial is sponsored by National Institutes of Health Clinical Center (CC), which has 338 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01160471 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for MRI
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
VAPORHCS/OHSU J: MRI and Devices
RECRUITING · NA
-
Effects Ketone Supplement and Alcohol on Brain Metabolism
RECRUITING · Phase 2
-
The Impact of Whey Protein on Frailty in Older Adults Classified as Pre-frail
RECRUITING · NA
-
TRANBERG® Transperineal MR/US Fusion Laser--Induced Thermal Therapy for Men With Prostate Cancer
RECRUITING · NA
-
Serial MRI Scans During Radiation Therapy
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT03231150 · 62 participants · NA
Plantar Fasciitis Randomized Clinical Control Trial
- NCT03458676 · 62 participants · NA
Radiologic Pathologic Correlation of Advanced MR Imaging to Guide the Biopsy of Cerebral Malignancies
- NCT03596086 · 62 participants · Phase 1
HSV-tk + Valacyclovir + SBRT + Chemotherapy for Recurrent GBM
- NCT03603405 · 62 participants · Phase 1
HSV-tk and XRT and Chemotherapy for Newly Diagnosed GBM
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI