National Institutes of Health Clinical Center (CC)

338 total trials 22 currently recruiting 272 completed

National Institutes of Health Clinical Center (CC) sponsors 338 registered US clinical trials on ClinicalTrials.gov, 22 of them currently recruiting, and 272 completed. 17 of these trials are in Phase 3-4 (later-stage) and 121 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 8 trials.

Trial Pipeline

338 total, page 1 of 7

RECRUITING

Toward Ubiquitous Lower Limb Exoskeleton Use in Children and Young Adults

NCT06998134

RECRUITING NA

Characterization of Nociception Phenotype in Individuals With Intellectual Disability

NCT05473429

RECRUITING

Blood Sampling Pre- and Post-Propofol Administration to Characterize the Blood Proteome Using Different Research Assays

NCT07295795

RECRUITING

Metagenomics Next-generation Sequencing Approach to Detect Microbial DNA/RNA Overtime in Individuals Undergoing Hematopoietic Stem Cell Transplant

NCT06904053

RECRUITING Phase 1

Resiniferatoxin for the Management of Refractory Morton s Neuroma Pain

NCT05695339

RECRUITING

A Natural History Study of RYR1-Related Disorders

NCT06287762

RECRUITING

Investigating New Methods to Study Movement in Children and Young Adults With Movement Disorders.

NCT06498596

RECRUITING

The Impact of Heavy Alcohol Use on Saliva and Oral Health

NCT06684483

RECRUITING NA

A Nature-Based Virtual Reality (VR) Intervention in Family Caregivers of Allogeneic Hematopoietic Stem Cell Transplant (HSCT) Recipients

NCT05909202

RECRUITING NA

Evaluating Long-term Use of a Pediatric Robotic Exoskeleton (P.REX/Agilik) to Improve Gait in Children With Movement Disorders

NCT05726591

RECRUITING

Dietary Intake and Dietary Behaviors in Adults With Sickle Cell Disease

NCT05170412

RECRUITING NA

Dietary Behavior Intervention in African Americans at Risk for Cardiovascular Disease

NCT04305431

RECRUITING

Samples From Human Subjects to Facilitate Basic, Translational and Clinical Research

NCT03253705

RECRUITING Phase 2

Spironolactone for Pulmonary Arterial Hypertension

NCT01712620

RECRUITING

Cerebral Palsy and the Study of Brain Activity During Motor Tasks

NCT01829724

RECRUITING

Natural History Study of Biomarkers in Pulmonary Arterial Hypertension

NCT01730092

RECRUITING Phase 4

Improving White Blood Cell Collection From Healthy Donors

NCT01553214

RECRUITING

Imaging Techniques in MRI

NCT01130545

RECRUITING

Study of Lung Proteins in Patients With Pneumonia

NCT00077909

RECRUITING

MRI Study of Musculoskeletal Function

NCT00051857

RECRUITING

Collection and Distribution of Blood Components From Healthy Donors for In Vitro Research Use

NCT00001846

RECRUITING

Human Movement Database

NCT00001252

ACTIVE NOT RECRUITING

Cefiderocol vs Best Available Therapy for Carbapenem-resistant Acinetobacter Baumannii-calcoaceticus Complex Infections: A Target Trial Emulation

NCT07226557

ACTIVE NOT RECRUITING

Pre- vs Post-Pandemic Risk-adjusted Survival Rates in the US Hospitals

NCT06651645

ACTIVE NOT RECRUITING Phase 1

COVID-19, Chronic Adaptation and Response to Exercise (COVID-CARE)

NCT04595773

ACTIVE NOT RECRUITING

Evaluation of Atherosclerotic Plaques in Abdominal CT Studies

NCT04652973

ACTIVE NOT RECRUITING

Development and Evaluation of Techniques for Computer Aided Detection and Diagnosis From Existing Radiologic Images

NCT04579237

ACTIVE NOT RECRUITING

Assisted Suicide in Switzerland

NCT04261088

ACTIVE NOT RECRUITING Phase 2

Treatment of Hemochromatosis

NCT00007150

NOT YET RECRUITING

Pulmonary Hypertension (PH) Biorepository for Translational Research

NCT07647549

COMPLETED NA

Feasibility of Measuring Volume of Inspiration Via Noninvasive Motion Sensors

NCT06609616

COMPLETED

Adolescents Seeking COVID Vaccination (Teen COVID Vax)

NCT05537103

COMPLETED NA

Mediterranean-like Unprocessed (CLEAN-MED) Diet Intervention Study of the Gut Microbiome of Healthy Adults

NCT05411120

TERMINATED NA

Electromagnetic Tracking and Optical Imaging With ICG for Hepatic Biopsies

NCT04258566

COMPLETED NA

The Effect of a Combined Nature-based and Virtual Mindfulness Intervention on Perceived Stress in Healthcare Workers

NCT04846790

COMPLETED

Hospital COVID-19 Surge and Associated Mortality Risk

NCT04688372

COMPLETED

Trimethoprim-Sulfamethoxazole vs Levofloxacin as Targeted Therapy for Stenotrophomonas Maltophilia Infections: a Retrospective Cohort Study

NCT04639817

COMPLETED

Saliva as Source of Detection for SARS-CoV-2

NCT04424446

COMPLETED

Cardiopulmonary Inflammation and Multi-System Imaging During the Clinical Course of COVID-19 Infection in Asymptomatic and Symptomatic Persons

NCT04401449

COMPLETED

Plasma Collection From Convalescent and/or Immunized Donors for the Treatment of COVID-19

NCT04360278

COMPLETED

Collecting Interval Timed Incisional Epidermal and Dermal Tissue Samples During Surgical Procedures to Profile Temporal Response of Tissue After Noxious Stimuli

NCT04224870

COMPLETED NA

Translational Development of Photon-counting CT Imaging

NCT03878134

COMPLETED Early Phase 1

A Dose-Finding Study of AG-348 in Sickle Cell Disease

NCT04000165

TERMINATED Phase 2

The SOLID Platelet Study

NCT03712618

COMPLETED Phase 1

Impact of Steady State Cobicistat and Darunavir/Cobicistat on the Pharmacokinetics and Pharmacodynamics of Oral Anticoagulants (Rivaroxaban, Apixaban) in Health Volunteers

NCT03864406

TERMINATED

Characterizing Fatigue Experienced by Registered Nurses

NCT03789188

COMPLETED NA

RCT of Web-Based Behavioral Sleep Intervention for Individuals With Alcohol Use Disorder

NCT03493958

COMPLETED Phase 1

The Influence of ANS-6637 on Midazolam Pharmacokinetics in Healthy Volunteers

NCT03831971

COMPLETED

Focus Groups to Determine Surrogates Views Regarding Patient Preference Predictors

NCT02898194

COMPLETED Phase 1

PET Imaging of the Dopaminergic and Serotonergic Systems in Treated HIV Positive Subjects

NCT03581305

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Phase Distribution

PhaseTrial count
Phase 1 74
Phase 2 47
Phase 3 6
Phase 4 11

What the Pipeline for National Institutes of Health Clinical Center (CC) Shows

According to the ClinicalTrials.gov registry, National Institutes of Health Clinical Center (CC) is linked to 338 US clinical trials across every stage of research activity. Of those, 22 studies are currently recruiting, about 7% of the sponsor's indexed portfolio, and 272 are already marked complete, representing roughly 80% of the total.

The phase mix for National Institutes of Health Clinical Center (CC) reports 17 late-stage studies (Phase 3 and Phase 4 combined) and 121 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for National Institutes of Health Clinical Center (CC) is Healthy with 8 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.