National Institute of Environmental Health Sciences (NIEHS)

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, National Institute of Environmental Health Sciences (NIEHS) sits in the top decile of US sponsors by registered trial count (#194 of 15,742 sponsors by registered trial count).

145 total trials 15 currently recruiting 124 completed early-phase tilt top decile by trial count

National Institute of Environmental Health Sciences (NIEHS): 145 sponsored US clinical trials, 15 recruiting.

National Institute of Environmental Health Sciences (NIEHS) sponsors 145 registered US clinical trials on ClinicalTrials.gov, 15 of them currently recruiting, and 124 completed. 3 of these trials are in Phase 3-4 (later-stage) and 7 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Asthma, with 8 trials.

Top-decile sponsor footprint

National Institute of Environmental Health Sciences (NIEHS) ranks in the top decile of sponsors by registered trial count (#194 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

B 88/100

124 of 125 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (99.2%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

145 total, page 2 of 3

COMPLETED

Parkinson's Genes and Environment Study

NCT00367900

COMPLETED

Influence of Social and Environmental Factors on Women's Reproductive Function in a Maya Community of Guatemala

NCT00340782

COMPLETED

Genetic Measurements in Blood Cells of Children Taking Adderall or Methylphenidate

NCT00341029

COMPLETED

Studies of the Natural History and Pathogenesis of Autoimmune/Connective Tissue Diseases

NCT00341679

COMPLETED

Pathogenesis and Genetics of Environmental Asthma Ozone Study

NCT00574158

COMPLETED

Prospective Lung Transplant Database for Genetic Research

NCT00339209

COMPLETED

Mechanisms of Lung Allograft Rejection

NCT00340418

COMPLETED

Can Immune Parameters Predict Acute and Chronic Rejection in Lung Recipients?

NCT00340951

COMPLETED Phase 2

Dust Mite Allergen Reduction Study

NCT00339690

COMPLETED

Children's Exposures/Health Effects/Diesel Exhaust

NCT00527345

COMPLETED

Hormonal Changes in Early Pregnancy

NCT00340028

COMPLETED Phase 1

Cockroach Allergen Reduction by Extermination Alone in Low-Income, Urban Homes: A Randomized Control Trial

NCT00341445

COMPLETED

Effects of Anti-HIV Therapy on Red Blood Cells of HIV-infected Mothers and Their Infants

NCT00342082

COMPLETED

Diet and Genetic Damage

NCT00340743

COMPLETED

Disease Progression and Activity in Patients With Systemic Lupus Erythematosus

NCT00339261

COMPLETED

Effects of Infant Diets on Estrogen Activity and Development

NCT00340652

COMPLETED

The Sister Study: Genetic and Environmental Risk Factors for Breast Cancer

NCT00047970

COMPLETED

Exposure to Neurotoxins as Risk Factors for ALS

NCT00340301

COMPLETED

Study of Infant Diets on Estrogen Activity and Development

NCT00340665

COMPLETED

Nitric Oxide, LPS and the Pathogenesis of Asthma Phase 1

NCT00671229

COMPLETED

Study of Families With Twins or Siblings Discordant for Rheumatic Disorders

NCT00055055

COMPLETED

Organochlorine Exposure in Relation to Timing of Natural Menopause

NCT00353171

COMPLETED NA

HOME Study (Health Outcomes and Measures of the Environment Study)

NCT00129324

COMPLETED

MR Assessment of Brain Function Altered by Lead Exposure

NCT00283647

COMPLETED

Prevention of Tumor Spread Due to Lung Cancer Surgery

NCT00341380

COMPLETED

Exposure to Neurotoxins as Risk Factors for Amyotrophic Lateral Sclerosis

NCT00339976

COMPLETED

Effect of Environmental Exposures on the Egg Fertilizing Ability of Human Sperm

NCT00012480

TERMINATED NA

Reducing Farmworkers Exposure to Agricultural Chemicals

NCT00298649

COMPLETED

Confirmation of Systemic Autoimmune Diseases in the Agricultural Health Study

NCT00341198

COMPLETED

Healthy Environments Partnership

NCT00042263

COMPLETED

Work and Health Disparities Among Rural Women

NCT00042419

COMPLETED

Postpartum Uterine Regression

NCT00341848

COMPLETED

Early Exposure to Lead and Adult Antisocial Outcomes

NCT00285610

COMPLETED

Early Life Factors and Respiratory Health in Mexico City Children

NCT00342758

COMPLETED

NIEHS/UNC Environmental Polymorphism Study

NCT00340886

COMPLETED

Identifying Residential Hazards Using Home Test Kits

NCT00285532

COMPLETED

Childhood Autism Risks From Genetics and the Environment (The CHARGE Study)

NCT00106652

COMPLETED

Outdoor Allergen Exposure, Sensitivity, and Acute Asthma

NCT00043992

COMPLETED

Gene-Environment Interaction in Prostate Cancer

NCT00041847

COMPLETED

Fibroid Growth Study

NCT00340288

COMPLETED NA

The Genetics of Environmental Asthma

NCT00018096

COMPLETED

Oxidative Stress and Hemodialysis Access Failure

NCT00410449

COMPLETED

Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic

NCT00340769

COMPLETED

Lupus Nephritis: Role of Environmental and Occupational Exposures

NCT00342329

COMPLETED

Socio-economic Status and Age-related Disability in a Biracial Community

NCT00042133

COMPLETED

Farming and Movement Evaluation Study (FAME)

NCT00042120

COMPLETED

Pesticide Exposure Pathways for Farmworker Children

NCT00013754

COMPLETED

Environmental Factors in the Development of Polycystic Ovary Syndrome

NCT00341731

COMPLETED

A Pilot Study to Evaluate the Efficacy of Refined Methods to Mitigate Indoor Allergens in North Carolina and Boston, Massachusetts Homes

NCT00344344

COMPLETED

Parkinson's Diseases Susceptibility Genes and Pesticides

NCT00044590

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Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 5
Phase 3 3

What is open in the National Institute of Environmental Health Sciences (NIEHS) pipeline

15 recruiting of 145 indexed (10% open); 124 completed (86%).

Phase mix: 3 late (III/IV) vs 7 early (I/II) (early-phase heavy).

Top condition: Asthma (8 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

National Institute of Environmental Health Sciences (NIEHS): open-pipeline peers nationwide

Peers matched on 145 registered trials and 10% open enrollment, not the therapeutic-area sidebar.

National Institute of Environmental Health Sciences (NIEHS) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0100200300 0%5%10%15% Total trials Recruiting share National Institute of Environmental Health Sciences (NIEHS)Forest LaboratoriesHealthPartners InstituteMylan PharmaceuticalsSCRI Development InnovationsCalifornia Pacific Medical Center Research InstituteUniversity of Rhode IslandSWOG Cancer Research NetworkUniversity of Mississippi Medical Center
National Institute of Environmental Health Sciences (NIEHS) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

National Institute of Environmental Health Sciences (NIEHS) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 145 trials (± recruiting share)

Sponsors near 10% open enrollment (± trial volume)

What to do with this National Institute of Environmental Health Sciences (NIEHS) page

145 registered trials is a research-attention snapshot, not an endorsement of National Institute of Environmental Health Sciences (NIEHS) or any single study.

  • 15 of National Institute of Environmental Health Sciences (NIEHS)'s trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Asthma is the condition National Institute of Environmental Health Sciences (NIEHS) studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Asthma trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

National Institute of Environmental Health Sciences (NIEHS) pipeline card: 145 registered trials from official public datasets.Report a data error.