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NCT07295795 · ClinicalTrials.gov registry record
Blood Sampling Pre- and Post-Propofol Administration to Characterize the Blood Proteome Using Different Research Assays
A clinical trial of Critically Ill Surgical Patients, sponsored by National Institutes of Health Clinical Center (CC).
- Recruiting
- Registry status
- 10
- Enrollment target
- 1
- Study location
NCT07295795: Recruiting study of Critically Ill Surgical Patients, sponsored by National Institutes of Health Clinical Center (CC).
NCT07295795 is a study of Critically Ill Surgical Patients that is actively recruiting participants, run by National Institutes of Health Clinical Center (CC). The registered enrollment target is 10 participants. The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07295795, a study of Critically Ill Surgical Patients, is actively recruiting participants, sponsored by National Institutes of Health Clinical Center (CC).
- RECRUITING
- Registry status
- 10 participants
- Enrollment target
- 1
- Study location
Study Summary
Background: Propofol is a drug that helps people fall asleep quickly and stay asleep during surgery, so they do not feel any pain. This drug is also used to sedate critically ill people who must be on a ventilator (a machine to help them breathe). To better understand how to interpret blood tests in these ill people, researchers need to know more about how the drug itself may change proteins in the blood. Objective: To collect blood samples from people before and after propofol is administered for surgery. Eligibility: People aged 18 years or older who are scheduled for surgery that requires sedation with propofol. Design: Participants will have data collected. This data will include age, sex, and ethnicity. They will be asked about their medical history. Participants will have blood samples collected before and after they receive propofol for their surgery. The blood will be collected from lines already installed for the surgery; no new needlesticks will be done for the study. A total of 3 teaspoons of blood will be drawn. The samples will be compared to each other to look for any changes caused by the drug. No follow-up visits are required.
Primary Outcome
The investigators would like to use the O-link Explore HT and SomaScan Discovery v4.1assay on samples from participants who are critically ill. In order to do this understanding, the impact of propofol on each analyte must be understood as there is potential for interference with propofol in each sample.
Conditions Studied
Study Locations (1)
Maryland
- National Institutes of Health Clinical Center - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2026-02-10 |
| Est. Completion | 2026-12-31 |
What NCT07295795 shows while recruiting
NCT07295795 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 10 participants, a relatively small participant target.
The record links to 1 condition, with Critically Ill Surgical Patients appearing as the primary indexed condition, and to 0 interventions.
NCT07295795 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT07295795 about?
NCT07295795 is a clinical study titled "Blood Sampling Pre- and Post-Propofol Administration to Characterize the Blood Proteome Using Different Research Assays". Background: Propofol is a drug that helps people fall asleep quickly and stay asleep during surgery, so they do not feel any pain. This drug is also used to sedate critically ill people who must be on a ventilator (a machine to help them breathe). To better understand how to interpret blood tests i...
What is the current status of trial NCT07295795?
This trial is currently recruiting. The enrollment target is 10 participants. The study started on 2026-02-10. Estimated completion is 2026-12-31.
What conditions does trial NCT07295795 study?
This clinical trial studies the following conditions: Critically Ill Surgical Patients.
Who is sponsoring clinical trial NCT07295795?
This trial is sponsored by National Institutes of Health Clinical Center (CC), which has 338 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07295795 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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