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NCT00028379 · ClinicalTrials.gov registry record · NA
Enhancement of Use-Dependent Plasticity by Somatosensory Stimulation in Chronic Stroke
A NA study, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- Completed
- Registry status
- NA
- Development phase
- 52
- Enrollment target
NCT00028379 is a NA study that has completed, run by National Institute of Neurological Disorders and Stroke (NINDS). The registered enrollment target is 52 participants.
The verdict
NCT00028379, a NA study, has completed, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- COMPLETED
- Registry status
- NA
- Development phase
- 52 participants
- Enrollment target
Study Summary
Recent studies have demonstrated that electrical stimulation delivered over the skin increases the muscle strength as measured by a dynamometer in chronic stroke patients. We recently also found out that such stimulation enhances the ability of healthy brains to learn faster, enhancing the beneficial effects of the motor training. The purpose of this study is to find out if this stimulation can enhance the ability of stroke patients to experience plastic changes in the brain. It may aid in the development of new strategies for rehabilitation after brain injury in the future. A clinical and neurological exam will be administered. Each patient will participate in three different sessions separated by at least 48 hours: a 2-hour peripheral nerve stimulation to the weak hand, a 2-hour peripheral nerve stimulation to the leg, and no stimulation. The sessions will be randomly ordered. A magnetic resonance imaging scan of the brain will be done as well. Nerve stimulation will be done by transcranial magnetic stimulation (TMS). In TMS, the head is immobilized within a frame. An insulated coil wire is placed on the scalp and brief electrical current passed through it. Participants may be asked to perform movements, do simple tasks, or simply tense muscles. Electrical activity of the muscles will be recorded with a computer. Some experiments may be recorded on videotape. Participants must be stroke patients who have recovered to the point of being able to make thumb movements, and the stroke must have occurred more than 6 months ago.
Interventions
- PROCEDURE Transcranial magnetic stimulation (TMS)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 52 participants |
| Start Date | 2001-12 |
| Est. Completion | 2005-11 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00028379
The ClinicalTrials.gov registry entry for NCT00028379 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 52 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Institute of Neurological Disorders and Stroke (NINDS), which has 567 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Transcranial magnetic stimulation (TMS) is the first listed.
NCT00028379 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00028379 about?
NCT00028379 is a clinical study titled "Enhancement of Use-Dependent Plasticity by Somatosensory Stimulation in Chronic Stroke". Recent studies have demonstrated that electrical stimulation delivered over the skin increases the muscle strength as measured by a dynamometer in chronic stroke patients. We recently also found out that such stimulation enhances the ability of healthy brains to learn faster, enhancing the beneficia...
What is the current status of trial NCT00028379?
This trial is currently completed. It is a NA study. The enrollment target is 52 participants. The study started on 2001-12. Estimated completion is 2005-11.
What interventions are being tested in trial NCT00028379?
The interventions under investigation include: Transcranial magnetic stimulation (TMS) (PROCEDURE).
Who is sponsoring clinical trial NCT00028379?
This trial is sponsored by National Institute of Neurological Disorders and Stroke (NINDS), which has 567 total clinical trials registered on ClinicalTrials.gov.
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