National Institute of Neurological Disorders and Stroke (NINDS)

567 total trials 48 currently recruiting 467 completed

National Institute of Neurological Disorders and Stroke (NINDS) sponsors 567 registered US clinical trials on ClinicalTrials.gov, 48 of them currently recruiting, and 467 completed. 16 of these trials are in Phase 3-4 (later-stage) and 158 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 23 trials.

Trial Pipeline

567 total, page 8 of 12

COMPLETED

Magnetic Resonance Imaging of the Brain in Social and Emotional Reasoning

NCT00060853

COMPLETED

Hypnosis in Autonomic Function

NCT00061009

COMPLETED

Magnetic Resonance Imaging of the Brain in Emotional Processing

NCT00061204

TERMINATED

Evaluation of Primary Chronic Autonomic Failure

NCT00059033

COMPLETED

Brain Plasticity of Verbal Memory in the Blind

NCT00059189

COMPLETED Phase 2

Effect of Talampanel (an AMPA Receptor Blocker) on Brain Activity

NCT00057460

COMPLETED

The Role of Gene Changes in Brain Tumor Formation and Growth

NCT00059020

COMPLETED

Postural Control in the Elderly

NCT00059501

COMPLETED

Single Photon Emission Computed Tomography to Study Receptors in Parkinson's Disease

NCT00058721

COMPLETED

Development of Techniques for Use in MRI With a Magnetic Field of 7 Tesla

NCT00056914

COMPLETED

Neurophysiological Studies in Patients With Paroxysmal Hyperkinetic Movement Disorders

NCT00056888

COMPLETED

Brain Dynamics Involved in Generating Tics and Controlling Voluntary Movement

NCT00056420

COMPLETED Phase 1

Nervous System Function in Normal Volunteers During Cycling Training

NCT00055588

COMPLETED Phase 1

Dextromethorphan to Treat Patients With Voice Spasms

NCT00055549

COMPLETED Phase 2

Transcranial Direct Current Stimulation to Treat Symptoms of Parkinson's Disease

NCT00082342

COMPLETED

Ischemic Nerve Block to Improve Hand Function in Stroke Patients

NCT00056706

COMPLETED

Registry of Fabry Disease - A Multicenter Observational Study

NCT00055016

COMPLETED

Brain Use of Sensory Information to Generate Movement

NCT00055289

COMPLETED

Survey of Sensory and Motor Tricks in Focal Dystonia

NCT00054652

COMPLETED

Effects of Antiepileptic Drugs on Brain Excitability

NCT00054990

COMPLETED

Effect of Ropinirole on Spinal Cord Reflexes and Restless Legs Syndrome

NCT00051961

COMPLETED

Single Photon Emission Computed Tomography (SPECT) to Study Paroxysmal Hyperkinetic Movement Disorders

NCT00051337

COMPLETED

Brain Encoding for Memory

NCT00051870

COMPLETED Phase 3

Minocycline to Treat Amyotrophic Lateral Sclerosis

NCT00047723

COMPLETED

Learning a Motor Task Through Observation

NCT00050869

COMPLETED Phase 2

Rituximab to Treat Neuropathy With Anti-MAG Antibodies

NCT00050245

COMPLETED Phase 1

Preliminary Study of Transcranial Magnetic Stimulation for Stroke Rehabilitation

NCT00050128

COMPLETED

Transcranial Magnetic Stimulation and Electrical Stimulation of Nerves to Study Focal Dystonia

NCT00050024

COMPLETED Phase 2

Alpha-Galactosidase A Replacement Therapy for Fabry Disease

NCT00048906

COMPLETED Phase 1

Effects of Direct Current Brain Stimulation on Cognition

NCT00048698

COMPLETED

Brain Inhibition of Muscle Movement in Normal Volunteers

NCT00047957

COMPLETED Phase 2

Transcranial Magnetic Stimulation to Treat Epilepsy

NCT00048490

COMPLETED

Comparison of the Risk of Stroke With On- Versus Off-Pump Coronary Artery Bypass Grafting

NCT00046410

COMPLETED Phase 2

ReoPro and Retavase to Treat Acute Stroke

NCT00046293

COMPLETED

Transcranial Magnetic Stimulation to Study Imagination of Movement

NCT00046215

COMPLETED

Role of Hormones in Susceptibility to Seizures in Women With Epilepsy

NCT00044252

COMPLETED Phase 2

OGT 918-006: A Phase I/II Randomized, Controlled Study of OGT 918 in Patients With Neuronopathic Gaucher Disease

NCT00041535

COMPLETED

How the Loss of Dopamine and Dopamine-Restoring Medicines Affect Movement Performance

NCT00040196

COMPLETED

MRI Language Studies in Young Children

NCT00039845

COMPLETED

Genetic Studies to Identify Stroke Subtypes and Outcome

NCT00357513

COMPLETED Phase 2

JP-1730 to Treat Parkinson's Disease

NCT00040209

COMPLETED

Nerve Stimulation to Modify a Spinal Reflex

NCT00039819

COMPLETED Phase 2

Immunological Mechanisms of Hematopoietic Stem Cell Transplantation in Multiple Sclerosis

NCT00342134

COMPLETED NA

Hypothermia to Treat Severe Brain Injury

NCT00040339

COMPLETED

Functional Coupling of Cortico-Cortical and Cortico-Muscular Connections During Motor Movements: An Electrocorticographic Study of Ipsilateral Motor Control

NCT00036595

COMPLETED

Study of GABA-A Receptors in the Generation of Tics in Patients With Tourette's Syndrome

NCT00034398

COMPLETED

Magnetic Resonance Imaging in Children and Adults Using Arterial Spin Tagging Techniques

NCT00034073

COMPLETED

Study of Tics in Patients With Tourette's Syndrome and Chronic Motor Tic Disorder

NCT00033995

COMPLETED Phase 2

High-Dose Intravenous Immunoglobulin to Treat Cerebellar Degeneration

NCT00034242

COMPLETED

MRI Brain Studies in Patients With HTLV-1 Associated Myelopathy/Tropical Spastic Paraparesis

NCT00034723

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Phase Distribution

PhaseTrial count
Phase 1 80
Phase 2 78
Phase 3 11
Phase 4 5

What the Pipeline for National Institute of Neurological Disorders and Stroke (NINDS) Shows

According to the ClinicalTrials.gov registry, National Institute of Neurological Disorders and Stroke (NINDS) is linked to 567 US clinical trials across every stage of research activity. Of those, 48 studies are currently recruiting, about 8% of the sponsor's indexed portfolio, and 467 are already marked complete, representing roughly 82% of the total.

The phase mix for National Institute of Neurological Disorders and Stroke (NINDS) reports 16 late-stage studies (Phase 3 and Phase 4 combined) and 158 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for National Institute of Neurological Disorders and Stroke (NINDS) is Healthy with 23 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.