National Institute of Environmental Health Sciences (NIEHS)

145 total trials 15 currently recruiting 124 completed

National Institute of Environmental Health Sciences (NIEHS) sponsors 145 registered US clinical trials on ClinicalTrials.gov, 15 of them currently recruiting, and 124 completed. 3 of these trials are in Phase 3-4 (later-stage) and 7 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Asthma, with 8 trials.

Trial Pipeline

145 total, page 2 of 3

COMPLETED

Parkinson's Genes and Environment Study

NCT00367900

COMPLETED

Influence of Social and Environmental Factors on Women's Reproductive Function in a Maya Community of Guatemala

NCT00340782

COMPLETED

Genetic Measurements in Blood Cells of Children Taking Adderall or Methylphenidate

NCT00341029

COMPLETED

Studies of the Natural History and Pathogenesis of Autoimmune/Connective Tissue Diseases

NCT00341679

COMPLETED

Pathogenesis and Genetics of Environmental Asthma Ozone Study

NCT00574158

COMPLETED

Prospective Lung Transplant Database for Genetic Research

NCT00339209

COMPLETED

Mechanisms of Lung Allograft Rejection

NCT00340418

COMPLETED

Can Immune Parameters Predict Acute and Chronic Rejection in Lung Recipients?

NCT00340951

COMPLETED Phase 2

Dust Mite Allergen Reduction Study

NCT00339690

COMPLETED

Children's Exposures/Health Effects/Diesel Exhaust

NCT00527345

COMPLETED

Hormonal Changes in Early Pregnancy

NCT00340028

COMPLETED Phase 1

Cockroach Allergen Reduction by Extermination Alone in Low-Income, Urban Homes: A Randomized Control Trial

NCT00341445

COMPLETED

Effects of Anti-HIV Therapy on Red Blood Cells of HIV-infected Mothers and Their Infants

NCT00342082

COMPLETED

Diet and Genetic Damage

NCT00340743

COMPLETED

Disease Progression and Activity in Patients With Systemic Lupus Erythematosus

NCT00339261

COMPLETED

Effects of Infant Diets on Estrogen Activity and Development

NCT00340652

COMPLETED

The Sister Study: Genetic and Environmental Risk Factors for Breast Cancer

NCT00047970

COMPLETED

Exposure to Neurotoxins as Risk Factors for ALS

NCT00340301

COMPLETED

Study of Infant Diets on Estrogen Activity and Development

NCT00340665

COMPLETED

Nitric Oxide, LPS and the Pathogenesis of Asthma Phase 1

NCT00671229

COMPLETED

Study of Families With Twins or Siblings Discordant for Rheumatic Disorders

NCT00055055

COMPLETED

Organochlorine Exposure in Relation to Timing of Natural Menopause

NCT00353171

COMPLETED NA

HOME Study (Health Outcomes and Measures of the Environment Study)

NCT00129324

COMPLETED

MR Assessment of Brain Function Altered by Lead Exposure

NCT00283647

COMPLETED

Prevention of Tumor Spread Due to Lung Cancer Surgery

NCT00341380

COMPLETED

Exposure to Neurotoxins as Risk Factors for Amyotrophic Lateral Sclerosis

NCT00339976

COMPLETED

Effect of Environmental Exposures on the Egg Fertilizing Ability of Human Sperm

NCT00012480

TERMINATED NA

Reducing Farmworkers Exposure to Agricultural Chemicals

NCT00298649

COMPLETED

Confirmation of Systemic Autoimmune Diseases in the Agricultural Health Study

NCT00341198

COMPLETED

Healthy Environments Partnership

NCT00042263

COMPLETED

Work and Health Disparities Among Rural Women

NCT00042419

COMPLETED

Postpartum Uterine Regression

NCT00341848

COMPLETED

Early Exposure to Lead and Adult Antisocial Outcomes

NCT00285610

COMPLETED

Early Life Factors and Respiratory Health in Mexico City Children

NCT00342758

COMPLETED

NIEHS/UNC Environmental Polymorphism Study

NCT00340886

COMPLETED

Identifying Residential Hazards Using Home Test Kits

NCT00285532

COMPLETED

Childhood Autism Risks From Genetics and the Environment (The CHARGE Study)

NCT00106652

COMPLETED

Outdoor Allergen Exposure, Sensitivity, and Acute Asthma

NCT00043992

COMPLETED

Gene-Environment Interaction in Prostate Cancer

NCT00041847

COMPLETED

Fibroid Growth Study

NCT00340288

COMPLETED NA

The Genetics of Environmental Asthma

NCT00018096

COMPLETED

Oxidative Stress and Hemodialysis Access Failure

NCT00410449

COMPLETED

Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic

NCT00340769

COMPLETED

Lupus Nephritis: Role of Environmental and Occupational Exposures

NCT00342329

COMPLETED

Socio-economic Status and Age-related Disability in a Biracial Community

NCT00042133

COMPLETED

Farming and Movement Evaluation Study (FAME)

NCT00042120

COMPLETED

Pesticide Exposure Pathways for Farmworker Children

NCT00013754

COMPLETED

Environmental Factors in the Development of Polycystic Ovary Syndrome

NCT00341731

COMPLETED

A Pilot Study to Evaluate the Efficacy of Refined Methods to Mitigate Indoor Allergens in North Carolina and Boston, Massachusetts Homes

NCT00344344

COMPLETED

Parkinson's Diseases Susceptibility Genes and Pesticides

NCT00044590

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Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 5
Phase 3 3

What the Pipeline for National Institute of Environmental Health Sciences (NIEHS) Shows

According to the ClinicalTrials.gov registry, National Institute of Environmental Health Sciences (NIEHS) is linked to 145 US clinical trials across every stage of research activity. Of those, 15 studies are currently recruiting, about 10% of the sponsor's indexed portfolio, and 124 are already marked complete, representing roughly 86% of the total.

The phase mix for National Institute of Environmental Health Sciences (NIEHS) reports 3 late-stage studies (Phase 3 and Phase 4 combined) and 7 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for National Institute of Environmental Health Sciences (NIEHS) is Asthma with 8 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.