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NCT00357058 · ClinicalTrials.gov registry record
Role of Brain Region Changes in Tactile (Touch) Ability Following Nerve Block
A clinical trial, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- Completed
- Registry status
- 90
- Enrollment target
NCT00357058: Completed study, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
NCT00357058 is a clinical trial that has completed, run by National Institute of Neurological Disorders and Stroke (NINDS). The registered enrollment target is 90 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00357058 has completed, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- COMPLETED
- Registry status
- 90 participants
- Enrollment target
Study Summary
This study will examine the role of different brain regions in tactile (touch) ability after application of a tourniquet (inflated blood pressure cuff). When the forearm is deprived of blood for a short period of time, tactile ability in the other hand improves. This study will try to learn what causes this improvement. Healthy normal volunteers are eligible for this study. Candidates will have a brief medical history and physical examination. Volunteers will undergo two experiments, described below, that involve the following procedures: * Ischemic nerve block - A blood pressure cuff is inflated for 35-40 minutes around the elbow area (also around the calf for Experiment 2 - see below). The resulting numbness, tingling, loss of muscle strength, and discoloration of the forearm and hand disappear within minutes after the cuff is deflated. * Magnetic resonance imaging (MRI) - This test uses a magnetic field and radio waves instead of X-rays to produce images of brain structure and function. The volunteer lies on a stretcher that is moved into the scanner (a cylinder containing a strong magnet), wearing earplugs to protect the ears from loud thumping noises that occur with electrical switching of radio frequency circuits. The subject can communicate with an investigator by intercom at all times during the scan. * Transcranial magnetic stimulation (TMS) - An insulated wire coil is placed on the patient's scalp. A brief electrical current passes through the coil, creating a magnetic pulse that travels through the scalp and skull and causes small electrical currents in the outer part of the brain. The stimulation may cause muscle hand or arm twitching or transient tingling in the forearm, head or face muscles. * Tactile spatial acuity testing - The subject's left arm is placed in a cast and the left index finger is immobilized for this test which involves identifying the direction of grooves applied to the finger. Experiment 1 This experiment measures changes in tac
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 90 participants |
| Start Date | 2001-12-12 |
| Est. Completion | 2007-12-28 |
What the finished NCT00357058 record still lists
NCT00357058 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 90 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT00357058 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00357058 about?
NCT00357058 is a clinical study titled "Role of Brain Region Changes in Tactile (Touch) Ability Following Nerve Block". This study will examine the role of different brain regions in tactile (touch) ability after application of a tourniquet (inflated blood pressure cuff). When the forearm is deprived of blood for a short period of time, tactile ability in the other hand improves. This study will try to learn what cau...
What is the current status of trial NCT00357058?
This trial is currently completed. The enrollment target is 90 participants. The study started on 2001-12-12. Estimated completion is 2007-12-28.
Who is sponsoring clinical trial NCT00357058?
This trial is sponsored by National Institute of Neurological Disorders and Stroke (NINDS), which has 567 total clinical trials registered on ClinicalTrials.gov.
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